driver
- 30 Mar 2006 17:03
potatohead
- 11 May 2007 09:49
- 1049 of 1180
no i have not
potatohead
- 11 May 2007 12:46
- 1051 of 1180
according to CT news on ZYC300 write up out soon. taken long enough
WINGNUTS21
- 11 May 2007 18:02
- 1052 of 1180
PH so far u have managed to get 90% of what u say wrong ,so i guess this is more zzzzzzzzz.
smiler o
- 13 May 2007 18:25
- 1054 of 1180
driver, i tend to agree , i have just put mine in the bottom draw and one day !!!! : )
potatohead
- 17 May 2007 13:09
- 1055 of 1180
thefordprefect - 17 May'07 - 13:07 - 17943 of 17944
http://www.osip.com/OSI_027
OSI-027 is a next generation mammalian target of rapamycin (mTOR) kinase inhibitor that inhibits the kinase activity associated with both the TORC1 and TORC2 complexes of mTOR. This dual TORC1 and TORC2 activity differentiates our compound from rapamycin and the various related analogs, or rapalogs, that are currently in clinical development in that these molecules only inhibit TORC1 activity. In addition, researchers at OSI have found that the combination of an EGFR inhibitor, like Tarceva, with an inhibitor of mTOR is synergistic in certain tumor cell lines. The Company expects to file an IND for OSI-027 before the end of the fourth quarter of 2007.
http://www.wipo.int/pctdb/en/wo.jsp?wo=2003027671
Inventors: HAYES, Ian [GB/IE]; EiRx Therapeutics Ltd, Cork Airport Business Park, Kinsale Road, Cork (IE).
KROEMER, Guido [FR/FR]; Le Centre National de la Recherche Scientifique, 3 rue Michel-Agne, F-75794 Paris Cedex 16 (FR).
FERRI, Karine [FR/FR]; Le Centre National de la Recherche Scientifique, 3 rue Michel-Agne, F-75794 Paris Cedex 16 (FR).
CASTEDO, Maria [FR/FR]; Le Centre National de la Recherche Scientifique, 3 Rue Michel-Agne, F-75794 Paris Ceded 16 (FR).
Agent: MASCHIO, Antonio; D Young & Co, 21 New Fetter Lane, London EC4A 1DA (GB).
Priority Data: 0123025.9 25.09.2001 GB
Title: APOPTOSIS
Abstract: The present invention relates to the modulation of apoptosis, in particular it relates to the use of mTOR in the modulation of syncitial apoptosis. A method for the identification of further molecules involved in apoptosis, and the use mTOR in the treatment of disease are also disclosed. In addition, assays associated with the identification of such molecules are disclosed.
Cheers, Mike
smiler o
- 17 May 2007 20:36
- 1056 of 1180
Yawn !!!
potatohead
- 18 May 2007 11:20
- 1057 of 1180
is yesterdays share magazine
EiRx Therapeutics (ERX:AIM) Interims PTP: -0.9m (-0.9m) Divi: n/a (n/a)
Trials of the companys breast cancer product ERX3722 showed a 50% reduction in
tumour size, which it says endorses its decision to change its business model from
a research services company to a drug discoverer.
It discovered ERX3722 using its EnPad candidate screening technology and
believes this is capable of developing more products targeting different genes and
tumour types.
A share placing in September raised 500,000 but it is now looking for opportunities
such as grant funding, partnering deals with larger businesses and M&A
options to help it progress. Shares have been on a downward spiral for the last six
months but they should recover if it is successful in securing a deal.
■ Shares says: Needs a deal to help advance its technology.
Marcel1970
- 18 May 2007 11:23
- 1058 of 1180
Sounds Good
potatohead
- 18 May 2007 11:54
- 1059 of 1180
well we know they were in talks for a JV a good while back.. but dont know whats holding it all up
potatohead
- 18 May 2007 14:37
- 1061 of 1180
well we have already been aware they have been in negotiations for some time.. just wish we knew whats holding it all up
potatohead
- 21 May 2007 10:04
- 1062 of 1180
OSI webcast tomorrow should have news on the osi-027, as I understand this is the one that belongs to us
smiler o
- 23 May 2007 16:26
- 1064 of 1180
it does !! still need something soon me finks !!
driver
- 25 May 2007 15:18
- 1065 of 1180
Disappointing to say the least but life goes on at ERX.
These four kinases rejoin the panel of apoptosis targets currently subject to collaborative discussions with other parties.'
Contract Update
http://moneyam.uk-wire.com/cgi-bin/articles/200705251455062749X.html