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EIRx Therapeutics PLC (ERX)     

driver - 30 Mar 2006 17:03

About ERIX
EiRx Therapeutics is a specialist provider of pre-clinical therapeutics to the pharmaceutical industry. Our unique scientific expertise and knowledge in the field of Apoptosis provide a sound base to discover and develop new medicines that will safely and selectively repair this natural process in disease. The potential benefits from these new medicines are enormous, since as many as 70% of all human disease have some defect in the control of Apoptosis.
Apoptosis - the biological process that determines whether cells in our bodies live or die...
http://www.eirx.com/index.html

Purchased some of these on the strength of the PROGRESS UPDATE looks promising.
http://moneyam.uk-wire.com/cgi-bin/articles/200603200701130254A.html

ERX interview with John Pool
http://www.wallstreetreporter.com/interview.php?id=18589&player=real
Latest News
CANCER COLLABORATION WITH BIOMERIEUX SA
http://moneyam.uk-wire.com/cgi-bin/articles/200607120700230534G.html
Biomerieux Web Site
http://www.biomerieux.com/servlet/srt/bio/portail/home
ABOUT ERX Focus Of The Month
http://www.billamag.net/focus-document-text.asp?FocusTextID=1
ERX pdf filehttp://www.eirx.com/eirx_heading_images/Yokohama2005.pdf
19/09/2006 A 50% reduction in breast tumour volume size seen with Eirx lead molecule in animal studies
http://moneyam.uk-wire.com/cgi-bin/articles/200609190700171175J.html

Past and present collaborative partners include:


* bioMieux SA
* Almac Diagnostics Ltd
* Merck & Co, Ltd
* Biofocus plc
* MGI Pharmaceuticals, Inc
* OSI Pharmaceuticals, Inc
* Sareum plc
* Regen Therapeutics plc
* SR Pharma plc

driver - 25 May 2007 16:58 - 1068 of 1180

Plenty left.

Past and present collaborative partners include:

* bioMieux SA
* Almac Diagnostics Ltd
* Merck & Co, Ltd
* Biofocus plc
* MGI Pharmaceuticals, Inc
* OSI Pharmaceuticals, Inc
* Sareum plc
* Regen Therapeutics plc
* SR Pharma plc

driver - 26 May 2007 15:36 - 1069 of 1180

Left alone :-(

smiler o - 26 May 2007 17:19 - 1070 of 1180

No still here driver ;)

driver - 27 May 2007 11:58 - 1071 of 1180

smiler
Well it can't get any worse there must be some good news some where in ERX

David10B - 27 May 2007 14:03 - 1072 of 1180

Some good posts here chaps I am taking a look at the company, loving the South of Ireland is a big plus too.

All input welcomed unlike some here I like both postive and negative views please.

Have agreat day.

driver - 01 Jun 2007 14:26 - 1073 of 1180

Second day of rises the sp is coming back strong to a more sensible level, after its fall.

moneyplus - 01 Jun 2007 14:37 - 1074 of 1180

might have known--as soon as I move on!!!

driver - 01 Jun 2007 14:39 - 1075 of 1180

mp
Drivers tips theres post for you.

potatohead - 05 Jun 2007 09:34 - 1076 of 1180

Mercier et Camier - 4 Jun'07 - 18:28 - 20257 of 20271

Taken from another investor site. Thanks to NR1 Trader.

http://investing.reuters.co.uk/news/articleinvesting.aspx?type=smallCapsNews&storyID=2007-06-04T143445Z_01_L04782436_RTRIDST_0_UKSMALLCAPOFTHEWEEK-EIRX.XML

UK small cap of the week - EiRx Therapeutic

LONDON, June 4 (Reuters) - Shares in Ireland's EiRx Therapeutic Plc spiked more than 50 percent last week, making it the top performer among FTSE Small Cap and FTSE AIM All Share companies.

The cancer drug development minnow -- which had previously seen its shares more than halve this year following a steady decline -- suddenly attracted the attention of risk-friendly retail investors, a trader said.

"They (EiRx) had got so low and attracted people who like to gamble .. the shares move around and people love that," he said, adding that the stock held similarities with health firm Ultrasis Plc -- another group which has seen its shares go backwards this year.

Retail share discussion boards have been a hot-bed of discussion among EiRx investors in recent days, with speculation abounding that the firm could be set to receive a grant from the Irish government or even get taken over.

EiRx firm could not immediately be reached for comment.

When posting first-half results at the end of March, EiRx said its aim was to take its cancer therapies to the late preclinical stage of development when other companies typically attract major licensing deals.

"Your board is considering multiple routes ... including grant funding, partnering with larger businesses and in-licensing and M&A options," EiRx said in the statement.

Shares in the company had fallen back slightly by 1430 GMT on Monday, down 5.7 percent at 0.165 penny, valuing it at 4.9 million pounds ($9.7 million). ((Reporting by John Bowker, Editing by Dan Lalor

Reuters Messaging: john.bowker.reuters.com@reuters.net

e-mail: john.bowker@reuters.com;

telephone: +44 20 7542-8454)) ($1 = 0.5033 pound)

Keywords: UKSMALLCAPOFTHEWEEK EIRX/

potatohead - 05 Jun 2007 11:18 - 1078 of 1180

I believe the results for zyc300 are out this week driver, so keep a close eye out for the rns.. Probably will be Thursday or Friday

potatohead - 05 Jun 2007 17:23 - 1079 of 1180

Driver.. Reuters posted this this afternoon


EiRx close to announcing Irish govt grant - source
Tue Jun 5, 2007 3:13 PM BST
Email This Article | Print This Article | RSS [-] Text [+]
LONDON, June 5 (Reuters) - Irish drug development company EiRx Therapeutic Plc (ERX.L: Quote, Profile , Research) is close to announcing that it has received a cash grant from the Irish government, a source familiar with the situation said on Tuesday.

The cancer-focused firm has been the subject of retail investor speculation that it could be close to receiving the funds, and featured as Reuters' UK small cap of the week on Monday after a recent 50 percent share price spike.

It is not yet clear how much the grant will be for, or exactly when it will be announced, the source added.

http://investing.reuters.co.uk/news/articleinvesting.aspx?type=allBreakingNews&storyID=2007-06-05T141338Z_01_L05856281_RTRIDST_0_EIRX-GRANT.XML

EiRx could not be reached for comment.



Shares in the loss-making company were up 3 percent at 0.17 pence by 1355 GMT, valuing it at 5 million pounds ($10 million).

kkeith2000 - 05 Jun 2007 18:03 - 1080 of 1180

It would be nice a little good news considering the recent falls

Thanks ph for keeping us informed

driver - 05 Jun 2007 20:23 - 1081 of 1180

PH
Cheers a nice 50m from the Irish government wouldn't go a miss.

potatohead - 06 Jun 2007 10:21 - 1082 of 1180

oh guess what, we have a new patent

http://v3.espacenet.com/textdoc?DB=EPODOC&IDX=DE60119524T&F=0

driver - 06 Jun 2007 10:41 - 1083 of 1180

Nice to see.

Inventor: COTTER TOM (IE); HAYES IAN (IE); MURPHY FINBARR (IE); SEERY LIAM (IE)
Applicant: EIRX THERAPEUTICS LTD (IE)

potatohead - 29 Jun 2007 13:44 - 1084 of 1180

Genentech bets on small molecules as biogeneric competition looms

28/06/2007 - Genentech has in-licensed two early-stage cancer small molecules developed by Abbott as biogeneric competition is poised to kick off.

Genentech seems to be diversifying its pipeline beyond biologics just at a time where pricing pressure increases and the US government is deciding on clearing a path for the entry of generic versions of biologic drugs on the market.

The biotech giant will work together with Abbott on all aspects of further development and commercialisation of the two drugs, while Abbott will keep their marketing rights outside the US.

Financial terms of the collaboration were not disclosed although some analysts have already estimated the deal as modest.

Genentech said the compounds - ABT-263 and ABT-869 - are targeted therapies that represent promising, unique scientific approaches to treating cancer.

ABT-263, a Bcl-2 family protein antagonist, restores apoptosis - a natural process by which damaged or unwanted cells die and are cleared from the body - in a variety of cancer cells, while ABT-869, a VEGFR-based multi-targeted kinase inhibitor, suppresses tumour growth by preventing the growth of new blood vessels that supply the tumour with oxygen.

Another interesting side of the deal is its early-stage nature - both drugs are in Phase I - which reflects a trend that has been budding over the past year in the biotech industry. After years of biopharma companies showing interest only for late-stage products, it seems that they are shifting their focus to early-stage deals.

According to an Ernst & Young biotech report published recently, this was to some extent because several years of late-stage deal making have left relatively few attractive products in the advanced pipeline that have not already been partnered.

"The trend also reflects that big pharma and big biotechs are eager to energise their pipelines," said the report.

Genentech, the second largest biotech firm in the world with $9.3bn (6.9bn) in sales last year, could have found the right recipe to boost even more its cancer portfolio.


"We believe that these molecules are strong complements to our existing anti- angiogenesis and apoptosis research and development programmes and have the potential to broaden our pipeline with important, innovative compounds," said Hal Barron, senior vice president of Development and chief medical officer for Genentech.

The company who normally specialises in biologics has nevertheless managed to create success with another anti-cancer small molecule: Tarceva (erlotinib hydrochloride).

The biotech firm in-licensed the drug from OSI Pharmaceuticals and brought the drug to the market in 2005.

But Genentech is not the only biotech giant who has been dipping its toe in the small molecule water. Another example of big biotech playing in the big pharma arena is Amgen who recently acquired two small molecule developers in the same week - Alantos for $300m and Ilypsa for $420m.

Meanwhile, the US government is in the process of put in place an approval pathway for generic versions of biologic drugs - a step already taken in Europe where two "biosimilars" are currently marketed.

http://www.biopharma-reporter.com/news/ng.asp?n=77776-genentech-abbott-cancer-biologics


HMMM SOUNDS FAMILIAR

WONDER IF THESE ARE THE MOLECULES OSI RETURNED TO US AND WE HAVE NOW STRUCK A DEAL WITH GENETECH

plm2349 - 12 Jul 2007 15:02 - 1085 of 1180

possible contract soon?????????????????????????????????????????

driver - 12 Jul 2007 15:32 - 1086 of 1180

plm2349
Who knows??????????

David10B - 12 Jul 2007 16:07 - 1087 of 1180

I bought a lump of these back in May after reading here up a bit not much, but still more than happy to hold and top up on any weakness.
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