Biotechs in the US (and those in other countries exposed to the US) will start to move seriously in the Spring.
PRO are due to make a progress announcement on G5 before the end of this year - if this is good, factor in the spring effect and postive sales from other revenue streams we could be looking at 40p-50p this time next year. A two year wait for 1.00 (assuming all goes swimmingly) is about right.