DYOR! (Comments?)

Dam dam dam, missed it, should of bought last night, thought it woul push down one last time, still I think will move to new highs 3 target or q1.

Mmmmhhhh - wondered whether to post as most investors hate to hear about negatives. So just a couple of thoughts in summary and dyor.

1. Check out the fundamentals - valuation vs sales vs future potential royalty income stream.

2. Primarily a diagnostics test development Company - check out the biggest diagnostic players/their turnovers/profits etc. To give you a start - look at Roche/Abbot and Axis Shield platforms/products and how they are sold. Whose platforms will PRM's tests go on to and what is average take? Plus latest in-vitro, simple urine/blood tests cost less than 3c per strip to produce. Work out the quantity of tests/likely royalty income stream should the strips replace some of the more complex assay test platforms used in labs. Did you know there are already simple blood test strips for detecting cancer? Further tests are then done to determine the specific type/location.

3. Why are PRM's diagnostic markers better than existing/others also being developed? At the end of the day the cost of the test/accuracy will determine sales/income levels. Also approval FDA/EU for in-vitro diagnostic systems are simple/fast compared to treatments/drug testing so lead time/patent benefits very limited. Generic/copying with marginally different assays/procedures a problem in diagnostic testing.

4. PRM has been hyped tremendously and often last pump before the decline (end of the push) is takeover rumours which have now surfaced.

In summary this Company is valued at some 250m - work out the number of tests that need to be sold and future royalty income stream to back up this valuation.

Having said all the above I should point out I bought in at under 40p and sold far too early so wtfdik and this could still go to 250 or higher. No position currently.

Good luck everyone.

Suggest today's rise is as a result of Shares making it one of their tips for 2004 (p22).

Rise was because of bse news in the States. Look at PTI first though, it's on the market testing dead carcasses!! PRM do a live test eventually, trouble with that though is the fact the animal can be infected an hour later?!

Hi, my 1st contribution here.

Made good profit on PRM !!! but sold far too soon ! about 140.

I like this format... its like ADVFN which I know.

ADVFN seems dead this weekend so I've joined here...

I'll be trying things...

Buy Proteome Sciences at 200p Argues Andrew Griffiths of The AIM &OFEX Newsletter [links to https://secure.redskyresearch.com/images/aim_ukanalyst_trial.html]

Proteome Sciences is a biotech fledgling that is becoming something of a darling among City life sciences analysts with the shares trebling last year. A hefty research tome from Evolution Beeson Gregory just before Christmas added to the intellectual firepower supporting the price.
To the uninitiated, Proteome might appear to be just another biotech hopeful with no profits and an inflated market capitalisation. Those with long memories will remember the company as Electrophoretics, one of the earliest AIM entrants, and one that always seemed to be promising a breakthrough tomorrow. But nearly a decade after its public company debut and with the same management in place, a positive consensus finally appears to be emerging among analysts about its potential.

Many believe this "technology rich" life sciences company can translate its commercial potential into big revenues, starting from next year, and the market looks like believing the story. Proteome is a significant player in the field of proteomics - the "next revolution in drug discovery" according to some - the analysis of proteins within a cell. The discipline identifies relevant genes and proteins as potential targets for drugs and for diagnostic tools, so producing a new way of identifying and targeting disease.

The technology has allowed the company to identify "biomarkers" within cells, which can be used to diagnose diseases. Proteome has licensing agreements for a stroke biomarker, which can identify whether a patient has suffered a stroke, and a TSE (transmissible spongiform encephalopathies) marker, which may be used to diagnose BSE ("mad cow disease") within cattle and CJD in humans. Each could generate significant royalty payments and the company has another ten markers in the offing. Evolution estimates that the world proteomics market is worth $1.5bn (800m) and is expected to grow at around 20% each year for the next five years.

As far as revenues go, the broker is forecasting sales of 700,000 for the current year, rising sharply to 2.9m in 2004. But it does not expect the company to break even until 2005. Fortunately, Proteome Sciences has the cash (more than 6m) to see it through until then.
Beyond 2005, Evolution expects annual revenues to snowball into tens of millions of pounds. The forecasts rather optimistically assume that each commercialised marker will be used to create a diagnostic product and a pharmaceutical, and that the company will license an average of 1.5 markers per year.
Whether all this is enough to justify a 228m market capitalisation is a moot point but Proteome appears to be making its best progress for a decade. Brokers believe the shares have further to go, which makes them an interesting speculation. Buy. Key Data


EPIC: PRM
Market: AIM
NMS: 10,000
Spread: 199p-201p
Market Cap: 228 million

Andrew Griffiths is managing editor of The AIM &OFEX Newsletter, which specialises in digging out fast growing shares from London's junior stockmarkets. Recent successful tips include Datacash up 252%, Fayrewood up 142%, and Epic Group, up 125%. For a two issue free trial click here [links to https://secure.redskyresearch.com/images/aim_ukanalyst_trial.html].

More good news
GRANT OF US CANCER PATENT FOR NEUROBLASTOMA AND GLIOMA IN BLOOD


http://www.uk-wire.com/cgi-bin/articles/200401260841586140U.html

Why has no one posted any messages for over a month? Have you all sold up and moved on?? New to the site and have found the messages interesting reading. Can not make my mind up whether to sell proteome now or hold on. I read one article recently that told readers to get out of proteome fast but other forecasters seem positive. Its gone down to 206p today. Be intersted to know what anyone elses thoughts are.

after the all the recent falls to low of 139p today ...level 2 is now showing upward movement by the mm's ... recent rns by co no reason for price fall .. now around 143p

Bouncing back nicely - hopefully back to the 2 level.

Barrowboy! Sorry Boroboys

How much of this stock are you now holding


Just been looking at the graph..????

Things are not looking good, I can not help but feel pessamistic when it comes to Proteome Sciences after investing a substantial figure in the company, nothing in real terms but a hell of a lot for a 19 yr old student I am fearing the worst. Whats everyone else thinking?

gild18er
Have you got a stop-loss in place?
I fear that on no news these will fall even further. I am watching from the side-lines to buy in but don't want to catch a falling knife. On balance I believe in their 'story' but further drastic falls may force their hand to make an announcement more substantive than their last one. And when will that be? Tomorrow, or days, weeks, months? Thats the uncertainty of it all.
If you are over 30% down then IMHO I'd hold and ride it out. If less perhaps sell and try and get back in at a lower price. Or a mixture of both. But then this is just my view. I'm sure others would disagree. In the end its your call. Good luck.

Gild18er, you should sell and cut your loss. Don't hold out for a bounce in the price, it may fall a lot further before it comes.

What about getting in now? Big drop and now at 122 to buy? Have not held before but just sold BGY to lock in profit - I know they're still going up but I'm chicken. Or anything better today to go for???????

amberjane
Tricky to call the floor on these at the moment, but I think if you look at the medium to long term ( but don't discount the short term)you would be getting in at a good price, and if you have faith in their story, which I do then you can ride out the current volitility. I wouldn't be suprised if they dropped more after a little rally over the next couple of days or so but wouldn't count on it. If there is very heavy buying tomorrow it could suggest the floor has been reached. My conclusion is to stay out at the moment, why take such a risk?
For another to go for try BPRG. A large contract plus broker's note is imminent and the price is relatively low at the moment. In fact if you get in tomorrow (wednesday) before it you will be lucky. We have been told by management within two weeks but rumours are flying that the brokers note is due Thursday, so the contract should (but anything can happen)be announced before or with it. I am very heavily into these. No ramp intended. DYOR.

No e-mail to contact u direct but thanks, what price is good for BPRG today, don't have level 2, abowt 113?

OT
amberjane
113 is good at this stage IMHO. 110 has proved a good support in the recent past so its not too far off. Some on another BB think maybe early next week if not this week for Brokers note and contract so don't panic if its not out by Friday. All rumours etc to be treated with a healthy pinch of salt! Its close though. Are you aware of the another BB starting ADV..? Good threads there on BPRG and research website given in the header of the main one. If you can't access the BB the research web page is: http://mysite.freeserve.com/bprg/index.html
Good luck

Many thanks, will consider. Ta

Well did my research and decided, went to buy and after my first quote at 114 upped the amount & it went to 116 :-{{{{

Oh sorry, excellent for all you holders. Luv me x