Shares mag. recommending this stock this week. Is this going to be our killer this christmas!!!! any comments anyone?????

The market gets what its been waiting for,and its down 30%,i give up.

Annoyingly (maybe not now), my trailing stop banked the profit for me Thursday and I was looking to buy them back and add at the same time. Too busy Friday however glad I waited as it looks like the market does not like the comments and downgrades and the possibility of delays to market. I still believe that CEN will deliver M6G, lets face it, it is as good as morphine and without the side affects. I have researched over the weekend and the report has been put out on many pharmaceutical and clinical websites. Staying put for now whilst this bottoms out, I've learnt before that you cannot beat the market with your own loyalty but I will be back in once the dust settles.

andysmith,i will hold and add @6p,think thats the best option for me,feel sorry for those that bought recently @9 on the day of the RNS,i agree long term it should be a winner.

It would appear though that whilst Goldman are selling that others are adding to their holdings. Two recent RNS, Gartmore now exceeded 10% and Unniverstites Superannuation exceeded 3%. Maybe this is why the drop, Goldman may still have >10m shares and the buyers want a cheaper price just in case there are delays? Watching closely here but I have time after this fall. CEN will deliver M6G if as good as reported, the side affects of morphine are not good. I think CENES need to come out and respond to the comments of Karl Keegan and advise whether another phase III for Europe is required before licensing deals are likely.

Announcement today: Gartmore declare a 10.3% (49,977,758 shares) holding in CEN.

True Ludlow,but its had NO impact on the SP!!,
Market knows more than i do.

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Hope you are right!!,but for now its not good.

capetown, the 32% reduction in dry retching/vomiting for European PIII M6G in comparison to morphine was still an encouraging result. Have you sold?

Ludlow,i agree with all that you are saying,I have NOT sold out,just simply stating that the sp is grimm,i will add @6 p to my other holding and wait.

CeNeS Investor Chronicle 23rd February. I read with interest the report page 14 on CeNeS.. However I disagree with Karl Keegan, analyst at Canaccord Adams who has downgraded from buy to hold.. As he says the nausea reduction was not statistically significant and that CeNeS could have to do another trial..

Trials delivered Stong results with CeNeS saying that M6G showed significant reduction in post operative nausea and vomiting compared to morphine.. That on its own is a major benefit to patients.. Its bad enough being in pain.. Reduction of nausea and vomiting is a key factor.. Thank you CeNeS for all the trials that your company has undertaken to prove that M6G is the better drug.. For pain relief with reduced side effects..

With the Gartmore investment CeNeS will soon bounce back...

So why has the share price bombed again this morning

CEN Level 2:

5 market makers blue.

capetown
I agree not worried I will also add if it dips any lower.

Much better day today,anothe few mill buys and we might get a tick up.

Having spoken to the CEN, my understanding is they have other statistically significant data that supports a reduction in nausea but they did not choose those particular data measurements as one of the two primary endpoints. Obviously the statistically significant 32% reduction in retching/vomiting, which was the other primary endpoint, still stands.

barclays now have 14% holding!!!!

Nice to see some good news on a s**t day!

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Objective Capital have issued a new report on CEN saying the failure to meet the primary endpoint for PIII M6G in the nausea indication, will necessitate a further Phase 3 trial (probably as part of a US Phase 3 trial) and delay launch until 2010.