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Phytopharm (PYM)     

Gill Bates - 23 Nov 2004 16:30

Any ideas anyone?

Tonker - 25 Apr 2006 13:06 - 26 of 94

these shares are booming, I am not a glory hunter but think i was right about there move north, I am going to stock up

Tonker - 25 Apr 2006 13:41 - 27 of 94

up 13% today

Tonker - 25 Apr 2006 21:21 - 28 of 94

Also large x trade went through today, 2,459,817 shares in this one deal... past experiance tells me that whenever a large x trade goes through on a penny share it is a good signal... we will have to wait and see but i feel this one should be in your watchlist... there is a separate thread about large x trades, but can not remember its title, sorry..... comments?

Mega Bucks - 25 Apr 2006 21:29 - 29 of 94

http://www.moneyam.com/TradersRoom/posts.php?tid=9156#lastread

Here you go...

Mega...

Tonker - 26 Apr 2006 09:58 - 30 of 94

These guys are booming, feel they could boom up to 145p... big profit availible.... am I talking to myself... Tonker

jimward9 - 26 Apr 2006 10:17 - 31 of 94

Phytopharm PLC has appointed Teather & Greenwood Ltd as joint financial adviser and stockbroker.

Hope you are right TONKER I need 102p to break even, now they have a broker they have a chance.

Tonker - 26 Apr 2006 12:56 - 32 of 94

Feel things are changing for this company, sp is really moving and i feel that there is a lot more to come.... As I said earlier think the results that will be out on the 8 may will be good... lets hope they ramp up! It is a shame other people are not as interested in these type of shares, feel that oil/mining shares dominate these threads... I can only hope people have been reading these posts and have taken action, for i feel that it will be a little late now to make a super profit (but not too late to make a modest 50%)!!!
Regards Tonker
NB. I am a share holder in this company... my opinion will be biased, but I am fundermentally honest...

Tonker - 27 Apr 2006 08:40 - 33 of 94

still going up...

hangon - 05 May 2006 16:00 - 34 of 94

Tonker, I hold also - from about 1 average; here's some hope-bias!
.......The problem with PYM was timing - they were caught up in the Dot-com fiasco and had a huge value - this was always a long-term bet and as far as I see it, they are delivering slowly. The Doggy deal is a regular income and the food-suppliment (if all goes well) should be massive for a small-cap company.
The Results are unlikely to give us anything unexpected, I hoping..... although some further deals would be nice.
PYM always did look super-value but there is no g'tee - whereas Oil-stocks are heading North because Oil is a commodity and that's is unlikely to drop - even $50/b looks cheap "now".
The other problem for PYM was the animal activists - "--so what it's tested on animals? It's a dog medicine, what would you like it tested on, Eh? .."
This also caused the sp to fall, since there was no regular income and folk worried there might be pipeline disruption. The loss of their broker didn't help, but they were not essential to the business, or listing, I understand.
PYM is fully ISA-able and at current prices (say sub-50p) look to turn a decent profit, for the patient.

Tonker - 05 May 2006 21:20 - 35 of 94

Thanks hangon, thanks for your comment, am hoping for a quick short term profit with these ones, have already made 45% on these ones and am looking to get out soon.. could resist waiting to hear the results this monday... maybe some more good news as well... as I have mentioned earlier that large x trades in penny shares normally means a good signal for the SP.... now some might say that the new broker will be the good news but there could be more

hangon - 06 May 2006 15:27 - 36 of 94

Quite a bit of Good News has washed-away the market's recent opinions about PYM.
I can understand you wanting to bank a profit (no harm, etc.), but if the pipeline of Royalties is real, then you are throwing away a yield that could be a considerable benefit. Something to consider - for example LLOY is about 7% yield, right now, but anyone taking a punt when the sp was just over 5 will be reaping a yield near 10% (on their investment) - there aren't mny legit places for that return and if there is a TO (for LLOY) a decent cash benefit too.
/
I've been reading stories that BigPharma is starting to worry about their futures - with Patents running out and little to replace them. In the past the "generic" market was a bit jokey and Doctors kept prescribing the old "brands" (since they wern't paying for it). However, now things are different and generics are seen as "good" - that's why I'm holding Bioprogress - that have started to market their "alternative delivery" not just to Big Pharms (=Patent extension), but also directly into the secondary market by offering ingenious packaging/delivery - like PYM they aren't there yet.....but if they succeed then they could become Big Pharma as (BP's) fortunes wane - there is no g'tee that the likes of Glaxo will continue to dominate, say in the next 20 years.
- Buying out PYM and BPRG would seem to me to be a very cheap option for senior Staff at Glaxo, that wish to retire comfortably.
(above is not intended to be a rant, or ramp - I'm not buying these, just holding)

We(holders) are in a position where but for a real accident, these companies are about to move into the early-stages of being BIG ( needs abt. 5-years of growth ). By then they will have regular incomes and the mind-set to continue formulating new products - then by about 20years hence, they may lose their edge, like Big Pharma - and some new development will attempt to topple them.

What's certain IMHO, is my holding in SKP (skypharma) will remain in the jam-tomorrow position they've held for so long. Micap[MIC] may be paired with them, soon, also. However both are in "alternative delivery" and such techniques could (the watch-word) mean that failed drugs suddenly become attractive, FWIW I would support a refinancing of SKP/MIC if they would buy-up recently failed patents, where the fault was in the delivery. New-delivery might (a big guess!) be a way to make fortunes in health esp as the World pop. ages........
Wow!
I must lie down, now.

hangon - 02 Jun 2006 15:06 - 37 of 94

PYM is on the up, with the doggy-cream launched and sp rising albeit slowly from 40p to wisker near 60p - that's a 50% rise which is GOOD in anyone's money.

Some way to get to 1 and another 50% increase will get harder, as the sp reaches "fair value" - which many hope is just a tad over 1.

It would be nice to know there are other products in the pipeline - that's my worry; - but I'm happy with my 40% profit, allowing for my timing error and spread.

Confidant - 19 Jul 2006 10:47 - 38 of 94

Broker T&G initiating coverage with buy and price target of........120p . Should get the share back to above 50p even in these markets

Confidant - 25 Jul 2006 11:02 - 39 of 94

Here comes the move , some sniffy buying after report digested ??

Confidant - 07 Aug 2006 13:42 - 40 of 94

55p bid --- nice 23% return --- moving to LRL for similar

RD - 26 Dec 2006 10:10 - 41 of 94

From Boxing Day's Independent:

Cactus that promises to curb the appetite


By Cahal Milmo


Published:26 December 2006








A multi-million pound race between the world's biggest food companies is under way to tackle the global obesity epidemic by producing the first clinically-tested "satiety pill".


Three conglomerates - the Anglo-Dutch firm Unilever, France's Danone and Kraft in America - are researching compounds to achieve the hallowed goal of inducing people to eat less by suppressing their appetite.


With 300 million people worldwide rated as overweight or obese, the annual global cost of treatment and economic loss from the epidemic is now 100bn.


Scientists are increasingly placing their hopes in a range of natural substances which have the effect of duping the brain into "satiety" - the feeling of a full stomach. In the last 12 months, patents have been given appetite-suppressing extracts including Korean pine nuts and chicory roots. But at the head of the race to cash in on the 3bn worldwide market for dietary control products is Hoodia gordonii - a spiny cactus, which takes five years to mature in the Kalahari desert.


Hoodia contains a secret weapon - a compound known as P57 which has been isolated by a British bio-technology company, Phytopharm, and is now at the heart of a 21m research scheme funded by Unilever.


Phytopharm announced last month that it was making good progress in clinical trials of P57. The cucumber-like core of the Hoodia has been used for centuries by indigenous San tribesmen to stave off hunger pangs. They eat it on long hunting trips.


Unilever has struck a deal with the San to pay the tribe a royalty from the sales of any product containing P57 to be used in a social programme.


Phytopharm, which will also receive a royalty on sales of all products containing its Hoodia extract, warned last month that it was talking with authorities to curtail the sale of "Hoodia" products on the internet which claim to cause weight loss. Unilever is working to launch a range of "hunger buster" products based on Hoodia in 2009.


Phytopharm found that the compound closely mimics a natural substance in the body which sends a satiety message to the hypothalamus - the part of the brain that controls appetite.


Trials have shown that those taking P57 can cut their consumption by as much as 1,000 calories per day. The recommended calorie total for an adult man is 2,500 per day and for a woman, 2,000. A Unilever spokesman said: "We don't want to put our name to something that is not backed 100 per cent by the science behind it. We are now satisfied that the product works and has the potential to help with weight management."


The cash and energy being pumped into Unilever's project is mirrored by its rivals. Danone has patented new types of dietary fibre which slow the passage of food through the digestive system, making people feel full for longer. Kraft is working on a special form of starch which resists being broken down by the body, again designed to create the sense that the stomach is full.


But a senior executive with one conglomerate told The Independent: "Satiety has the potential to be one of the biggest earners of the next five years."


Many of the substances, including P57, work by affecting a mechanism in the ileum, part of the lower intestine, where the presence of fat triggers a response of satiety to the brain.


This "ileal brake" is triggered or mimicked by the compounds by disguising the fat molecules until they reach the ileum. In one case, the body is convinced it has consumed 500 calories when in reality it has had just 190.


However, according to Gary Frost, professor of nutrition and dietetics at Surrey University, humans have a "squirreling" instinct which encourages them to eat to excess in preparation for times of food scarcity. "There is a sense that for the company or companies that can isolate a proven appetite suppressant, there is a market waiting that would entail the vast majority of the population," he said. "It is a glittering prize but a controversial one - can you confidently say that one food will halt your desire for another?"


Neville Rigby, spokesman for the International Obesity Task Force, said: "The key to tackling obesity is eating decent food and balancing your calorie intake with the amount of energy you burn. There is no magic bullet."

hangon - 25 Apr 2007 11:11 - 42 of 94

Moving up over last few days, is this because more good news is likely? I suspect not, since the co just ann. their canine product is going World-wide (soon), but it might be anticipation of income towards the end of 2007.

The previous wrier is dismissing the appetite suppressant by sugesting humans will resist any attempt...etc.
It is a "magic bullet" IF you can find that part of us that says we are full - but I suspect we may see a situation where our appetite is "remapped" so that the hunger is overcome at lower levels of satisfaction. The problem fat people have is that they have stretched their stomachs - so more food is needed to reach the point of satisfaction....by allowing the satisfaction to come sooner (the amount based on their intake of this replacement food) they will be able to let the stomach reduce in size so they can find goodness in "healthier" foods. Presently they crave fats because these produce the "satisfaction" that we humans crave. It is this "remapping" that I'm hoping is at the foundation of the hoodia commercial product.
(That product has to have a balance of nutrients so anyone that switches to it will remain "balanced" at least until they can eat normally.)
Of course the key to obesity is ...to eat less (to match your exercise, etc), -but this is the goal...not the route. Without help, the route would be extremely painful as few of us can reduce our intake ( say by one third), .....even though it would "probably" be good for us.
The key, IMHO for normal people is alway to keep a little bit of hunger present, that way you know you haven't overdone it. However, what served past generations (the storing of fats for winter) is not needed, since we have food in the shops all-year.
I hold PYM and hope their products are successful, but the market over-hyped the SP until 2005, since when its been under 1 (and often under 50p) which is right IMHO for a co. with no turnover.
I suspect the "biggie" is a few years away, but now might be the time to tuck away.

andysmith - 25 Apr 2007 21:55 - 43 of 94

For whatever reason this has moved up 20% in two days on relatively low volume.
Nearly bought at 40p (bugger!!) but will keep an eye on this, maybe another milestone payment is due or announcement about a product launch?

hangon - 16 Nov 2007 15:00 - 44 of 94

No need to worry - you can pick them up far lower (32p today) - it seems that late October has brought on the Spectre of Options - - - laughingly said to be part of the incentive-plan - - - So where is mine? - all I recall is the sp slipping and prior promises left hanging in the air.
This sp was well over 1 not that long ago. Promises of a cure for obesity looked good, but they were reluctant to sell anything, preferring to do a deal with Big Pharma - ah yes, but I suspect BP found the stuff was too expensive, so they had to do a deal with a "foodie" - - and as far as I know that has been very silent.
Grr.

EDIT. Dec.'07:-
I read that things are progressing, but there seems to be little interest here/elsewhere, as this is a long-time event. The dog-treatment is doing OK and the Food additive looks to be undergoing trials, still.

hangon - 29 May 2008 16:55 - 45 of 94

Not much to report beyond the EDIT of Dec 07.....
-Apart from a fundraising at 22p - quite dilutive! (March 2008).

-and within two months we are seeing the sp matching the Discounted Rights Issue......Oh no, is this another bad investment?
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