What is a "food-derived bioactive technology" and a "functional food"?
It is becoming increasingly accepted by the scientific community that there are links between specific food groups and their capacity to help reduce the risk of certain diseases. For example, some compounds specifically found in broccoli have been shown to reduce the risk of some cancers. Consuming the actual food may be insufficient to maximise the health benefit due to a number of factors including: the quantity of the food that would need to be consumed; the frequency with which it would need to be consumed; and the way in which the food is prepared prior to consumption.

These health-promoting compounds can be extracted from the food source (called a food-derived bioactive technology) and reintroduced into consumer-friendly lifestyle products which are proven to maintain health (a functional food). Therefore, instead of eating four large servings of broccoli per week, the same benefit may be technically delivered via a 250ml orange juice drink containing the bioactive if consumed once per week.

How is Provexis differentiated from other companies in the market?
Provexis is an evidence-based business which means that we only develop food-derived bioactive technologies and functional food products that have been scientifically proven to deliver a health benefit. This is a different approach from those that promote functional food products in a more generic way with less scientific evidence. We believe that functional food products with strong scientific proof carrying health claims and endorsements will endure and prosper as this rapidly growing market matures.

Provexis is also differentiated with regard to our speed-to-market credentials and the fact that we can create shareholder value via a combination of technology licensing and own brand development.

What food-derived bioactive technologies are being developed by Provexis?
Provexis has developed Fruitflow, a patented extract from tomato that has been proven to inhibit blood platelet aggregation, thereby reducing the risk of thrombosis. A thrombosis is an aberrant blood clot that can lead to heart attack and stroke. Provexis has integrated Fruitflow into a fruit juice beverage called Sirco. When launched - initially in the United Kingdom - it will be the first functional food carrying the claim Helps maintain a healthy heart and benefit circulation with a measurable benefit within hours of consumption.

Provexis is developing a proprietary extract from a special breed of broccoli (non-GMO) which is enriched in compounds known to reduce the risk of specific cancers. Provexis intends to use this food-derived bioactive to underpin a new range of functional beverages with scientifically proven protective properties.

In addition, Provexis is developing a patented extract from plantain with a view to developing a novel medical food for the dietary management of Inflammatory Bowel Disease, specifically Crohns Disease in the first instance.

From me - nice strength shown today intra-day, relatively low sell volumes today, most people in for the launch. Think this will rise for the last 2 days of the week and possibly form a new high.

From the company secretary.

Sirco will be available in Sainsburys from the second week in January in the chilled juice section, and will be available in Waitrose stores from 25th January. Unfortunately, at this stage I am not able to tell you which stores, until the retailers confirm this information with us.

Provexis PLC
09 January 2006


9 January 2006

PROVEXIS PLC
('Provexis' or the 'Company')

Further Major Distribution Agreement for SircoTM

Provexis, the nutraceutical company that develops scientifically-proven
functional and medical foods, announces a further distribution agreement with a
market leading supermarket chain for its SircoTM heart health juice drink.

From February 2006, SircoTM Blueberry & Apple variety will be stocked in
approximately 200 of this supermarket's key premier stores bringing the total UK
distribution base for SircoTM to over 500 stores by the end of February 2006.

Further to the Company's announcement released on 16 December 2005, SircoTM is
now available in 211 Sainsbury's stores and is expected to be available in 100
stores of the second multiple supermarket chain from 23 January 2006.

SircoTM is the first heart health product to contain the patented FruitflowTM
technology. FruitflowTM was developed by Provexis in order to help regular
'healthy' consumers reduce the risk of heart attack and stroke. The natural
bioactive works by reducing blood platelet aggregation ('thinning the blood'),
a significant contributing factor to a thrombosis (internal blood clot). SircoTM
carries the health claim 'Helps to Maintain a Healthy Heart and Benefits
Circulation' and is approved by the leading heart health charity, HEART UK.

Commenting on the expanded distribution, Dr Stephen Franklin, CEO of Provexis,
said:

'We are delighted to have secured a listing with a third major retailer. The
distribution base of SircoTM is expanding on schedule and will be sufficiently
established to maximise the nationwide, multimedia, advertising campaign which
will run throughout the Spring and early Summer'.

For further information please contact:

Provexis plc
Dr Stephen Franklin 020 8392 6631

Bell Pottinger Corporate & Financial
Ann-Marie Wilkinson/Emma Kent 020 7861 3232

looks like everything is going to plan.

Provexis PLC
17 January 2006


PROVEXIS PLC ('the Company')

17 January 2006

DIRECTORS' DEALINGS

On 16 January 2006, the Board of Provexis plc approved the grant to Directors of
options over ordinary shares in the Company under the Company's 2005 Share
Option Scheme, exercisable at 8.62p per share, any time between 3 and 10 years
of the date of grant, as follows:

Director Options granted Total Options held following Grant

Stewart Slade 2,088,167 2,088,167

The options are exercisable between 3 and 10 years from grant.

so far , so good. pxs has been nicely moving in the right direction. the product is now out on supermarket shelves. i would imagine that the company will soon be giving an indication of how sales are going.

it just gets better and better.

"Provexis PLC
23 January 2006


PROVEXIS PLC
('Provexis' or the 'Company')

Significant Increase in Number of Distribution Outlets for SircoTM

Provexis, the nutraceutical company that develops scientifically-proven
functional and medical foods, announces a significant increase in the number of
distribution outlets for its SircoTM heart health juice drink, under the terms
of its most recent distribution agreement with a market leading supermarket
chain.

Further to the Company's announcement of 9 January 2006 detailing its third
distribution agreement, SircoTM will now be available in 550 of this retailer's
stores from 30 January 2006, representing an increase of 350 outlets. Sirco is
now available in 211 Sainsbury's stores and will be available in 123 Waitrose
stores from 23 January 2006. This will bring the total UK distribution base for
Sirco to 884 stores by the end of January 2006.

SircoTM is the first heart health product to contain the patented FruitflowTM
technology. FruitflowTM was developed by Provexis in order to help regular
'healthy' consumers reduce the risk of heart attack and stroke. The natural
bioactive works by reducing blood platelet aggregation ('thinning the blood'), a
significant contributing factor to a thrombosis (internal blood clot). SircoTM
carries the health claim 'Helps to Maintain a Healthy Heart and Benefits
Circulation' and is approved by the leading heart health charity, HEART UK.

Commenting on the expanded distribution, Dr Stephen Franklin, CEO of Provexis,
said:

'We are delighted to have received this substantial increased commitment from
the third major retailer prior to the date of its planned launch. Our focused
media campaign to consumers is scheduled to commence on 21 January 2006 and our
sales support activities have been in effect since 10 January' "

can't believe the lack of interest in this.

check the AFN board. there are more followers in PXS there.

ecomkid, there were some on here , but they seem to have disappeared just as things are getting interesting.

unreal!!!!!!! come on baby!!!

bos
I have this on my watch list it's doing well

driver, just a little ;)

still no interest ? as long as the drinks sell there really isn't too much downside to this. there's still a raft of outlets for pxs to target. that could mean a steady flow of news about new outlets and then hopefully some good sales figures announcements.

lovely rise here ,too :)

Hi. Have been accumulating for a while. Big potential here IMO. V little downside for health products at the moment + some big distribution deals in the pipeline apparently.

down today. no reason why that i can see, but , then again, it can't really go up everyday :)

Fell on v low volume. ??

No interest here!!

I see from the provexis website that the products will be selling in 884 outlets in the UK by end of jan '06. EOY is 31.03.06 so the figures should be positive. We shall see. (.6mfor 04/5)

From 23.01.06

Provexis, the nutraceutical company that develops scientifically-proven functional and medical foods, announces a significant increase in the number of distribution outlets for its Sirco heart health juice drink, under the terms of its most recent distribution agreement with a market leading supermarket chain.

johnny, that's already been posted. not much to do or say for the time being except wait for some figures or news about new distribution agreements.