DYOR! (Comments?)

gild18er
Have you got a stop-loss in place?
I fear that on no news these will fall even further. I am watching from the side-lines to buy in but don't want to catch a falling knife. On balance I believe in their 'story' but further drastic falls may force their hand to make an announcement more substantive than their last one. And when will that be? Tomorrow, or days, weeks, months? Thats the uncertainty of it all.
If you are over 30% down then IMHO I'd hold and ride it out. If less perhaps sell and try and get back in at a lower price. Or a mixture of both. But then this is just my view. I'm sure others would disagree. In the end its your call. Good luck.

Gild18er, you should sell and cut your loss. Don't hold out for a bounce in the price, it may fall a lot further before it comes.

What about getting in now? Big drop and now at 122 to buy? Have not held before but just sold BGY to lock in profit - I know they're still going up but I'm chicken. Or anything better today to go for???????

amberjane
Tricky to call the floor on these at the moment, but I think if you look at the medium to long term ( but don't discount the short term)you would be getting in at a good price, and if you have faith in their story, which I do then you can ride out the current volitility. I wouldn't be suprised if they dropped more after a little rally over the next couple of days or so but wouldn't count on it. If there is very heavy buying tomorrow it could suggest the floor has been reached. My conclusion is to stay out at the moment, why take such a risk?
For another to go for try BPRG. A large contract plus broker's note is imminent and the price is relatively low at the moment. In fact if you get in tomorrow (wednesday) before it you will be lucky. We have been told by management within two weeks but rumours are flying that the brokers note is due Thursday, so the contract should (but anything can happen)be announced before or with it. I am very heavily into these. No ramp intended. DYOR.

No e-mail to contact u direct but thanks, what price is good for BPRG today, don't have level 2, abowt 113?

OT
amberjane
113 is good at this stage IMHO. 110 has proved a good support in the recent past so its not too far off. Some on another BB think maybe early next week if not this week for Brokers note and contract so don't panic if its not out by Friday. All rumours etc to be treated with a healthy pinch of salt! Its close though. Are you aware of the another BB starting ADV..? Good threads there on BPRG and research website given in the header of the main one. If you can't access the BB the research web page is: http://mysite.freeserve.com/bprg/index.html
Good luck

Many thanks, will consider. Ta

Well did my research and decided, went to buy and after my first quote at 114 upped the amount & it went to 116 :-{{{{

Oh sorry, excellent for all you holders. Luv me x

Hope you have called the bottom right Amberjane but fear its got further to fall. Guess we will know tomorrow. I got out yesterday.

I consider 105 to be a good bounce off point...still a bit worried as it might fall further as Antisoma did a couple of days ago but I reckon 105p will offer good support..

Yes agree mitzy, now I've had excellent training on how to read charts and work out what they mean! 105 would be good price to buy in at. Perhaps I should have put this on the right thread, sorry if I'm confusing anyone, had a strange e-mail. x

Crikey, still free-falling this morning. I pity the poor blighters still holding. One thing though, there is going to be one massive bounce back up when it comes. Are you ready?

Biotech stocks being further derated, risk premuim being reduced.

It has gone right through 105p - its support point - and i think it will be falling right to 65-75p in the next few days. STRONG SELL!

Somebody keeps buying...There were rumours of a take over some time ago at 5. Who would not accept 1.50 now ?

I think (hope) the bottom has been reached and bought back this afternoon

Proteome at its highest worth only 2.40 in 1998. Nobody would offer 5 for it. It is a SELL.

From HODBOD on ADVFN -
I have not posted on this thread before. I have held shares in PRM since early 2001 having become aware of the Company through the bulletin board.In spite of the confidence shown by some fellow investors and the detailed reasoning that leads the bulls to the development of financial forecasts that justify huge future valuations for the Company,I have not changed the view I formed when I bought the shares. PRM are a highly speculative investment that may in time yield high returns because the Company is in at the early stages of a new technology that promises the prospect of exponential growth for those Companies that are sucessful. However, there is a higher probability that PRM will fail to develop as a major company and may even fold up because that is the nature of the process by which high tech tadpoles turn into mature financially successful frogs.

New technology is exciting but it is extremely difficult to make forecasts about the commercial prospects for any particular piece of IP especially when it is in the hands of a small developing company.

Adopting the analogy of the computer industry, in 1990 there were zillions of companies that were developing both hardware and software that was mind boggling in terms of its superiority over the technology that existed in 1980.However, relatively few of them developed into major companies because the challenge of commercialising their technology was beyond the capabilities of the company, or the technology was not competitive compared to developments that were taking place simultaneously in other companies and that would not become public knowledge until the competition judged the time was right to launch it.

PRM have some exciting IP. What that means in terms of the future fortunes of the company and the share price depends to a great extent on what is happening elsewhere as well as on how well managed PRM itself is. It is also imperative that the small investor does not lose sight of the fact that this is a small company and that neither the financial markets or the large players in the biotech industry are going to be anything other than ruthless in trying to take advantage of a small vulnerable company if the opportunity arises.

Don't blame the management because they can't fulfill your dreams on the day you require them to be fulfilled. Have the maturity to recognise that we are all seduced by the prospect of having a dream come true,especially if it could have happened by April 9th. Take this opportunity to reassess the realities of the situation and decide whether this is a share in which you should be investing Personally, I still feel that there is enough substance in the company to justify risking my entire stake, but I acknowledge a significant probability that they could return to the price atwhich I purchased them or they might even become worthless.

To the people who have genuinely given me the benefit of their knowledge and insights I offer my thanks whether they seek to argue that the company is bound for huge success or put forward carefully crafted explanations as to why they feel that such optimism is misguided. You have all provided me with a base from which I could make my own judgements and exercise my own instincts.Please continue to provide me with informed opinions. I accept them as opinions and nothing more or nothing less.

As for the people who seek to undermine confidence in the company and warn that doom is around every corner, I must recognise that they are playing a different game and accept them as a fact of life. It is as pointless to complain about them as it is to complain about the existence of gravity.
However, I would add that posters like NNN who merely scream banalities and do not feel that the rest of us are worthy of the courtesy of a reasoned argument do try my patience. If my prayers are answered their extremities will rot.

I feel that the next 12 months is a critical period for my investment in PRM. To date I have been interested and patient, but 12 months ago there was a significant change in the declared prospects for the Company when the Management gave strong indications that commercialisation of IP was on the horizon, if not immminent. Given the nature and complexity of IP licencing I can understand that precise timing is difficult. However, unless there is confirmation of actual revenue generating deals before the end of 2004 it will be hard to avoid the conclusion that there probably is no end to this particular rainbow.

Market Report: Bear raiders make profits on Proteome Science
By Michael Jivkov
30 April 2004


Bear raiders moved in on the biotech group Proteome Science yesterday and, given the stock's dramatic 19 per cent slide, they look to have made a packet. The raiders are believed to have noticed some time ago that there were a large number of private investors holding the stock via contracts for difference.

These allow investors to gain exposure to, say, 100,000 worth of shares in Proteome, but only put up a fraction of the money in hard cash. This means that private punters can turn a relatively small amount of money into a lot more. But it also means that when a position goes the wrong way for an investor he can quickly find himself nursing a large loss and being urged by the broker offering him the contract for difference to close his position and sell out.

This is what many private punters were forced to do yesterday as bear raiders pushed Proteome shares lower. And the further they fell, the more punters were forced to close their positions, which in turn pushed the group's shares even lower. They ended the day 21p lower at 88.5p.

Proteome's stock has halved over the past month but market professionals believe it is unlikely to fall any further, noting that nothing has fundamentally changed at the group during this period. Among them was Evolution Beeson Gregory. The broker reiterated its "buy" rating on Proteome and tipped newsflow from the company in the near future to help rally its shareshttp://news.independent.co.uk/business/analysis_and_features/story.jsp?story=516595

UK smallcap opening - Proteome Sciences rally after reports of CFD pressure
Fri 30 Apr 2004 08:33

LONDON (AFX) - Shares in Proteome Sciences rallied by 6 pct in opening
trade, having fallen 19 pct yesterday amid reports the stock was being squeezed
by trading related to a large spread-betting contract known as a contract for
difference (CFD).
According to the Daily Mail, market-maker Winterflood took out a CFD
contract with IG Index then marked the stock down to attract buyers. However,
buyers failed to materialise, the newspaper reported.
Other newspapers suggested that yesterday's fall had triggered margin calls
on holders of CFDs on the drug developer, who have been caught in a downward
spiral.
At 8.14 am, shares in Proteome were ahead 5 pence to 93-1/2.

Janus,

Thank you for your sensible posts. Made me think about several tiny shares I've been chasing recently and losing sleep over.

I aggree wholeheartely about NNN & co.