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PROTHERICS (PTI)     

WHITESTAR001 - 10 Feb 2006 15:08

THIS SHARE WILL BE WORTH 3.00 IN 2009

greekman - 03 Nov 2006 11:49 - 59 of 309

Opened lower as the MM's knew that most punters would look at it as more delay, but it's not bad news. The drug industry is not a get rich today, tomorrow or even next year.
Patience is the key. Protherics must be one of the best up and coming companies in it's field. If things progress as expected, todays sp will be looked back on as a fantastic bargain. It also as stated has other products progressing nicely.

Following is an extract from a Market-wire. CytoFab, Voraxase, Prolarix, CroFab, (pit viper antivenom) and DigiFab are also mentioned.

CytoFab is a first in class anti-TNF-alpha polyclonal antibody fragment (Fab) product, which is being developed for the treatment of severe sepsis.

The most advanced products in the Company's portfolio are Voraxaze, which is expected to be approved in the US and EU in 2007, subject to regulatory reviews, as an intervention when methotrexate blood levels remain dangerously high following high doses for the treatment of cancer and CytoFab, which is being developed by AstraZeneca, initially for severe sepsis, and is expected to start an additional Phase II study in 2007.

See link for full article, it's well worth a read to reiterate what a forward looking company Protherics is.

If I had spare cash, I would be looking at this drop in the sp as a buy opportunity.

http://www.marketwire.com/mw/release_html_b1?release_id=180059

bristlelad - 03 Nov 2006 12:52 - 60 of 309

Iam glad that Iam not the only person who has overspent on s.e.o so have no money left to buy these at this price /Ihope we have done the right thing///

greekman - 07 Nov 2006 09:20 - 61 of 309

Protherics to resubmit its Voraxaze(TM) BLA following FDA data request.
Still looking good for Voraxaze, but any delay is bad news even if it appears to be only 6 months (a small time in the drug world).
This looks worse than it is probably due to being on the back of the previous RNS.
Shares look a good buy at this price, as long as a term of at least 1 to 2 years is being looked at.

hlyeo98 - 07 Nov 2006 09:22 - 62 of 309

There will be further downtrend in the short term...IMO to 60p

hlyeo98 - 07 Nov 2006 16:10 - 63 of 309

Chart.aspx?Provider=EODIntra&Code=PTI&Si

greekman - 07 Nov 2006 16:24 - 64 of 309

Hlyeo,

Could be right but I think the drop has been overdone, they usually are.
I expect it to end the week still down but with some recovery.

queen1 - 07 Nov 2006 19:55 - 65 of 309

The drop has been well overdone. We're in the same place we were this time yeasterday, just 6 months further away. Not a justification for such a large drop. This will definately bounce back.

hlyeo98 - 08 Nov 2006 00:13 - 66 of 309

but delays in product coming onto the market means loss of income. I think it will go lower.

greekman - 08 Nov 2006 07:30 - 67 of 309

Agree it means income coming in later (about 6 months) but if you look at the whole picture, did this delay warrant a drop of that percentage.
They have other products already producing income. Their financial situation is also good. They have a good R+D set up, excellent management and a health product line.

kimoldfield - 08 Nov 2006 08:08 - 68 of 309

The Independent has Protherics as a buy

"Investors should use the recent weakness in Protherics stock, due to delays two drugs under development, as a buying opportunity.The company is among the most well-financed in the biotechnology sector. While via CytoFab, it, and partner AstraZeneca, pretty much have the 4bn sepsis market to themselves."

greekman - 08 Nov 2006 08:16 - 69 of 309

Hi Kim,

Nice little write up. Says it all really.
The way this day has started looks like punters are doing just that (a buying opportunity.).

kimoldfield - 08 Nov 2006 08:27 - 70 of 309

Hi GM, I'm hoping this won't be as stressful as SEO!!!
kim

greekman - 08 Nov 2006 08:53 - 71 of 309

Kim,

I would think that would be impossible, ( I hope).

queen1 - 08 Nov 2006 22:19 - 72 of 309

Well there was a bounce today as I predicted. More to come tomorrow?

greekman - 17 Nov 2006 07:37 - 73 of 309

http://www.cnw.ca/fr/releases/archive/November2006/16/c5550.html

Scrip Awards
LONDON, Nov. 16 /CNW/ - "It is only the second year, but the world now
has Scrip Awards written on its heart 600-plus international guests attended the second Scrip Awards ceremony, held at the Grosvenor House Hotel in London.


Well we all thought it was a good deal between Protherics and AstraZeneca, now it looks better than ever. This lot presumably know what they are on about.
Anything such as this bring PTI more into the public but mainly the private eye view of the pharmaceutical industry.
All the big names were obviously there. It must me like the Oscar Awards for the drug industry.
The whole article is not very interesting but if you want a look, see link.

Licensing Deal of the Year
Sponsored by Imperial Innovations
Winner - Protherics and AstraZeneca
For those who remember the deal was announced on 8th December 2005.

queen1 - 17 Nov 2006 12:30 - 74 of 309

A ringing endorsement greekman. Let's hope this helps to settle investors nerves that have been jangling a little over the past fortnight.

greekman - 17 Nov 2006 13:09 - 75 of 309

Hi Q,

I think it will as it already appears to have calmed down somewhat.
No matter what the share there are always those interested in a quick buck (me included), but Protherics is one to put away for 1 to 3 years.
Obviously in the drug business, as we know no matter how well trials are going, it can go wrong at the last hurdle.

queen1 - 17 Nov 2006 20:23 - 76 of 309

Indeed. But like you I'm squirreling away for that sunny day :-)

greekman - 27 Nov 2006 07:33 - 77 of 309

RNS with excellent news.
It looks like DigiFabTM is a great improvement on Roche's Digitalis Antidote(R).
Also with a nice close working relationship with Roche, it makes an even more viable future for PTI. Roche AND AstraZeneca.
Protherics is now really playing with the big boys.

petralva - 27 Nov 2006 08:33 - 78 of 309



Protherics PLC
27 November 2006

Protherics PLC

Protherics' DigiFabTM to replace Digitalis Antidot(R) in Europe


London, UK; Brentwood, TN, US: 27 November 2006 - Protherics PLC ('Protherics'
or the 'Company'), the international biopharmaceutical company focused on
critical care and cancer, today announces the transfer of market rights for
Digitalis Antidot(R) from Roche to Protherics, with the intention of replacing
Roche's Digitalis Antidot(R) in the market with Protherics' own digitalis
antidote DigiFabTM from early 2007.

Roche's Digitalis Antidot(R) is currently approved in France, Germany and
Switzerland. Protherics has acquired the market rights for Digitalis Antidot(R)
for a small undisclosed cash consideration, and is working with Roche to
facilitate the smooth transition in the market from Digitalis Antidot(R) to
DigiFabTM.

DigiFabTM is an ovine derived Fab preparation for the treatment of digoxin
toxicity which can have severe effects on the heart and central nervous system,
sometimes leading to death. It is currently licensed by the US Food and Drug
Administration for the treatment of patients with life-threatening or
potentially life-threatening digoxin toxicity or overdose. Marketing
authorisation will be sought in major European countries, including France,
Germany, Spain and Italy, following grant of approval in the UK, expected early
in 2007. Protherics will continue to make DigiFabTM available on a named
patient basis.

DigiFabTM will be marketed in most mainland European countries by Protherics'
licensee, Beacon Pharmaceuticals. Protherics will be directly responsible for
marketing and sales in Germany, one of the major European markets, as well as in
the Nordic countries.

Andrew Heath, Chief Executive of Protherics said:

'Protherics' goal is to become the global market leader in the anti-digoxin
antibody market. We are pleased to be co-operating with Roche in arranging for
a smooth market transition from Digitalis Antidot(R) to DigiFabTM in order to
ensure continued patient care for this potentially life-threatening condition.'

Eugene Tierney, Business Director at Roche said:

'Roche has been looking for a company that can take over its digitalis antidote
business, to ensure that it remains available for patients to treat
intoxication. We are pleased that Protherics, a company experienced in that
business, will be supplying the market.'





For further information please contact:


Protherics
Andrew Heath, CEO +44 (0) 20 7246 9950
Nick Staples, Director of Corporate Affairs +44 (0) 7919 480510
Saul Komisar, President Protherics Inc +1 615 327 1027

Financial Dynamics - press enquiries
London: Ben Atwell, David Yates, Anna Keeble +44 (0) 20 7831 3113
New York: John Capodanno, Jonathan Birt +1 212 850 5600


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