What is a "food-derived bioactive technology" and a "functional food"?
It is becoming increasingly accepted by the scientific community that there are links between specific food groups and their capacity to help reduce the risk of certain diseases. For example, some compounds specifically found in broccoli have been shown to reduce the risk of some cancers. Consuming the actual food may be insufficient to maximise the health benefit due to a number of factors including: the quantity of the food that would need to be consumed; the frequency with which it would need to be consumed; and the way in which the food is prepared prior to consumption.

These health-promoting compounds can be extracted from the food source (called a food-derived bioactive technology) and reintroduced into consumer-friendly lifestyle products which are proven to maintain health (a functional food). Therefore, instead of eating four large servings of broccoli per week, the same benefit may be technically delivered via a 250ml orange juice drink containing the bioactive if consumed once per week.

How is Provexis differentiated from other companies in the market?
Provexis is an evidence-based business which means that we only develop food-derived bioactive technologies and functional food products that have been scientifically proven to deliver a health benefit. This is a different approach from those that promote functional food products in a more generic way with less scientific evidence. We believe that functional food products with strong scientific proof carrying health claims and endorsements will endure and prosper as this rapidly growing market matures.

Provexis is also differentiated with regard to our speed-to-market credentials and the fact that we can create shareholder value via a combination of technology licensing and own brand development.

What food-derived bioactive technologies are being developed by Provexis?
Provexis has developed Fruitflow, a patented extract from tomato that has been proven to inhibit blood platelet aggregation, thereby reducing the risk of thrombosis. A thrombosis is an aberrant blood clot that can lead to heart attack and stroke. Provexis has integrated Fruitflow into a fruit juice beverage called Sirco. When launched - initially in the United Kingdom - it will be the first functional food carrying the claim Helps maintain a healthy heart and benefit circulation with a measurable benefit within hours of consumption.

Provexis is developing a proprietary extract from a special breed of broccoli (non-GMO) which is enriched in compounds known to reduce the risk of specific cancers. Provexis intends to use this food-derived bioactive to underpin a new range of functional beverages with scientifically proven protective properties.

In addition, Provexis is developing a patented extract from plantain with a view to developing a novel medical food for the dietary management of Inflammatory Bowel Disease, specifically Crohns Disease in the first instance.

ewrobson if you go on to sirco website it will tell you where you'r nearest store is .if i remember, they e mailed it to me.

FYI - a "dildrum" is something you can play with in private when life is dull!

sd The mind boggles, even bogdrums! Now life is not dull with PXS. It opens up fantasies, not of nubile young ladies like ASC, but of soaring bank balances whilst the population gains longevity. But its difficult sussing what the cap should be wothout any numbers. I just have the gut feel that this will go reasonably quickly to 100m. Impressed by the people with a lovely Lucozade person lading the marketing.

Eric

Sirco has just appeared in our local tesco's (Weston Favel, Northampton) Have yet to checkout the other stores in the area but doubt if the others are not stocking as well. There does not appear to be any specific promotion but there are a few gaps on the shelves.

Looking good.

tesco too? what happened to the 2.5 million they were going to spend on the advertising and promotion campaign. not seen nuffink, yet!!!!

Perhaps the promotion will start when all the participating stores are stocked up?

our local tesco in hucknall, notts was sold out on sat; morrning..look's good to me.. hope they can keep up with production,so we can keep up with the share price !!!!

absolutely fantastic news.

Provexis PLC
09 March 2006


PROVEXIS PLC

('Provexis' or the 'Company')

FruitflowTM has GRAS status affirmed in the United States

Provexis, the nutraceutical company that develops scientifically-proven
functional and medical foods, announces that an independent Expert Panel in the
United States has affirmed FruitflowTM to be Generally Recognised as Safe
('GRAS'), paving the way for products containing FruitflowTM to be marketed in
the United States and Canada.

The Expert Panel agreed that the components of FruitflowTM have a long history
of consumption as part of the normal diet and would be consumed at levels that
are comparable to those that are possible from the consumption of other
tomato-based food products. Furthermore, clinical studies have demonstrated that
FruitflowTM is without adverse effects and well-tolerated.

In the United Kingdom, SircoTM heart health juice drink is the first heart
health product to contain the patented FruitflowTM technology. FruitflowTM works
by reducing blood platelet aggregation ('thinning the blood'), a significant
contributing factor to a thrombosis (internal blood clot) which can lead to
heart attack or stroke. SircoTM, which was launched in the UK in January 2006,
is currently available in selected Tesco, Sainsbury and Waitrose stores.

The GRAS affirmation of FruitflowTM is a significant development for Provexis as
it continues to implement its strategy of commercialising FruitflowTM in the
United States by securing licensing arrangements with global food and drink
corporations. A Mintel report published in August 2005 estimated the market for
heart healthy products in the US was worth $18.7bn and this market is forecast
to grow by 16% by 2010.

Commenting on the news, Dr Stephen Franklin, CEO of Provexis, said:

'We are delighted that FruitFlowTM has been affirmed GRAS as this represents the
essential precursor to unlocking the substantial commercial opportunities
available in North America. With our existing clearance in Europe, we now have
access to our two primary target markets which we intend to realise via our
licensing strategy.'

Another step forward. Huge market in states & canada. Great news.

jtf

been watching and reading for a while and bought in this morning on news...should have known better given the quality of the posters here and bought in earlier but....



GN

Global, Hi. Better late than never. Topped up myself today. Still time to accumulate imho.

Good luck

jtf

http://www.fruitflow.info/

Some interesting info here regarding product & promotion.

jtf

Thanks, bos: fuller quote than on the AFX. Still haven't seen any financial data. Happy its a winner and have an exploratory investment. Just found out from blueindex that they are prepared to cover with CFDs.

Eric

"A Mintel report published in August 2005 estimated the market for
heart healthy products in the US was worth $18.7bn and this market is forecast
to grow by 16% by 2010."

i think that sentence on its own is enough to give you palpitations !!!! it is really difficult to find a downside to this share , as long as the product actually sells.
opposing views appreciated just to stop us rampers getting carried away :)

did anyone else see the news of reports in the last week associated with britvics decline about the rapid change in eating habits? including huge rises in proboitic sales etc in the Uk, decline in sales of readymeals, increase in fruit and veg sales...

all points to a consumer change which is happy with enhanced food stuffs and healthier eating.

GN

Not in but looking good PXS has been promoted to Drivers Tips.

thanks for the product placement.....

Bos, have been trying to find a downside here but yet to find one. The packaging certainly looks appealing/attractive. That's usually the main initial selling point but it's the repeat sales that will really boost the figures. I don't know what it tastes like (have to get down to my local Tesco) but if it tastes as good as it looks?
JTF

http://www.sircoheart.com/

http://www.fruitflow.info/

cheers , jtf.

What is the unit price? Noticed earlier release statement about larger container being on market by mid year. How many is each store stocking and can we deduce the sales volume? Anything else to help with projections re Sirco sales values. Agree bos re the huge size of the US market in particular. Happy to be in, even in a small way.