About ERIX
EiRx Therapeutics is a specialist provider of pre-clinical therapeutics to the pharmaceutical industry. Our unique scientific expertise and knowledge in the field of Apoptosis provide a sound base to discover and develop new medicines that will safely and selectively repair this natural process in disease. The potential benefits from these new medicines are enormous, since as many as 70% of all human disease have some defect in the control of Apoptosis.
Apoptosis - the biological process that determines whether cells in our bodies live or die...
http://www.eirx.com/index.html

Purchased some of these on the strength of the PROGRESS UPDATE looks promising.
http://moneyam.uk-wire.com/cgi-bin/articles/200603200701130254A.html

ERX interview with John Pool
http://www.wallstreetreporter.com/interview.php?id=18589&player=real
Latest News
CANCER COLLABORATION WITH BIOMERIEUX SA
http://moneyam.uk-wire.com/cgi-bin/articles/200607120700230534G.html
Biomerieux Web Site
http://www.biomerieux.com/servlet/srt/bio/portail/home
ABOUT ERX Focus Of The Month
http://www.billamag.net/focus-document-text.asp?FocusTextID=1
ERX pdf filehttp://www.eirx.com/eirx_heading_images/Yokohama2005.pdf
19/09/2006 A 50% reduction in breast tumour volume size seen with Eirx lead molecule in animal studies
http://moneyam.uk-wire.com/cgi-bin/articles/200609190700171175J.html

Past and present collaborative partners include:

* bioMieux SA
* Almac Diagnostics Ltd
* Merck & Co, Ltd
* Biofocus plc
* MGI Pharmaceuticals, Inc
* OSI Pharmaceuticals, Inc
* Sareum plc
* Regen Therapeutics plc
* SR Pharma plc

POST OF THE DAY!!!!

PH is still posting on our thread, so he hasn't sold yet.

THIS IS THE BIT I LIKE IN THE ABOVE EMAIL

"We are not considering going back to the market, if at all, without some very
significant news"

ph
Have a nice weekend.

you too...

xxx ;-) both cheeks

should be a good week by all counts

will let you know Friday :)

PH, didnt Henry Ford make cars as long as they were black.

MOST INCONVIENIENT IF THEY ANNOUNCE ON FRIDAY, BEEN INVITED TO A CHRISTMAS DO.. STARTS AT MID-DAY ;-(

Note:


we have news on one of our patents... YYYIIIIIIIIIIPEEEEEEEEEEEEE

7 SURVIVIN in my patents list
Inventor: HAYES IAN (IE); COTTER TOM (IE); (+5) Applicant: EIRX THERAPEUTICS LTD (IE); HAYES IAN (IE); (+6)
EC: C07K14/47A1A; C07K14/47A33 IPC: C07K14/47; A61K38/00; C07K14/435 (+2)
Publication info: WO03091384 - 2003-11-06


read the link

Lilly Highlights Two Collaboration Drugs in Its Pipeline Update
PR Newswire (press release), NY - 22 hours ago
- Plans Broad Phase 2 Cancer Trials for Survivin ASO to Begin Late in 2006 and 2007 - CARLSBAD, Calif., Dec. 11 /PRNewswire-FirstCall ...

http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-11-2006/0004488564&EDATE=


Look at patent list for Eirx re: SURVIVIN patent number 7

http://v3.espacenet.com/results?sf=a&FIRST=1&CY=gb&LG=en&DB=EPODOC&TI=&AB=&PN=&AP=&PR=&PD=&PA=eirx&IN=&EC=&IC=&=&=&=&=&=

http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-11-2006/0004488564&EDATE=
ABOUT LY2181308 AND SURVIVIN
LY2181308 targets survivin, a molecule that supports the survival of
cells that would normally die through programmed cell death or apoptosis.
Survivin helps in the abnormal growth of cancer cells, and is abundant in
many types of cancers, including colon, brain, lung, skin and others, but
nearly nonexistent in normal cells and tissues.

-------------------------------------------------------------------------------------------------------------

http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-11-2006/0004488564&EDATE=
7 SURVIVIN in my patents list
Inventor: HAYES IAN (IE); COTTER TOM (IE); (+5) Applicant: EIRX THERAPEUTICS LTD (IE); HAYES IAN (IE); (+6)
EC: C07K14/47A1A; C07K14/47A33 IPC: C07K14/47; A61K38/00; C07K14/435 (+2)
Publication info: WO03091384 - 2003-11-06

-------------------------------------------------------------------------------------------------------------
CARLSBAD, Calif., Dec. 11 /PRNewswire-FirstCall/ -- Isis
Pharmaceuticals, Inc. (Nasdaq: ISIS) announced today that Eli Lilly and
Company (NYSE: LLY) highlighted two antisense oligonucleotide (ASO) drugs
in its "Update to Wall Street on Strategic Priorities and Pipeline
Progress" on Thursday. Advances with both survivin ASO (LY2181308) and
eIF-4E ASO (LY2275796) drugs were singled out among Select Early- to
Mid-Stage Pipeline Developments. Based on promising activity in early
studies, Lilly said that it is initiating Phase 2 trials for survivin ASO
in a broad range of cancers including liver cancer, prostate cancer, acute
myelogenous leukemia, ovarian cancer and non-small cell lung cancer; the
first of these trials is planned to begin this month. Lilly also said that
the Phase 1 development program for eIF-4E ASO is progressing well.
"We are pleased that Lilly includes our collaboration drugs among its
selected strategic priorities," commented C. Frank Bennett, Ph.D., Isis'
Senior Vice President of Research. "These drugs resulted from our
productive collaboration and Lilly's broad investment in antisense
technologies. We continue to work together and hope that additional drugs
will arise from our collective efforts. Lilly's progress with these
anti-cancer drugs emphasizes the broad therapeutic potential of Isis'
platform antisense technologies, and underscores our strategy of working
with partners to expand the scope of our development pipeline.

Luckypicker - 12 Dec'06 - 12:07 - 14953 of 14956


"john"
12/12/2006 11:53
To
XXX

Subject
Re: Shareholder Question





Hi
As CEO as just returned from the US completing statements
J
------------------
Sent with Instant Email from T-Mobile

-----Original Message-----
From: XXXX
Date: Tue, 12 Dec 2006 11:51:22
To:"John K Pool"
Subject: Re: Shareholder Question

Dear John

why no RNS??






Presenting it like this would've helped - nice find though.- I believe this is worthy of RNS

http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-11-2006/0004488564&EDATE=
ABOUT LY2181308 AND SURVIVIN
LY2181308 targets survivin, a molecule that supports the survival of
cells that would normally die through programmed cell death or apoptosis.
Survivin helps in the abnormal growth of cancer cells, and is abundant in
many types of cancers, including colon, brain, lung, skin and others, but
nearly nonexistent in normal cells and tissues.

------------------------------------------------------------------------------------------------------------
-

http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-11-2006/0004488564&EDATE=
7 SURVIVIN in my patents list
Inventor: HAYES IAN (IE); COTTER TOM (IE); (+5) Applicant: EIRX THERAPEUTICS LTD (IE); HAYES IAN (IE); (+6)
EC: C07K14/47A1A; C07K14/47A33 IPC: C07K14/47; A61K38/00; C07K14/435 (+2)
Publication info: WO03091384 - 2003-11-06

------------------------------------------------------------------------------------------------------------
-
CARLSBAD, Calif., Dec. 11 /PRNewswire-FirstCall/ -- Isis
Pharmaceuticals, Inc. (Nasdaq: ISIS) announced today that Eli Lilly and
Company (NYSE: LLY) highlighted two antisense oligonucleotide (ASO) drugs
in its "Update to Wall Street on Strategic Priorities and Pipeline
Progress" on Thursday. Advances with both survivin ASO (LY2181308) and
eIF-4E ASO (LY2275796) drugs were singled out among Select Early- to
Mid-Stage Pipeline Developments. Based on promising activity in early
studies, Lilly said that it is initiating Phase 2 trials for survivin ASO
in a broad range of cancers including liver cancer, prostate cancer, acute
myelogenous leukemia, ovarian cancer and non-small cell lung cancer; the
first of these trials is planned to begin this month. Lilly also said that
the Phase 1 development program for eIF-4E ASO is progressing well.
"We are pleased that Lilly includes our collaboration drugs among its
selected strategic priorities," commented C. Frank Bennett, Ph.D., Isis'
Senior Vice President of Research. "These drugs resulted from our
productive collaboration and Lilly's broad investment in antisense
technologies. We continue to work together and hope that additional drugs
will arise from our collective efforts. Lilly's progress with these
anti-cancer drugs emphasizes the broad therapeutic potential of Isis'
platform antisense technologies, and underscores our strategy of working
with partners to expand the scope of our development pipeline.





Kind regards

get in now, financials have been completed, results imminent with lots of good news

PH - Could you elaborate on the connection between EIRx patent and the story (above) about Eli Lilly. I have read both of the links that you have given and find no connection between the two.

Eli Lilly are to work on some drugs that they developed that target SURVIVIN.

EIRx have a patent for a means of detecting apoptosis in a cell by detecting changes in the SURVIVIN polypeptide.

There is no suggestion that Eli Lilly are working with EIRx or using their patent.

It's like saying Ferrari have developed a CAR. Skoda make CARs. Oh, hello - Ferrari and Skoda are in partnership!

check the patents, read the email from the chairman, he did not deny the link, to top it all his says the results are ready

PH - Have checked the patents. Yes, they deal with SURVIVIN. But what has that got to do with Eli Lilly. Have checked their website and all recent news items concerning Eli Lilly. Guess what? No mention of EIRx anywhere.

As for the e-mail from 'the chariman':

To the question 'Why no RNS' you got the reply 'As CEO [h]as just returned from the US completing statements'

No mention of any dealings with Eli Lilly. No mention of the link to the news story in the original question to the chairman, so how could he confirm it or deny it. No evidence that this is even a genuine reply from the chairman.

oh dear... we really dont understand the patent issue do we!!!!

check the erx patent list number 7. we also have numerous collaborations vis biofocus which includes ISIS!!!

sort yourself out lad

Mike111D - 12 Dec'06 - 14:06 - 15064 of 15065


Just a quick note to say that yes Survivin does connect back to ERX and they will comment on this as appropriate in due course.

The immediate priority is to get the results RNS out which is imminent, so expect any update on Survivin to follow but only if appropriate.

As commented on by someone else earlier today, CT has literally just returned from the US, so I think you need to allow them 24-48 hours to get their house in order.

PH - Maybe I'm just thick or something. Could you please enlighten me? As I see it (read the patent) EIRx have a patent concerning the polypeptide SURVIVIN. Eli Lilly will be doing some drug trials on SURVIVIN. Where is the tie-up?

Mike just phoned JP himself, and its confirmed, it is ours.. what is wrong with you today

PH I have looked on the ERX website for a break down of the patents with no joy.
I am assuming as ERX hold the Intellectual Property Rights on Survivin any successful production would invoke Patent?