Osmetech acquired the Opti product line from Roche Diagnostics. Opti is the portable analysis technology for bloodgas and electrolytes measurement. This highly successful analyser has also taken the veterinary world by storm. IDEXX Laboratories Inc (IDXX) have entered into a ten year OEM agreement to provide the customised OPTI analysers to the veterinary field under the brand VetStat.

In September 2004 the company acquired the "OPTIgene" (Genedrive) product from MS this technology will enable OMH a strong entry point into the fastest growing market segment of DNA based diagnostics. A market that is growing at an annual rate of 20% and is currently worth $ 22 bln !

In the latest acquisition 1/7/05 Osmetech acquired Clinical Micro Sensors from Motorola PLC, OMH plans to utilise the eSensor technology coupled with OPTIgene to address the majority of existing and new tests in the genetic diagnostics market. 'CMS's diagnostic tests for cystic fibrosis and CYP450 are closest to commercial launch and OMH believes that these products have significant market potential.

Scroll & Click for Websites & Other LinksRT Mag Wall Street Reporter Interviews JW

Up Coming Events in 2006

CMS CYP450 product Launch!!!!!............................................. 2006

IDEXX critical care platform Launch!!!!!....................................2006/7....much more to follow

Click Here to Track Osmetech's Progress in the "Stocks That Could Double in 2006" Competition

More institutional buying taking place today.

Time Price Quantity Type Bid Offer Buy/Sell Total Buy Total Sell Total Unknown
25/04/06 15:11 25.0 1,000,000 O 24.5 25.0 Buy 2,024,664 238,725 5,020
25/04/06 15:18 25.0 825,000 O 24.5 25.0 Buy 2,901,664 238,725 5,020
25/04/06 10:16 25.0 500,000 O 24.5 25.25 Buy 570,031 92,432 0
25/04/06 10:24 25.0 250,000 O 24.5 25.25 Buy 970,031 95,338 0
19/04/06 16:00 24.0 250,000 O 22.5 24.5 Buy 339,399 223,584 15,000
19/04/06 19:02 24.0 250,000 B 22.5 24.5 ? 0 0 0
25/04/06 10:21 25.0 100,000 O 24.5 25.25 Buy 720,031 95,338 0
24/04/06 16:56 25.0 100,000 O 23.0 26.0 Buy 422,530 171,071 305,000

Link

copycat

(lol)
There's an ascending triangle pattern occurring. So when 25p breaks the move to 30p should be even more rapid.
Ascending triangles
free stock charts from ADVFN.COM

I am a holder in OMH and have been for many years, I hope they do break upwards, but your chart shows 3 ascending triangles the first 2 break down !

Lets hope it's third time lucky then. Looking at yesterdays trades someone feels confident!

So it was UBS AG that were buying. Looking good!Osmetech PLC
26 April 2006

Osmetech plc ('Osmetech' or 'the Company')



The Company was notified, on 25th April 2006, that UBS AG has an interest in
8,825,000 ordinary shares of 0.1 pence each in Osmetech.

The total holding represents approximately 6.70 per cent of the Company's issued
ordinary share capital.

IDEXX Laboratories First Quarter 2006 Earnings Conference Call
Friday, April 28, 2006 - 9:00 AM ET

(Might give an update on VetStat sales and progress of CC platform)

AGM Statement

RNS Number:3112C
Osmetech PLC
03 May 2006





3 May 2006



Osmetech plc - AGM Statement

Osmetech plc, the international healthcare diagnostics group will provide the
following update during its Annual General Meeting at 11:00am today:

Critical Care Division

Our Critical Care business continues to build on the sales growth achieved in
2005 and as expected, demand in the current year for the Division's OPTI range
of blood gas analysis products has remained strong in both the human and
veterinary markets.

For the remainder of 2006 we expect the healthy levels of demand in the Critical
Care Division to continue and therefore be another year of growth for this
division.

Molecular Diagnostics Division

Osmetech continues to make significant progress and remains on schedule with its
new product launches. As planned, in March we launched our FDA approved eSensor
Cystic Fibrosis Carrier Detection test and eSensor 4800 DNA Detection instrument
and later this month we will launch our OPTI TUBE product for use in the Roche
LightCycler as a cost-effective and safe alternative to the Roche glass
capillaries. Our OPTI GENE instrument and proprietary consumable system for the
rapid detection of DNA and RNA targets will be available for sale in June,
although the product will be fully launched with thrombophilia assays at the
American Association of Clinical Chemists (AACC) Conference in Chicago in July.

We have been delighted with the initial stages of product commercialisation in
this fast growing market sector. We plan to replicate the successful Critical
Care business model of selling instruments and proprietary tests primarily to
small and medium sized hospitals across the globe through our well established
distribution networks.

The installation of instruments will provide the basis of future revenues by
introducing a wider range of tests, developed both by Osmetech and third
parties. In addition, our instruments have significant potential in other
markets, such as veterinary, environmental and forensics, which we would look to
exploit through strategic partnerships.

Outlook

The Board remains confident that 2006 will be a strong year for Osmetech.

Our Critical Care Division is on track to achieve another profitable performance
and will continue to provide a strong base and proven infrastructure for the
Group overall as we introduce products in the molecular diagnostics market.

We fully expect to be able to demonstrate the value of our strong position and
the considerable opportunities that exist in the exciting molecular diagnostics
market as we enter the important commercialisation phase.

Ends

For further information:

Osmetech plc +44 (0)207 849 6027
James White, Chief Executive Officer
David Sandilands, Chief Financial Officer

madano partnership +44 (0)207 593 4000

Matthew Moth

Mark Way

The installation of instruments will provide the basis of future revenues by
introducing a wider range of tests, developed both by Osmetech and third
parties. In addition, our instruments have significant potential in other
markets, such as veterinary, environmental and forensics, which we would look to
exploit through strategic partnerships.

We fully expect to be able to demonstrate the value of our strong position and
the considerable opportunities that exist in the exciting molecular diagnostics
market as we enter the important commercialisation phase.

Another large holder has shown their hand. 3%+ holders and directors now control c63% of the issued shares of the company.

Osmetech PLC
05 May 2006

Osmetech plc ('Osmetech' or 'the Company')



The Company has been notified that following the acquisition of 1,100,000
ordinary shares, Universities Superannuation Scheme Limited now has an interest
in 4,780,000 Osmetech shares. The shares are registered under Chase Nominees Ltd
(USS).

The total holding represents approximately 3.627 per cent of the Company's
issued ordinary share capital.

The latest freebie from MW, which im sure he wont mind me posting here.

Catching the Cash

There has been nothing but good news from Osmetech (OMH) this year, yet the shares are languishing at 22.5p to 23.5p, way down from the 33.5p they touched in January. Though I hate to argue with the market, that fall looks foolish.

The price has not been helped by the clumsy surprise (certainly to the company) sale of 21m shares at 20p as Motorola simply chucked stock onto the market to clear the books (see my archives Money Down The Drain January 26). Nor has it been helped by the warning repeated with the March 21 figures that further funding would be required later this year to finance the launch of new products.

The share dump will not happen again. Motorola was simply recovering a little cash after effectively giving Clinical Micro Sensors (CMS) away in another of the shrewd cut-price purchases engineered by Osmo chief executive James White. The sale was executed, some say badly, by former broker Evolution. ABN Amro is now in place as a bright new broker with US connections (Osmos business is now firmly in the US).

The funding? This is intriguing. There have been some shrewd posts on the ADVFN bulletin board. These reason that the companys major institutional shareholders would not want more shares issued at current prices, effectively them, and might be keen to support a placing, perhaps at more than the current level.

Gartmore has over 18% of Osmo, and Schroders more than 14%. It seems that they are heavily committed to the story, and there is speculation that they might, indeed, be ready to support the business at a premium. There is also the possibility that Osmo could raise cash by selling some of the intellectual property which came in with CMS last summer. Remember, Motorola effectively acquired it for $280m in 2000, then spent $100m on research and development. Such a business ought to have stacks of value tucked away.

And if it cannot sell something, maybe Osmo could generate some cash by bringing in a partner somewhere.

All of this is sheer speculation, of course, but it does reinforce the notion that the Osmo management is acutely aware of the share price and reluctant to countenance further dilution, if at all possible.

When will money be raised? It is not clear. Will it be raised at this price? Probably not. Maybe the new broker can help here. An updated research report would help.

Bears and short sellers please note we are not dealing here with a company which makes money. It reported pre-tax losses of 5.4m for the eight months to December 31, and is forecast to lose around 10m for 2006. So there is ample room for non-believers to bash away, and it will take until 2008 before decent profits emerge.

That does not mean there is not significant value in the company as it stands. Take the critical care division, the bit built around the OPTI blood gas analysis business. That makes machines, and sells consumables for those machines. It is growing fast, with sales of 5.58m (up 78%) in the eight months to December 31. They are probably running close to 10m in the current year. Comparable businesses in the US have sold for between 2.8 and five times revenues. So the critical care division, which would be profitable if it could be stripped out of Osmo, is worth the current whole company market capitalisation of 30m on its own.

Critical care is going great guns, selling more machines which lead to more consumables sales. It sold perhaps 1,000 machines into the veterinary market last year, thanks to a link with veterinary distribution giant IDEXX, and could sell more this year. Each veterinary machine probably uses three consumables a day, against one a day in hospitals.

The human business specialises in near-patient testing (testing in the hospital or clinic, instead of taking samples to be not sent away for processing) and there are two new product launches set to help deliver growth this year the OPTI R multi-use consumable for higher usage customers, and OPTI LION, a low cost electrolyte only instrument. So OPTI looks good and growing.

The real excitement, however, lies with the molecular diagnostics division, for which there is nothing in the share price if you accept OPTI is worth 30m. This bears the research and development costs (there are 50 or 60 people working on the new P450 test alone), but has taken Osmo into an exciting and fast-growing niche market which could be very valuable.

Again, the bears could suggest that since Osmo picked up the businesses which largely comprise this vision for practically nothing, they are worth nothing. But they have had maybe half a billion dollars of research and development pumped into them and since Osmo bought in, have succeeded in getting FDA approval for products.

In January, Osmo won FDA approval for a test to detect cystic fibrosis, and for the e-Sensor DNA Detection machine which runs that test. The test produced results which achieved remarkable success. There are around one million tests for cystic fibrosis in the US each year, mostly carried out by qualified technicians on $100,000 machines in large central laboratories to which the samples are sent. They are charged at perhaps $400 or more a time.

The Osmo e-Sensor will go to hospitals which will be able to test in-house. Machines will start being installed in the first half of this year. Perhaps ten or twelve will be placed in 2006 running tests, with revenues generated by the consumables.

But the e-Sensor will not be confined to the cystic fibrosis tests, which are likely to be given to all childbearing couples. It can accommodate a variety of relatively complex molecular tests, analysing multiple genetic information, able to detect many different targets at once. There is intellectual property protected by over 70 international patents.

The next e-Sensor test for which Osmo is seeking FDA approval will be the Cytochrome P450 (CYP 450) pharmacogenomics assay. This should yield valuable information on drug metabolism, basically determining how individuals will react to different drugs, thus helping determine safety and dosage. That opens the way to personalised drugs a major advance.

Roche has such a test which sells at $800 a time. Hopefully, the Osmo version will win FDA approval next year. It should handle three major separate tests, with the first directed at Warfarin, which treats blood clotting, and is used by perhaps 20m people each year. Thousands suffer an adverse reaction each year.

Alongside producing these specific consumables for the e-Sensor, Osmo is talking to pharma companies who wish to run their tests on the machine. Others have the assays, but lack a suitable instrument.

In addition, Osmo expects in June to launch the OPTI GENE system, a machine for detecting DNA and RNA targets with simple assays. This uses technology developed by an earlier acquisition company, Molecular Sensing. It should provide results within 30 to 45 minutes using a single patient disposable cartridge. Once again, it is designed for near-patient testing in medium to smaller hospitals. The initial launch will take in thrombophilia assays.

In May, the company should also launch the OPTI TUBE. These are specially designed plastic tubes to replace the glass tubes now used by pharma giant Roche. There are some 50m glass tubes sold each year. The OPTI alternative costs a fraction of the Roche price, and is much safer. Roche has been granted a non-exclusive licence to make and sell it.

There is, then, a raft of new products about to come onstream. They range from the low-tech, low-cost but high volume items like OPTI TUBE to highly sophisticated machines and assays. These are all, arguably, in the share price for nothing.

If they take off, they could be worth a multiple of the current share price. But it will take a year or two for them to win a decent market share, and they will require financing along the way.

Tiny Osmo bought these much bigger opportunities for a song. Raising the full working capital required to get them to market would have been quite a stretch at the time. Now they are reaching the market, raising extra cash for the final push looks less daunting.

Clearly there are risks. There is an exciting list of new products with great potential, but they are not yet selling. They have not penetrated the market. The machines might well be given away so that Osmo can establish them in place, and then earn from high margin consumables.

Such a business might appear too complex and foreign to many UK investors. The research and development is taking place in the US, the main initial market, though there are links in the UK and Europe.

Clearly Osmo has some UK believers ready to back the business to take it to the next stage. New broker ABN Amro might be better able than Evolution to exploit market interest in America, where such companies are better understood.

As the products start to penetrate the market, and as worries about future funding are eliminated, the shares could advance sharply. But, once again, they are not without risk.

http://news.ft.com/cms/s/5d32d9d6-e643-11da-a36e-0000779e2340.html
Osmetech, the healthcare diagnostics group, firmed up 1.1 per cent to 22p after house broker ABN Amro initiated coverage with a buy recommendation and a 30p target price. The broker believes strong newsflow over the next 12 months will help highlight the value of Osmetechs molecular diagnostic assets.

http://www.timesonline.co.uk/article/0,,2095-2168219,00.html

USS increased their position

Osmetech PLC
26 May 2006

Osmetech plc ('Osmetech' or 'the Company')

The Company has been notified that following the acquisition of 720,000 ordinary
shares, Universities Superannuation Scheme Limited now has an interest in
5,500,000 Osmetech ordinary shares. The shares are registered under Chase
Nominees Ltd (USS).

The total holding represents approximately 4.17 per cent of the Company's issued
ordinary share capital.

MajorShareHolders No. Shares(%) Gartmore 22,016,240(16.70) Schroder 18,874,284 (14.32) UBS AG 7,700,000(5.84) Universities S S LTD 5,500,000(4.17) Pershing Keen 5,870,773 (4.45) Roche 2,444,688 (1.8) Total 62,405,985(47.28)

Looks as if the three blind mice have in fact got perfect eyesight.

Share price down to a lowly 18.5p after news of yet another fund raising exercise - diluting existing shareholdings and raising the number of shares in issue by over 50%.

Yuk.

well the rampers have shown they lack any sort of judgement. RAMP RAMP here and on competitors site. If anyone dared to question their so called wisdom they were banned from posting. This episode shows what idiots they are. I continue to hold.

Back to 30p+ very soon...IMHO.

MajorShareHolders No. Shares(%) Gartmore 22,016,240(16.70) Schroder 18,874,284 (14.32) UBS AG 7,700,000(5.84) Universities S S LTD 8,900,000(6.75) Pershing Keen 5,870,773 (4.45) Roche 2,444,688 (1.8) Total 65,805,985(49.86)

Can you keep that table up to date please!