After years of promise, PRM seems to be on the verge of a breakthrough into the big league. Deals have been signed in the last six months which will commercialise their stroke and bse tests into markets worth hundreds of million pounds and Sensitizer, their protein profiling toolkit, is tipped to be snapped up for big money royalties. Their 30% of Intronn Inc could be pure gold and their 60%+ of Veri-q has been described as a potential cash cow. And that's just for starters.

PRM - the wait continues .... and continues ..... ;o)

People were sucked in to buy at a higher price,but now it has fallen by considerable amount,is this time to buy or hold,some one on iii said there was an article in the paper about a possible take over,if true is this the time to buy .
as always dyor

There is always a possibility, but without customers willing to pay for all this Marker patent stuff....what value does PRM have? It may be that management sees value (for themselves) , but I suspect that if they turned to a MBO then after this long shareholders would ahve a case agaiinst the Chiefs' tardy performance towards shareholders who have suffered for far too long.
This company can keep its secrets, but just let the owners have a little dosh on the way, eh?

It wouldn't surprise me that something is about to happen, but I'd be surprised if those that don't know will benefit. Those that "know something" had better hold-back else they'll be insiders......and it's about time this company produced a decent set of results, deals with several - not all-or-nothing, with one big user.

Whoah!
Have just received the (PRM) Interim Report and it does explain what's going on in a considered way - Note that the Official Posting here ( Co. News) appears on my screen to be shifted to the right, and rather difficult to read.

Notwithstanding that this report is probably 100% accurate, it mentions the loan, it mentions the German Executive and also considers that vexing question - has another technology overtaken them?

Nevertheless, it does seem that "still" we do not have a position where the co is profitable....the loan helps credibility and other Execs are deferring salary (good thing too), so presumably there is sufficient belief in the products that Significant deals will be arriving "soon".

This has been a disapointing investment, characterised by a tendency to fall. Anyone in Nominee, should ask for a printed copy of this A5 publication.

I guess ADVFN is the place to be on this one. Seems to be some excitement brewing for the not to distant future. Are they finally going to announce some good news for their more than patient shareholders. Hopefully news this month.
Not to much further for me to go before break even but it would take some major news for all the long suffering 1 and worse 2 holders. Hindsight is a wonderful thing but a small percentage short on this along time ago while going long would have paid dividends by now. I'm going to have to look more closely at the world of shorting. I don't really agree with it but looking at my recent portfolio I would have made some good money !
Fingers crossed for everyone for good newes and license deals with some or even a big name player.
Obe

I don't short either, I think it has to be something you do when you see a no-brainer (like dot-coms before the fall), but the snag is that Spread-Bettiing co's are always advertising how easy it is to make money - this I doubt since it is THEY who make the money and that will cost you. I understand your position can be affected by"Spikes" which come and go like thieves in the night - you might think the sp has moved 2p today, but the sp company will have stopped you out 20p above. When you come to collect, they will say "but you were stopped out sir, such a pity" - frankly I do not believe folk make money by short-selling unless they are "experienced operators" Therefore best left to the likes of EK.
Lastly, why risk money shorting, when you can sell your own stock? If you think it will go down, be brave and take the risk....you can buy them back and there are no spikes to get you.
After the dot-com I sold my major losses (How Painful!) and then 2years later bought them back at significantly lower prices ...in theory I had lost, but in reality I was "in" at a more-realistic price with a wad of Losses to cover early gainers. None has come good yet, but my av. price is getting ever-so close.
I have a most-recent PRM purchase in an ISA at about 57p - so in all I average about 80p - - - will it double? That would be brave to predict, for this co has been very good at disapointing; - why change a formula that seems to work?

Hi hangon.
I'm in at 68p and have been for some time now but nothing compared to long time holders. I missed the recent spike at just around break even but even then I would have no doubt found I couldn't sell them all in one go or the system was down. I find with the likes of Halifax on-line dealing that the system doesn't generally let you do what you want when you want especially when the sp is moving or fluctuating quickly. I know it's not all down to them but I am suspicous of the whole set-up.
I too would like to see double and it's possible from what I have read but the days of believing much of what is said or predicted has long since vanished. Hoping for a profit or break even shortly though with the recent excitement and expectation. Good luck at your higher average, sneaking closer though !
Obe

Here we are in 2007 and still waiting for the good news, Ch.Exec's loan is almost all spent, so I hear and there is another round of loan but curiously this time supported by the IP - so it is possible there could be a debt-for-equity swap...ie buy the Co. on the cheap, from under the noses of the long-term shareholders.....tut tut, that was never their intention - was it?
However, 2-years ago we were assured that a Deal was just round the corner and that the whole World was excited by PRM's IP - well, I don't see it and suspect when the blindfold comes off the execs, they will be forced to recognise no-one want their stuff - the technology has moved-on at a slow pace....but a lot faster than PRM's Execs who have been faffing about (can I say that?), far too long.
Do they fear asking their customers for money? Oh! I forgot...they still don't have any customers, only shareholders.
Cull the Lot and get some commercial-types in; strip out all the hangers-on and let's see what's left...if PRM has any value, then let's exploit it. Otherwise let someone else keep you - mowing the grass at a golf club should be a worthy task, not too far from their capabilities....pleasant enough for 6 months each year.

So with debt mounting and no sales what is this sp telling us? - - - anyone?

Well, 'exon' (if you're still around), then if PRM was "On the verge of something big?" on 28 May 2003 - then looks after todays AGM that it's almost there?

todays news release is entitled 'Allowance of US Patent on Isobaric Tandem Mass Tags (TMT) Allowance of European Patent (TMT2)'

So, even if it's not the 'last piece' in the jigsaw, it's the one that ensures all the pieces are on the table ready for fitting....

You may be right, but funny thing is they've been telling us about their IP for years and I'm getting tired of it.......it's one thing to have great protection (provided you have the finances to back it up, if a challenger pops up)....and quite another thing to get someone to pay good money to use it.
It may be very clever, it may be ever-so well protected, but if it has no use ( -or- that's the perception.), ...then no-one will buy from you.
[[ - it's a bit like having a new-fanged fruit...say, a cross between apples and pears - First find out if the Public has a taste for it - or does it make a good drink etc. only then is it worth funding further research into other ugly fruits..]]

No, I suspect this is the same posturing of PRM-( that we have witnessed for years) - if it was coming good, the City would be buying like there was a gold-rush.
sp down again today, hence my comments.....oh dear, and I had high hopes at over 1....

'hangon'.... agreed it's failed to live up to previous promises .... but it might finally be coming together ...... patents allowed ...... and now today news of Intronn tie-up...

I assume most city folk would only consider buying once more of the pieces are in place given the risk / reward ratio (with their City jobs).....

time will tell....

The shares went up today from 1pm for no obvious (i.e. published) reason. They closed at 41.25-41.50 which was 9.21% up on the day.

It's possible they are about to announce their first commercial contract for their tandem mass tags - otherwise why the rise?

I've lost money on this one before - as you say: lots of promises - but perhaps they are finally moving forward??

well, a nice spurt up this afternoon from PRM..... will await next week with interest.....another piece of 'jigsaw' finally coming.... ?

I wasn't around today to keep an eye on this, so I missed it. But clearly something must be up for the sp to keep heading upwards.

In the RNS of 30 July they mentioned that: "The latest patent
grants should now enable us to complete commercialisation of TMT through
outlicensing and to generate strong revenue through licence income, product
sales and royalties."

Guess they're finally getting there.

From what I've seen on another site, then final published confirmation is due to be posted from US Patent Office in just over a couple of weeks time. Timescale of final publication is governed by the pre-set Patent Office procedures / timelines. Guess if gains in PRM SP rise continue then they'll be helped along by some closing their 'shorts' on it. Let's see if Evil K gets burned...... (Hope so). The next few months might decide it one way or t'other.

"The next few months", we will see news in the next couple of weeks.

Well, even got a mention in the Telegraph today....

http://www.telegraph.co.uk/news/main.jhtml?xml=/news/2007/10/28/nblood128.xml

Another piece in the jigsaw....

13/11/2007 @ 18:15
Proteome Sciences granted US patent for isobaric tandem mass tags

LONDON (Thomson Financial) - Proteome Sciences PLC said it has been granted
a US patent for its isobaric tandem mass tags, reagents used in protein
experiments.
The company, which makes machines that detect proteins in diseases, said the
patent contains broad claims to sets of isobaric mass tags.
The patent issuance will enable Proteome Sciences to complete
commercialisation and outlicensing of isobaric tandem mass tags and to generate
strong revenue through licence income, product sales and royalties.
TFN.newsdesk@thomson.com

Without seeming to be rude
(oh well here goes:-)

- Does anyone care anymore.?

I could exist easily not hearing another word from PRM's management - that is until they send me a nice dividend.

It's an easy process...
1) You have a hunch of an invention and patent it
2) find someone to finance it
3) make some
4) you sell 'em
5) make some more, using the profit ( from 3/4 )
6) repeat 3,4,5 and return some of the initial finance to investors
7) end of year accounts show "surplus" - send investors a dividend.

Crikey, it really is easy - and each two-steps should only take 1-year ( as some may be done in paprallel). . .

. yet what do we get from PRM ..?

Endless delays and promises of "round the corner" -variety.
By the time they get round to it, the dollar will be even lower . . . it doesn't look good, does it?
(I'll stop now)