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Allied Mind - Science & Technology development (ALM)     

HARRYCAT - 23 Jul 2014 12:01

Chart.aspx?Provider=EODIntra&Code=ALM&Sihttp://www.alliedminds.com/

"Allied Minds is an innovation company that forms, funds, manages and builds startups based on early-stage technology originating from U.S. universities and federally funded research institutions. We created a new business model for overcoming early-stage development gap between basic research and commercial development. Our investors are aligned with our vision that cutting-edge invention is an attractive, yet under-developed, asset class. We review numerous ideas but only select opportunities with potential to deliver outsized returns. We create subsidiaries led by seasoned management who know how to turn academic breakthroughs into commercial products and then take them to market. We provide our subsidiaries with capital resources, from seed to self-sustainment. Our aim is to promote growth, generate jobs, foster innovation and create societal benefit."

HARRYCAT - 23 Jul 2014 12:03 - 2 of 64

StockMarketWire.com
Allied Minds has confirmed that its entire issued ordinary share capital of 209,499,425 ordinary shares has started trading on the London Stock Exchange's main market under the ticker 'ALM', 25th June 2014. Flotation price 190p.

HARRYCAT - 04 Aug 2014 07:51 - 3 of 64

(BOSTON and NEW YORK - Aug 4, 2014)
- Allied Minds (LSE: ALM) and Bristol-Myers Squibb Company (NYSE: BMY) today announced the formation of Allied-Bristol Life Sciences LLC, a new jointly owned enterprise created to identify and foster research and pre-clinical development of biopharmaceutical innovations from leading university research institutions across the U.S.
Allied-Bristol Life Sciences LLC will focus on efficiently and effectively converting discoveries from university research institutions into therapeutic candidates for clinical development, and ultimately approved therapies that address serious diseases. For programs identified by the new enterprise, university researchers will be able to access Bristol-Myers Squibb's drug discovery research expertise, and Allied Minds' financial and management experience.
"The innovations developed in U.S. research institutions represent an important resource for scientific advancement, as well as economic development and financial returns," said Chris Silva, Chief Executive Officer of Allied Minds. "Our partnership with Bristol-Myers Squibb combines complementary strengths, resources, reach and expertise to create an exciting new paradigm in the drug development space."
Allied-Bristol Life Sciences LLC brings together cutting-edge ideas, BioPharma experience and drug discovery expertise focused on maximizing the potential of new scientific approaches to addressing serious disease," said Carl Decicco, senior vice president and Head of Discovery, Bristol-Myers Squibb. "We believe this new venture will enhance the translation of early-stage academic research and will ultimately help advance important potential new medicines more efficiently."

HARRYCAT - 27 Aug 2014 07:54 - 4 of 64

Allied Minds Announces the Formation of Whitewood Encryption Systems, Inc.

· Whitewood aims to develop next-generation systems of data encryption that leverage advanced cryptography technologies originating from U.S. research centers.
· Whitewood was founded upon technologies created at Los Alamos National Laboratory, and its initial products are expected to include a quantum random number generator and a system of quantum key management.


Boston (August 27, 2014) - Allied Minds (LSE: ALM), an innovative U.S. science and technology development and commercialization company, announced today the formation of Whitewood Encryption Systems, Inc., a builder of next-generation systems of data encryption that leverage advanced cryptography technologies emerging from U.S. centers of research excellence. Additionally, the company announced today it has exclusively licensed intellectual property from Los Alamos National Laboratory for quantum cryptography.

Whitewood seeks to meet the growing demand for cryptography products that can protect consumers and businesses from a rapidly escalating number of malicious, costly - and increasingly sophisticated - security attacks and data leakages. Whitewood's advanced cryptography systems will provide defenders with enhanced security through scalable, cost-effective solutions that meet high-speed requirements for the efficient transfer of data.

The company's initial products, anticipated to be a high-entropy, high-throughput quantum random number generator and a next-generation, scalable system of quantum key management, will be founded upon technologies created at Los Alamos National Laboratory. These technologies, backed by nearly two decades of research, are expected to offer unprecedented levels of speed and security for data encryption by providing a quantum physics-based alternative to traditional cryptographic practices.

HARRYCAT - 28 Aug 2014 08:40 - 5 of 64

Allied Minds Announces Half-Yearly Results

http://www.moneyam.com/action/news/showArticle?id=4875343

HY14 Financial Highlights

· Net cash and cash equivalents at 30 June 2014: $228.5m (FY13:$104.6m)

· Revenue: $2.9m (HY13: $0.7m)

· Net loss: $27.2m (HY13: $17.6m), of which $21.9m attributable to Allied Minds (HY13: $13.6m)

"The successful completion of the IPO marks the beginning of an exciting new phase of growth and opportunity for Allied Minds and our diversified portfolio of 20 businesses. We are pleased with the positive response that we received from investors to the IPO, and look forward to enhancing and accelerating our efforts to commercialise the innovative science and technologies from our extensive network of partners at U.S. universities and government research institutions."

HARRYCAT - 01 Sep 2014 10:30 - 6 of 64

One of the few IPO's which has done well since float recently. Up another 6% today.

HARRYCAT - 05 Sep 2014 09:41 - 7 of 64

Not far from the £3 mark. I think 320p was the last broker target I saw.

skinny - 05 Sep 2014 09:49 - 8 of 64

Nice find Harry - I wish I'd found the thread in July!

Last/only broker :- 08 Aug 14 Jefferies International Buy 298.50 - 320.00 Initiates/Starts

HARRYCAT - 07 Oct 2014 08:00 - 9 of 64

StockMarketWire.com
Allied Minds, an innovative US science and technology development and commercialisation company, has announced the launch of Novare Pharmaceuticals.

Novare is a biotechnology company focused on developing therapeutic products that help the body replenish and rebuild itself using its own tissue through the modulation of RHAMM. Modulation of RHAMM is also of benefit in inflammatory diseases such as Bronchopulmonary Dysplasia (BPD).

Novare is an expansion of the Allied Minds subsidiary previously called ProGDerm, which is developing a dermal filler for aesthetic applications that works via the modulation of the Receptor for Hyaluronan Mediated Motility, or RHAMM.

This research is being led by Dr. Eva Turley, an oncology scientist at the London Health Sciences Centre (LHSC) in London, Ontario, in collaboration with MJ Bissell, a world-renowned cell biologist at Lawrence Berkeley National Laboratories in Berkeley, California.

Turley and colleagues have now uncovered the potential for additional applications of RHAMM modulation that may help solve some of today's biggest medical challenges, including arthritis, fibrotic diseases such as Bronchopulmonary Dysplasia (BPD) in premature infants and Idiopathic Pulmonary Fibrosis (IPF), and the reduction and possible elimination of keloid scars.

This breakthrough in tissue engineering may also provide an opportunity to regenerate and reconstruct women's breasts after a mastectomy through the localized stimulation of the body's own adipocyte (fat) stem cells. Novare has licensed from LHSC additional RHAMM compounds discovered by Dr. Turley, who is also serving as Novare's Chief Scientist, and Dr. Leonard Luyt, a peptide chemist at LHSC, allowing the company to more than double its library of RHAMM-binding peptides - and increase potential applications. Novare chief executive Michael Delmage said: "We are excited by the opportunity to further explore the potential therapeutic applications of RHAMM modulation technologies as the studies conducted to date show promising, medically relevant, drug-induced biological responses."

HARRYCAT - 09 Oct 2014 08:09 - 10 of 64

StockMarketWire.com
Allied Minds subsidiary Spin Transfer Technologies has raised $70m to accelerate commercialisation of its innovative computer memory technology. STT's patented OST-MRAM technology is a disruptive innovation in the field of spin-transfer-based MRAM devices by enabling faster switching speeds, lower power operation, reduced manufactured device cost and scalability to smaller lithographic dimensions.

OST-MRAM's application areas can potentially address large parts of the semiconductor market - in particular, the standalone memory markets and the embedded memory market in logic, microprocessors/microcontrollers and analog integrated circuits.

Woodford Investment Management (WIM) led this round of financing, demonstrating its continued support for the commercialization model of academic research pioneered in the U.S. by Allied Minds. In addition, Invesco Asset Management (Invesco) increased its stake and maintains its position as the largest institutional investor in the Fremont, California-based company. SandAire, a private wealth investment fund in London, joined the investor group with its participation in the financing.

HARRYCAT - 30 Oct 2014 08:23 - 11 of 64

StockMarketWire.com
Allied Minds is entering into an exclusive, worldwide licensing agreement with Columbia University that has led to the formation of a new subsidiary, Seamless Devices, Inc.

Seamless Devices is developing applications for a novel technique in analog signal processing that will make it possible to produce high-performance signals even as transistors are scaled down in size deep into the nanoscale.

The technology, developed in the laboratory of Columbia University Electrical Engineering Professor Peter Kinget, serves a wide range of applications across several industries, including consumer electronics, telecommunications hardware, instrumentation, network hardware, healthcare devices, transportation and military systems.

HARRYCAT - 12 Nov 2014 10:47 - 12 of 64

Appointment of Joint Broker
Allied Minds plc (LSE: ALM), an innovative U.S. science and technology development and commercialisation company, is pleased to announce that it has appointed Numis Securities Limited as joint Corporate Broker to the Company, alongside Jefferies Hoare Govett, with immediate effect.

HARRYCAT - 04 Dec 2014 07:40 - 13 of 64

SciFluor Life Sciences Awarded U.S. Patent for Integrin αvβ3 Inhibitors Designed for the Topical Treatment of Retinal Disease
· Patent-protected topical integrin antagonist could potentially revolutionize retinal disease therapy.

· Addressable markets include wet Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME).

· Issuance of first patent validates SciFluor's innovative approach to small molecule drug discovery by the strategic incorporation of fluorine.


Cambridge, Mass. (Dec. 4, 2014) - SciFluor Life Sciences, LLC, an emerging clinical stage biopharmaceutical company that creates innovative therapeutics for patients with ophthalmologic and neurologic disease, announced today that the U.S. Patent and Trademark Office (USPTO) has issued U.S. Patent No. 8,901,144 with claims covering the novel compound SF0166. SciFluor's SF0166 is a small molecule integrin antagonist designed to treat retinal disease, including Age-related Macular Degeneration (AMD) and Diabetic Macular Edema (DME), via topical administration to the eye.

Topical administration of medications (eye drops) for treating the retina in order to eliminate the need to inject compounds to the back of the eye has been considered an enormous challenge until now. Current treatments require repeated injections into the back of the eye in order to get enough of the drug where it is needed. A drug that could localize in the back of the eye after administration as an eye drop would remove the need for repeated injections. To date, no topically administered drug has been approved for these indications.

Ben Askew, PhD, Vice President of Research, said, "The issuance of the patent covering SF0166 provides validation of our fluorine-centered approach to rapidly bringing new transformational therapies to patients with serious illnesses. SF0166 demonstrates how the appropriate fluorine-containing modifications can improve the physical properties of a molecule to address the challenge of getting enough drug to the back of the eye without injections."

Dr. Askew is the lead on the SF0166 therapeutic program, which is targeted to treat both wet Age-related Macular Degeneration (AMD) as well as Diabetic Macular Edema (DME).

"The scientific depth of this team and the team's ability to rapidly evolve this candidate and to obtain an issued patent protecting this lead compound in such an enormous field of retinal disease is highly impressive. We are excited to advance this program. This is the first of many opportunities at SciFluor that we are pursuing to strategically capitalize on the transformational power of fluorine," said Omar Amirana, MD, SciFluor's Chief Executive Officer and Senior Vice President at Allied Minds.

SciFluor is a subsidiary of Allied Minds (LSE: ALM), an innovative U.S. science and technology development and commercialization company.

HARRYCAT - 09 Dec 2014 11:29 - 14 of 64

330p. Pushing into new territory!

HARRYCAT - 08 Jan 2015 09:11 - 15 of 64

StockMarketWire.com
Allied Minds subsidiary SciFluor Life Sciences has been awarded a US patent covering the novel compound SF0034, a potent and selective neuronal potassium channel activator, designed to be a significantly improved version of the first-in-class KCNQ2/3 activator drug, ezogabine (POTIGA).

POTIGA was approved in 2011 for treatment of partial-onset epilepsy in adults, but its clinical use was severely restricted in 2013 due to latent toxicities which are not thought to be associated with its mechanism of action.

HARRYCAT - 13 Jan 2015 11:48 - 16 of 64

Numis note today:
"US universities and federal research laboratories spend over $170bn pa on research, and Allied Minds has built a network of over 60 such organisations from which it identifies novel IP and technologies. It forms companies around this IP, providing funding, management and legal and back office support for c.80-100% of the equity. Allied Minds has formed 21 subsidiaries to-date, with its holdings valued around $411m and with another c.$175m cash able to be deployed. The company has almost $250m of capital to invest in its existing portfolio and to develop new companies, so we believe that it is well capitalised to continue to build value. We value Allied Minds at 455p/share, implying 2.5x based on an assumption of 10-year IRR of 26% (compared to c.60% historical IRR), and initiate research coverage with a Buy rating.
The largest two holdings are:
Spin Transfer Technologies (STT) has developed a next-generation memory technology, which potentially has speed, reliability, energy consumption and cost benefits over incumbent technologies – we estimate that the addressable market is over $70bn. The company has already made significant technical progress and has recently been funded for the next phase of development, which should result in prototype products shipping in late CY15. It is most likely that an IP business model will be used, where STT licenses the technology to existing players in the memory market and earns royalties on chip sales (similar to ARM). However, the company may be acquired by one of those players if momentum around its technology continues to build.
RF Biocidics (RFB). With one in six people per year suffering from food-borne illnesses, and increasing regulatory emphasis on prevention, we believe that food disinfection will remain a growing trend. Existing disinfection methods have significant drawbacks, so RF Biocidics has developed a new system that uses radiofrequency. This has been integrated into two products that have already been sold to some major food producers.
Forecasts. Allied Minds' control over its subsidiaries means it consolidates their accounts, thus showing investment as operating and investing cash outflows. We model STT and RFB together generating $60m of revenue by 2018, which helps to offset an investment rate we model at $50-60m pa. Key risks include unanticipated technical hurdles at STT and slower commercial adoption of RFB's products.

HARRYCAT - 22 Jan 2015 11:24 - 17 of 64

Now more than doubled since the float. Currently 435p mid .

HARRYCAT - 27 Feb 2015 10:40 - 18 of 64

Has now passed the Numis price target of 455p. Possibly getting a little ahead of itself now? Consolidation (pause for breath) would make me happy now!

jimmy b - 27 Feb 2015 10:42 - 19 of 64

Looks like you have been on your own here HARRY , good pick .

HARRYCAT - 02 Mar 2015 08:20 - 20 of 64

Thanks jimmy. Going like a train! Trouble is, I have no idea why! No news, yet sp now surged past the £6 level.

skinny - 02 Mar 2015 08:35 - 21 of 64

Yes - fancy keeping these to yourself Harry! :-)
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