Surprised no one is talking about the Bio stock. Neede a good announcement and it came at last. Up 14% at 100p

AFX
Compounds discovered that could enhance treatment by chemotherapy and radiotherapy

BioFocus PLC and Australian Cancer Technology Ltd said they have discovered novel lead compounds (Kinase-inhibitors) that have the potential to enhance the effectiveness of traditional chemotherapy and radiotherapy approaches to cancer treatment.BioFocus shares gained 25.7% to 110p.

A lead candidate drug will be developed for patent and commercialisation activities.



The two companies in joint venture said compounds have been discovered that are both potent and show efficacy against the key drug target, Chk1 Kinase.

BioFocus chief executive Geoff McMillan said: 'We are very pleased that high throughput screening of compounds from BioFocus' proprietary library has returned a number of confirmed 'hit' compounds, which selectively inhibit the key Chk1 Kinase enzyme. Such compounds would potentially enhance cancer cell death in conjunction with established treatment regimens'.

The partners are concentrating on maximising potency and demonstrating the effect of enhanced cancer cell death by constructing a series of compounds around the most potent (lead) compound. The partners expect to lodge patents for these novel compounds later in the year and commence commercialisation negotiations shortly thereafter.

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