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THE TALK TO YOURSELF THREAD. (NOWT)     

goldfinger - 09 Jun 2005 12:25

Thought Id start this one going because its rather dead on this board at the moment and I suppose all my usual muckers are either at the Stella tennis event watching Dim Tim (lose again) or at Henly Regatta eating cucumber sandwiches (they wish,...NOT).

Anyway please feel free to just talk to yourself blast away and let it go on any company or subject you wish. Just wish Id thought of this one before.

cheers GF.

VICTIM - 24 Dec 2017 14:19 - 79721 of 81564

But Ringo Starr who's lived a life outside these shores for some 40 years or so is going to get a sirdom , makes me sick .

Haystack - 24 Dec 2017 17:59 - 79722 of 81564

Good

ExecLine - 25 Dec 2017 13:08 - 79723 of 81564

Which?

1. Good, that Ringo Starr, who has live outside of the country for 40 years or so, is getting a knighthood?

or

2. Good, that 'VICTIM', along with thousands of others, including me, is made to feel sick about it?

I'd like to see Farage get a knighthood too.

The former UKIP leader has apparently been over-looked for a knighthood because he campaigned for Brexit. Meanwhile every one of the 'Remainers' got either a CBE or a knighthood.

Mind you, the honours system stinks, anyway.

cynic - 25 Dec 2017 15:35 - 79724 of 81564

why would farage warrant any honour let alone a knighthood?

Haystack - 25 Dec 2017 17:25 - 79725 of 81564

Farage not even an MP. Didn't lead the leave campaign.

Dil - 25 Dec 2017 18:51 - 79726 of 81564

Let's be fair cynic why do half of those knighted deserve it ?

Fred1new - 27 Dec 2017 10:30 - 79727 of 81564

Haystack - 27 Dec 2017 13:19 - 79728 of 81564

Honours are not really honours. They are patronage

iturama - 27 Dec 2017 14:36 - 79729 of 81564

You're right Hays. They are used for abusive political patronage and are no longer worthy of the term Honour since few of the politicos that receive them have any. Politicians and members of any political party should be banned from such awards (rewards?). I'd rather see a first responder recognised than the likes of Clegg; and he is not the worst. Imagine.

cynic - 27 Dec 2017 15:44 - 79730 of 81564

DIL - i don't disagree but that is no reason to add farage to their numbers

ExecLine - 29 Dec 2017 16:59 - 79731 of 81564

Overindulged?

Hmmm? Hope is at hand....

Tiny tummy patch could cut fat by one third in four weeks...without exercise



Prof Chen Peng (left) holding the drug-laden microneedle fat burning patch with Asst Prof Xu Chenjie CREDIT: NANYANG TECHNOLOGICAL UNIVERSITY

Telegraph. Sarah Knapton, science editor
29 DECEMBER 2017 • 2:53PM
For those who have overindulged during the Christmas period help may be at hand from scientists in Singapore.

A tiny tummy patch has been shown to cut body fat by 30 per cent in just 28 days without the need to exercise.

The patch is covered in hundreds of microneedles which are smaller than a human hair and gradually supply a dose of two weight-loss drugs.

The drug combination works to transform stubborn white fat into more manageable brown fat, which is burned away as energy by the body to keep warm.

Although the patch has so far only been tested in animals, scientists at the Nanyang Technological University (NTU) want to move to human trials quickly, and have already received interest from several biotech companies who are keen to develop the device.

It is estimated that two thirds of Britons - 36 million - will be overweight of obese by 2025 and weight gain is a risk factor for many health problems, including diabetes, heart disease, stroke and some cancers.

But scientists believe the patch, which costs around £2.50 to make, could help people who struggle to lose weight, without needing to resort to costly surgery.

“What we aim to develop is a painless patch that everyone could use easily, which is unobtrusive and yet affordable,” said Prof Chen Peng, a biotechnology and obesity expert at NTU.

“Most importantly, our solution aims to use a person’s own body fats to burn more energy, which is a natural process in babies.”

The patch delivers the diet drug ‘Beta-3 adrenergic receptor agonist’ and a thyroid hormone called ‘T3 triiodothyronine’ which is a commonly used for medication for an underactive thyroid gland.

When the patch is pressed into the skin for about two minutes, the micro-needles become embedded and the patch can then be removed.

As the needles degrade, the drug molecules slowly make their way to the energy-storing white fat underneath the skin layer, turning it into energy-burning brown fat.

Brown fats are found in babies and they help to keep the baby warm by burning energy. As humans grow older, the amount of brown fats lessens and is replaced with white fats, which are stored and are difficult to remove.

Experiments in mice, which were fed on a high-fat diet, showed that the patch reduced their fat mass by more than 30 percent over a period of just four weeks. It also significantly lowered their blood cholesterol and levels of fatty acid.

Two thirds of Britons will be overweight or obese by 2025, according to estimates
Two thirds of Britons will be overweight or obese by 2025, according to estimates CREDIT: CHRIS RADBURN PA
Assistant Professor Xu Chenjie of NTU, added: “With the embedded microneedles in the skin of the mice, the surrounding fats started browning in five days, which helped to increase the energy expenditure of the mice, leading to a reduction in body fat gain.

“The amount of drugs we used in the patch is much less than those used in oral medication or an injected dose. This lowers the drug ingredient costs while our slow-release design minimises its side effects.”

Obesity and diabetes combined already costs the UK more than £5 billion each year and is likely to rise to £50 billion by 2050 according to the World Obesity Federation.

Professor Melvin Leow, of NTU, added: “These data should encourage Phase I Clinical studies in humans to translate these basic science findings to the bedside, with the hope that these microneedle patches may be developed into an established cost-effective method for the prevention or treatment of obesity in the near future.”

The research was published in the journal Small Methods.

cynic - 29 Dec 2017 17:34 - 79732 of 81564

a good massage with snakeoil is invaluable .... medical science has proved it

Chris Carson - 29 Dec 2017 17:46 - 79733 of 81564

Aye getting off your fat arse and taking some exercise also works. (Not to put tooo fine a point on it) :o)

Dil - 29 Dec 2017 19:12 - 79734 of 81564

Could do with a truck load of those here in the valleys.

VICTIM - 30 Dec 2017 08:36 - 79735 of 81564

I honestly feel physically sick , Glegg somehow has received a Knighthood , good god is there nothing we can do , it's beyond anything .

VICTIM - 30 Dec 2017 08:40 - 79736 of 81564

Eamonn Holmes services to broadcasting , don't they realise these people get paid and waited on hand and foot . It's just sick .

hilary - 30 Dec 2017 09:02 - 79737 of 81564

Is there anything in life that you're happy with, Victim? Just curious.

VICTIM - 30 Dec 2017 09:04 - 79738 of 81564

A bit harsh there i think just my opinion you know , you must be easily pleased or just trying to be funny .

ExecLine - 30 Dec 2017 09:47 - 79739 of 81564

I just have to say how upset I am about Nick Clegg and Ringo Starr getting knighthoods.

Ringo spends his life living between California and Switzerland and, I would suspect, most likely doesn't even pay UK taxes. So a good example there? NOT.

Nick Clegg is famous for promising to slash student fees and then tripling them - and not much else. I can't even believe he is a Tory crony. He had previously declined any position in the Lords which he wanted to abolish. Maybe his knighthood makes up for him not going up to the H of L.

There are a few people out there who should have been given awards, IMHO. Most blatantly, people like Nigel Farage, who did an absolutely fantastic job explaining the negatives of the EU to us all. So much so, that he was probably the most influential person in creating the national Brexit vote. I just cannot believe how he has been snubbed by the higher Tory establishment. His comments about the awards system tell it just exactly how it is. I think it needs abolishing altogether if it produces the crap awards results like Ringo and Nick Clegg.

Roll on the time when Theresa May steps down and Jacob Rees-Mogg steps up.

hilary - 30 Dec 2017 09:48 - 79740 of 81564

Victim,

If I scroll through your recent posts, I see rants at Fred, complaints about the EU, moans about remoaners, moans about social media users, negative comments on Mickey Owen, and then some. And now you're unhappy because folks have received New Year honours who, apparently, haven't done anything of merit to deserve those honours.

I just figured it might be easier if you told us what it is in life that you are happy with, rather than leaving us all to guess at random.
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