RHPS has just mentioned the above in an e-mail, they have gone up 240% today - started at 0.60 and finished up at 1.65. Look to be quite interesting.

Sorry, did not know there was already a thread for this - but still interesting.

rhps - arrrrghhhhhhhhhhhhh noooooooooooooooo - get out of sar quick then - lol!!!

keep an eye on pyc perhaps tomorrow - if i remember correctly pyc & sar have what i would consider a close relationship - check out the directors and see who is on both boards if it hasnt changed from when i last looked a year or so ago - also left an old rns on the other thread - cheers

http://www.barchart.com/opinions/stocks/SAR.LS

lol

gonna take me more than this week off - yeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeehaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

gla

I tried to buy these at 2.60 but it wouldn't let me 40 mins ago and am waiting an executed trade so all they are doing is going up and up, good luck to you.

cheers 3 monkies

dont forget this goes up even further normally in the afternoon when the yanks login who knows where this will stop - 4.7p now 10p later??? kerchinnnggggggg

i am running free and massive profits so well chuffed

i hope you do well too and anyone else

The wonderful share dealing has just executed me deal and I had to pay 4.7774, great - I am sick of the Halifax - they don't mind one selling buy buying is a different matter - over 2p more than it was when I wanted to deal. Pooooooooo

It has a market cap of 42 mill.....what goes up must come down.good luck

That wasn't the answer I really needed - they have gone down and now the news isn't helping. Hope I don't have to wait years to get back to what I had to pay hahaha!!! Me and many millions of others by the look of it.

Pity the company didn't make their 'somewhat restrained' statement abit earlier, guess that would have saved quite a few people a fair bit, me included!!!!!!!!!!

Your so right, uuuggggggggggg!!!!!!!!! Sick of having bad luck. I have bought some pyc as well and they have gone down also, as the company doesn't know why the shares have sored. Got Paul Harper on both boards whethere that makes a difference I haven't a clue. Think I should return to a day job!

3 monkies - ohhh no dude - i hope you made some before that 4.7 buy you mentioned and was out of profit

sar have imo been a bit slippery with that rns - but basically doesnt change anything

i am hoping for you that the yanks have their surge this afternoon - i sold all my free shares not long after my last post when i noticed at just under 5 it was changing - gl

may dip in again if it drops enough for this afternoon - you might want to avg down to help your escape price??

Oh Gibby, what a mess. I hope the Yanks have a surge to, don't know if there are any funds to avg. down will have to see what this afternoon brings. A wonderful thing if it ever gets a license and how it could help thousands/millions of people.

Good luck. It was my first time buy so no profits but in the red!!!! Ough.

I, after 5 yrs of dealing actually listened to myself, thought at 2.5p that was too much to buy in, so watched and spat teeth when it went to 5p. BUT I'm still here to play another day, could have made good profit but not quick enough. Have held pyc at 6 for some time and will hold, wait and see. know the feeling well 3 monkeys.,.

Dot.com Dvu!

My WONDERFUL HALIFAX SHARE DEALING WENT PEAR SHAPED ON ME, I tried and tried since 8.00 a.m. and then did an executed trade which I have never ever done before so by the time they shifted their bums restult being as above. Will never do another one either.

3 monkies
I also feel your pain what a sh***t I have been watching on the side line as gibby says this could go back up later today and properly will.

Live in hope!!!!! A hell of a lot of trades (making the stock brokers rich if nothing else)!!

on a scale of 1-10 whats the likely hood of making a bit of dosh this pm then, american market open in about an hour, can buy at 3.40p at mo.??

The question is how much is the company worth?

If I have them then the chances of making money is zilch haha!! No idea what the company is worth, not in the know - just bought them -what a silly billy I am.

A punter on the other side said 7p by Fri thats a 90+m M/Cap, you cannot put a price on the M/Cap at the moment this is being driven by traders when they have gone this is going down. It can take up to ten years to bring a drug to the market take a look at ASM and even then it could fall at the last hurdle.

Thanks chaps, think I'll sit on my hands...

The chances of these going back up today or whenever is looking very remote - hope all you luck ones can take a month off!!!!!

and down she goes......ground floor mr peacock.,.

Correct Oh! Dam! wish I had sat on my hands instead of my butt. Yanks are not biting!!! Wouldn't mind if they go to what I paid by Friday and out I would be. Silly bitch that I am.

:0) bitch.......never.......bit with a ch yes!!

Oh! Yesssssssss! A skint one at that if I carry on doing stupid things!

Hi Balerboy

You said you have held PYC for sometime now at 6, may I ask is that 0.06 or 0.60?

Cheers

lol, 0.006 was in profit this am (0.013), but had to take dog to vets and bl**dy missed it.

You must be nicely in Profit anyway as I bought in at 0.5658 or have I got it wrong? Perhaps we should go to the vets and leave the dogs to do the shares, we might be better off!!!!!! I think the budgie could do better than me at the mo.

Sorry I've put decimal point wrong on spread sheet. .58p

Gets confusing when mam uses all pence quote and and pence in spread sheet if you know what i mean........on spread sheet it is 0.0058 of a penny...

Oh shrit!! Similar to myself then - was hoping it was good for you. At least you refrained from buying SAR. Hope dog is okay.

Ha, yeh she's fine now.....has a liking for the cat litter tray and gave herself the Sh*ts lol.

Balerboy please could you tell me why people have to be so sarcastic on this Investors Room - I have never joined in until recently as I did not like the sarcasm. At the end of the day we are all only trying to do out best for ourselves, (dogs, cats, budgies included) - I am at the wrong side of life to be sarcatic (watch this space haha!!) Think it would be nice if everyone could be helpful, advise geriatrics ha! and be in the human race. May I add I haven't got a spread sheet (hope that makes you laugh), I just have a very untidy filing system - that says a lot about me don't you think? Oh! good luck tomorrow in what ever you do and keep the dog away from the cat littler or bring me the cat to dispose of the budgie - my dog is not doing a very good job hehehehe!!!!!!!!!

I'm as green as they come when it comes to share dealing but after 5 yrs am making modest profits but still making stupid mistakes....(Asos). No one to blame but myself!!
I can't work out the fundemantals but understand a chart that looks promising, (usually too late to get best sp) and read what others write on the bb's BUT have also learnt the hard way to put a pinch of salt with some commenters...(not you cynic) as they seem to have thier own agenda. Most on here are very helpful and know a lot more about a company than I. I like to think my contribution helps....not the sp, but to lighten up what can be some dull days, I'm sure they think I'm a complete plonker (thanks cynic) and they can tell me to p*** off if they want.......won't make any difference though....lol.,.

Oh Cheers, you have made by evening, going to sign off now as been on this dam thing all day and have had enough, better day tomorrow all round and good night. (I too cannot work out the fundamentals so be it we cannot all be knowledgeable about everying in life). Just plod on eh!!!!!!! Non of us are too old to make mistakes. I to have found the vast majority extremely helpful since I started.

Thanks for your reply.

3 monkies - sorry to see this did not get to the level you need today dudess, i know what its like to buy in too high then effectively be stuck or take a hit - not that often nowadays thankfully - but one of the last times was a year or so ago with strangley pyc (& ntog but that spiked nicely in the end!) pyc was a dog for me for a while - locked into the darn share till one day - a spike!! i got out immediately at just under break even and it tanked again that day to a similar low level it started at - i am saying this really to say if you do end up locked in just sit tight if you can afford to - the guys on here are correct and i stated it myself on oxb oxford bio that one of the reasons i dont normally bother with pharmas is that they are darn slow to come to market - pym is another i messed up on pharma wise - in the end after being locked in they did a fund raising at 10p i seemed to remember and that was a huge help to get me out - sar i honestly believe have a very good prospect as do many medical boffins - however can take time to be approved - BUT each step nearer to this will increase the SP large - try and sit tight - avg down - if you did that may want to wait i feel it might be south more than north here tomorrow but i might be completely wrong!!! good buys right now otc, sres, rgm,rrr, rrl, and many others others but may take some weeks for some to go north again as news flows in - and if you want a gamble - jjb, 888, rem, opm, vmp & others very high risk though imo
sar not a bad share - but timing of the essence
have a good evening and i hope for a better day for you tomorrow

3ms - just saw your post 39 of 40 - mistakes - yep we all do - remember 'someone who has not made a mistake has not made anything'
cheers

BB

P*ss off

:-))

I know you love me really....xx

sres today!?

pth / bb - lol! u nutters!

This should cheer 3 monkies, a shortage of stock it would seem.

he Company announces that, following investor demand, it has conditionally
raised 500,000, before expenses, by way of a placing by Hybridan LLP of
50,000,000 new ordinary shares of 0.025p each in the capital of the Company (the
"Placing Shares") at 1p per share, representing a 40 per cent. discount to the
closing market price of 1.65 pence on 8 February 2011, the price which formed
the basis for the Board's decision to undertake the placing. The Placing Shares
have been issued to Xcap Securities plc, on behalf of its clients.

Following the results of the recent study that was announced on 7 February 2011
Sareum intends to use the proceeds of the placing to accelerate the advancement
of the Aurora+FLT3 Kinase leukaemia drug discovery programme and for working
capital generally.

Looking really bad for anyone in yesterday....long haul now.,.

If you check yesterdays trades a punter bought 2m @ 4.05. A bad headache today I would have thought hope it wasnt 3m.

Yep! your correct there Ballerboy - sounds about right for me!!!!!! Thank goodness something else is going good. PYC gone as well. Thanks kim for the message earlier. One never knows they may (live in hope) accelerate the advancement of the lukemia drug as it costs a fortune either hospitalising or nursing homes to treat such patients whilst they are on a certain steroid treatment for such a condition, I only know as I lost my Mother-in-law who had it last June. Never mind about the share it will do one thing or the other.

3 monkiessorry if this has been asked beforewhy have you left the wise out?.although I cant guarantee you will see no evil on here? Anyone seen Cynic?

No driver it wasn't me thank goodness, I have never had 3m. shares in anything - wish I had in RRL though - I certainly wouldn't be watching 'Stock Watch' now.

3 MONKIES - I MAYNOT BE WISER , hold your pateince with any stock .no point chasing stocks and losing wait for the next one . follow some system. this share i was about to buy on the up but did not chase it expecting to dip .so everything dips unless on VIAGRA . more experienced posters on this site .how much time have you got if you have time wait and follow director buys .

Im certainly not wiserbut this is a mover that will definitely shake you!they have begged borrowed and busked to stay afloatthey can be heard on a Saturday banging out old Wham numbers outside The Watermill Rumour has it that they still owe 69p on a bunsen burner they bought at a Cambridge boot fair?it was their only form of heating who chases money from fractions up to 4p?buskers? not for the faint-heartedand the very best of luck to all involved.forgive me 3 MonkiesIm the village idiot!lol

Thanks chakli - Perhaps I should have shares in a VIAGRA company then (oh! sorry, just my sense of humour) one I believe has to by patient wilst waiting for them to work, oops what have I just said 'I believe'. I really did not intent to chase them, I would not have bought if I had had the chance to press the button myself but like I said I will never rely on The Halifax again. One of those things to put down as experience.

I do apologiseIve had a glass or two of wineI cant hold my drinkand think the fourth bottle was a mistake?trouble isafter the fourth bottleyou truly believe people are laughing along with youanyway I never bother with viagraI always screw up!

Just having a g and t myself or two - so pleased you always screw up, it saves on the complications which the Viagra can have ooooooooooops!!! enjoy. I am laughing along with you thought it was hilarious actually, don't apologise on my behalf. I may be as the NHS class as a geriatric (over 60) but I have a wicked sense of humour - so my friends tell me anyway!!!!!!!!

Thats not what I heard tabs.......

4 bottles of wine and a Snake Charmer springs to mind.

Nah....tabs doesn't blow and suck on pipes......tone deff.,.

Baleryou always were troublemixing with that bow-legged Tour de Force Cyclist too longhow he sits on that saddle?..(_!_) Anywayon a more sensible notelets hope the SP climbs to 5p tomorrowand you all get out with shed loads.......................
perhaps that wasnt too sensible a note?but its the best I can do before I fall overgood luck tomorahhhhhhhhhh!

I might be a plumber?

lol....are you celebrating on a good day trading, or is this just another day??

tabasco - only 4 bottles of vino - taking it easy today then! enjoy dude

Baleras you knowI laugh my way through life.it was just another manic dayfunnily enough the wife thought I had made a lot of dough?

Gibby4 bottlesI wish!

3 monkiesIm a charmerand not a snake.the very best of luck todaymay your wallet be as large as your smile

Cheers tabasco, same to you.

Something has been leaked?

Hope it leaks a lot more, in the right direction.

BUY SAR THE NEWS SHOWS IT IS GOING TO ROCKET

3m

More like a big ramp going on don't get sucked in.

No insider knowledge there then!

yeeeeeeeeeeeeeeeeeeehaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

great rns - gonna end the day over 3p!!!!!

Sareum report positive tests on cancer drugs
StockMarketWire.com
Sareum, the specialist cancer drug discovery business, has announced positive results from pre-clinical in-vivo efficacy studies from their joint research collaboration with Cancer Research Technology and The Institute of Cancer Research.

A recent colon cancer pre-clinical model study carried out demonstrates that the combination of a collaboration Chk1 inhibitor, dosed via the oral route, in combination with a chemotherapeutic, gemcitabine, demonstrates a greater than two-fold reduction in cancer growth rate compared to treatment with the same dose of gemcitabine without the Chk1 inhibitor.

Sareum's CEO, Dr Tim Mitchell, commented: "These are exciting advances, demonstrating efficacy of our Chk1 compounds in several cancer models. Studies on additional models are on-going. We believe the results from the recently conducted studies will significantly enhance the licencing package and assist the collaboration in selecting the best compound for development into a clinical trials candidate".

Taken a punt in this, pure gamble....not sure at all....but will be patient (no pun), until decent profit emerges.....

Could easily go to 5p......volatile....

Kudos to Gibby who quite accurately predicted the SP finishing over 3p today :p

Well done all those in at low levels
D

Small profit showing......will this turn out to be a star ?.....could go much further on monday !...

3m's your luck might be in......keep watching.

Who knows, throw a coin up in the air as they say - better than nothing though, keep everything crossed this weekend and see what happens. Balerboy I sold PVC - lost 52.50, I spied my chance and sold for 0.52 - watch this space they will go up now haah!! I'm not bothered I'm out. My friend made a few bob this morning with sar which I am more than pleased for her.

Have a good weekend all.

Sorry I meant PYC - did you get out ballerboy?

missed it, had to go out.....sods law..lol

I really hope that my luck is in with Sar BECAUSE IF EVER I MAKE A PROFIT

we'll meet in yr local.....

You might have a long way to travel and your pouch might not get on with mine oh dear too many gins uuuupppppppsssssssssssss.

Drug group Sareum soars on cancer inhibitor news
Sareum, an Aim-listed drug discovery company, has more than doubled after positive results from a pre-clinical trial of its cancer treatment.
The company's Chk1 inhibitor, when combined with chemotherapeutic drugs, showed a more than two fold reduction in cancer growth rates, compared to using the chemotherapeutic alone. The cancer growth inhibitor was developed in collaboration with Cancer Research Technology and the Institute of Cancer Research. Sareum chief executive Tim Mitchell said the studies demonstrated the efficacy of its compounds in several cancer models, and trials on other models were continuing. These are still early stages - there is no licensing agreement as yet for example - but Mitchell said:
We believe the results from the recently conducted studies will significantly enhance the licensing package and assist the collaboration in selecting the best compound for development into a clinical trials candidate.
Early stage or not, the market likes the latest developments, and Sareum's shares have jumped 1.34p to 2.39p.


http://www.guardian.co.uk/business/marketforceslive/2011/mar/04/sareum-soars-cancer-inhibitor


http://www.growthcompany.co.uk/news/1607738/sareum-announce-latest-update.thtml

In the know: Capita, Sareum Holdings

* The Times
* Published: 05 March 2011
* Markets

...sector business. . Tiddler to watch Shares in Sareum Holdings more than doubled, rising 1p to 2p, after the drug discovery company said that its cancer growth inhibitor...

I think the word flat was a typo..lol some coverage today though...

MARKET REPORT by GEOFF FOSTER:

Cancer drug discovery company Sareum was flat at 2.38p after revealing that its cancer growth inhibitor therapy had shown positive results in pre-clinical trials. Apparently, when its inhibitor was combined with chemotherapeutic drugs it had led to a greater reduction in the growth rate of colon cancer than did the drugs alone.

Read more: http://www.dailymail.co.uk/money/article-1363155/MARKET-REPORT-GEOFF-FOSTER-ITV-tunes-Footsie-elite.html#ixzz1Fi3ymTMp

double post.

It could do what Provexis sp did a few years ago, next week, (soaring to 10p) or so because this is a major result by this small company !.

Certainly a good result at last for this little bioco. I held years ago but then sold as it seemed to be running out of cash. P'raps time to get back in now?

I like this post from another bb.... Opinion: Strong Buy
Price: 2.38
My Views on Sareum..in a nutshellToday 02:27

(a) It is currently oversold after spike in mid Feb and the market cap is still low at 28-32 million ...say compared to Phytopharm with a single 43% Phase 2 cure for Parkinsons and capitalised at a couple of million more

(b) The trial results are exceptional - 1 in 100 potentially successful drugs fails to get to pre-clinicals...the fallout for Phase 1-3 is statistically less and usually the pre-clinical gives a hint of failure eg 20% efficicacy..here we have a PRE CLINICAL 100% cure, see (f) for the reason why... which is the real reason for us all to stay invested

(c) Cancer cures is a potentially multibillion market

Now for the biggies

(d) despite the buzz on here probably no more than 30,000 people in a world of 7 billion are FULLY aware of the signifigance of their methodology and the outcome of the trials.. as the news spreads the investment will increase dramatically

(e) The company has no major institutional holders...with its sudden burst in size all the AIM / small cap funds need to buy some and they should by now all be tightly held by PI's who have seen 100-200% gains and haven't taken thethe profit REASON they have reached the logical conclusion that this is a multibagger like no other.... so demand will exceed supply and the price must therefore rise almost inexorably....well to the point where everyone can see the emperor is bare....this could after all be the South Sea Bubble of the 21st century!!

(e) The company is not a one trick pony..the second RNS confirms the power of the STIL platform....from the identification of a problem to tackle and the formulation of a strategy to preclinical success takes on average 6-8 years....SAR floated in late 2004 so 2011-3 is the period when the initial products will come home to roost...this is the first two of the initial products and there is a pipeline of other targets which they have started to tackle over the last 6 years which we are not including in the valuation

(f) The biggest asset the company has is the technology to identify the disease cause and the molecule to solve it...this can be rolled out for hundreds of diseases....the building of the magic bullet and the testing of it are time consuming but relatively simple....so in effect YOU ARE NOT investing in a cure for myeloid luekemia but rather in a cloud factory to produce the CURES to many diseases.....and healthcare is the only part of the economy in the UK or the world which is not being cut back at the moment

IN SUMMARY SAREUM's DIAGNOSIS AND DESIGN PROCEDURE IS BIGGER THAN E-PROCUREMENT / RDIF / ALTERNATIVE ENERGY and SCARCE MINERAL RESOURCES PUT TOGETHER.

DYOR

Going by this : 5 to 10p next week ?....I'd like to think so, but surely a rise by a penny is in the running on monday .....hope so...

Is Tabby in these? We are sunk if he is! ;o)

Nah! Only joking Tabs! :0)

SAR has a very good chance of strong interest from potential licencees now. Nothing guaranteed as always with research companies like this, but it cannot be ruled out as a potential 10+ bagger from here on.

required field

This could go anywhere but I would keep my finger over the sell button If I were you, This is being ramped by day traders, keep in mind SAR has a bigger M/Cap than ASM who have 23m in cash and five products on the go not holding either by the way just an observation.

A bit of a sob story for you Driver. I have been in these for longer than i care to remember. On Feb 9th the sp flew and I decided to sell a majority of my holding for 4.6p having bought substantially lower; pressed sell and sat back with a satisfied grin, at which there was a flash and a bang and the electric cut off. By the time the power had been restored the sp had fallen to 3.1p and my sell order had failed! Sold at that price, without a grin! Still holding 150k. Not a lot but staying with the potential. (Ramped or otherwise!)

kim
LOL Stick with it, Good Luck

Kim.I am Mr. luckyyou should know thathad my best year ever last yearand this year has started the same.
First of all let me thank 3 monkies for putting this dog back on my radarthank you!...
10 years back I was invested in millennium pharmaceuticals on the nasdaqI dont even know if they are still going?...around 2003 they pulled out of the UK and SER were spun outI yhink?...those with better knowledge can correct mewhat a bad stockbegged, borrowed, gifted moneydownsized operations.you name it investors covered it
Then on the 07/02/11 we had the positive results from leukaemia studythey looked good and made a few of us take noticesome paid over 4ptoo bigger risk for me
After tgree big daysthe price kept dropping..why?
Kim when the SP flunked to 1.30p on no other newsI thought it was fcuking mentaland took a punt
Within a few days down to 1-05pI thought I was fcuking mentalthen came the second bit of good news Dr Tim Mitchell, commented: "These are exciting advances, demonstrating efficacy of our Chk1 compounds in several cancer models. Studies on additional models are on-going.
I dont believe in coincidencesthis works in two types of cancer.fact!!!
Kimwith me investedyou should feel lucky.I have spoken to a guy today that assists in my luckhe reckons it will hit 4p tomorrow at some stageenjoy the ride!

Thanks for giving me an acknowledgement tabasco - will try and buy some more early tomorrow to get my initial awful price down which the delightful Halifax made me pay. Very hard to trade last Friday - would not let me execute a trade again and I certainly wasn't leaving it up to them again!!!!! Good luck all and if I make a profit on this I shall certainly donate some of it to Cancer Research. Don't know now whether I should have got out of PYC.

I hope you all turn out winners. Oh, and me too!

It's what I suspected : going ballistic....

morning all - another good day - plenty of press over the weekend & from the other side:

'I sent another email to Claire Noyce of Hybridan. My Email: Hi Claire, Thanks for your reply, but Tim put me onto yourselves! Can you at least let me know how often brokers target prices are reviewed as Sareum is now well out of date? Kind Regards xxxxx

Claire's reply last night: Dear xxxxx, Again, it is very difficult for me to comment in detail. To keep this non stock specific, i would make two comments. One: there is no rule here defining when a broker needs to move his target and two:Companies don't always want research written for various reasons it might not be the right time. Best regards Claire Noyce

I read this as Sareum asking Hybridan not to report yet and probably because they want the latest RNS to run its course and also they are very close to a deal, which will then make it easier to re-rate the stock! GLA today'

onwards & upwards!!

3 monkies

Did you buy more.

Oh! yes, brought my spread down to 3.20 thought I had waited long enough for them to drop after the rise .......... guess what - didn't wait long enough, but that is typical of me but if there is good news to come I am sure it will come right. Hey ho!

I had my finger hovering over the sell button at 3.1p when L2 was indicating that the sp was going to go ar*e up but did nothing, should have sold and bought back at 2p but there you go. Didn't do it! A bit premature to sell though; if licencees are not forthcoming in the next couple of months then maybe there is a rough ride for SAR ahead. Can't see it at the moment though, these rose tinted specs are pretty strong! :o)

I think I need my head testing as well as the eyes kim - I just hope they do well for the people who suffer and a little profit for me and all of us and certainly some for them. As far as the head testing goes - no comments please I know I'm bonkers........

Oh, I'm sure you're not bonkers 3M just, like me, slightly deluded on occasion! ;o)

Yes, SAR are doing some sterling work to try to find cancer cures, let's hope they have many successes in the future.

Just laughing at myself and thinking perhaps I should have left it up to the Halifax to buy for me they would have probably got them for 0.40 'si less than I did. haha!!

Im not going to comment.


The Company announces that Mr Tim Mitchell, Chief Executive Officer of Sareum,
has today sold a total of 500,000
.
http://moneyam.uk-wire.com/cgi-bin/articles/20110307172000H5143.html

Good on you driver - I don't need you to.

I suspect he wanted to stock up on a few bottles of Louis Roederer Cristal 1999 Champagne Driver! He still has 42,280,471 shares left though in readiness for future celebrations! :o)

At least he wasn't too greedy he could have pushed the button (as if) when they were higher or even in February so I would like to think the stocking up of champers may be the case (or 3). A bottle of Moet would do me.

He'd need to sell more than 500,000 shares to buy 3 cases 3M! We may all be drinking Moet soon though, or a bottle of Magners if it all goes wrong!

I wonder if the Reader's will be selling some of their shares? They have a holding of 3% which was what Tim Mitchell had prior to the sale.

Never wanted much out of life kim, a nice home a car that starts and nice food and of course health. A couple of gins here and there which may be reduced to Magners but at the end of the day we stand as much chance in this as any other share they are all a gamble. Readers probaly will sell who knows??? Here's hoping for the Moet, I'll even sugar the rim of the glass, now that is what I call extravegant. Good luck.

Well that didnt exactly go according to plan...25% up early doors then traders started beating each other up for pocket money...speaking of pocket money...strange time for the CEO to open the till?...I have read the two recent rns over and over...do you know this is going to be a little gem!
If it was worth 2.37p Friday...all the good weekend press managed to devalue the market SP by 12% ...I didnt agree and managed to pick a few more up at a lot less than the Friday close. I just loved the news....fantastic!
Off piste...I was given avct as a good punt Friday...and loaded up...and again today... no thread...no opinion on AM...strange?

I like the sound of you 3m...low maintenance and an alcoholic...bingo...lol

Don't play it - sorry hate the game eeeeeeeeehhhhhhhhhh! Probably be to 'hissed' to even shout HOUSE.

Youre a lady... Good luck tomorrow.

Had a little look at avct (they have gone up quite a lot recently) will look again later, good luck to you as well tomorrow.

Steady tabasco, all visual love making after 9.00pm please.....my kids might see:>))

Baler... visual love..is there any other? Do you make love without looking at your wife...you must be well equipped?.. Are you in the same room?...am I too nosey...why do I keep asking questions?

Don't be surprised if an RNS turns up to say that Drs John & Valerie Reader have sold to bring their holding below 3%, they founded SAR along with Dr Tim Mitchell.

I don't know why they would sell though!

I do hope not, that would make them go down down down. Just been reading again all about them and they are as you know into all sorts of things!!!!|! I wouldn't be surprised if that it is not too long before they have cracked one or two things - hopefully that is of course.

well - retrace was always a possibility - but this is aim lol! but personally it is the next rns or 2 i am looking fwd too more here - sar is on many peoples radar now - in fact has been for a little while - just intensifying now - and imo dont let val slip under the radar - like sar working towards similar goals - today at val 51m buy or 9% of the company delayed trade i believe - getting quite serious there and would not expect the sp to remain as low as it is for much longer apparently!! lol

good to see some quality alcoholics in here!! have a good evening all

Cheersh. Hic!

Call me silly...I have lumped on big time again today...those RNSs are shouting out...and if you imagine fear you shouldnt be in this game...good luck to all..

You are silly :-)

your silly!!

Very Silly!!!!!!!!!!!!!!

Thanks guys...I feel so much better now...

Sareum's CEO, Dr Tim Mitchell, commented: "These are exciting advances, demonstrating efficacy of our Chk1 compounds in several cancer models. Studies on additional models are on-going. We believe the results from the recently conducted studies will significantly enhance the licencing package...

Put a price on that guys?

3 monkies...what about getting a graph and some info on this thread at the top.

.0195p

1.95..............baler...i can be as silly as you...some would say sillier...is that a word?

It is, but I think it's more acceptable to use "more silly".

OK Skinny...i'm more silly...agreed? lol

Sorry - I'm just bored before the game tonight :-)

Have a read of this then skinny...

Sareum Holdings: An early stage drug group with a very interesting future
16th Feb, 11:20 am by Jamie Ashcroft
Sareum was formed in 2004, after the biotech bubble burst but before the financial crisis ravaged the capital markets. Sareum was formed in 2004, after the biotech bubble burst but before the financial crisis ravaged the capital markets.

The junior biotech space has been bubbling with excitement over the past two weeks. And in fact there appears to be the early signs of a renaissance in this cutting-edge sector.

If you are thinking of piling in ahead of the crowd, I have just a couple of words of warning.

Investing in these small-cap drugs stocks is not for the faint hearted. For every Amgen current value US$40 billion and growing - there are ten or more failures.

It is a roller coaster ride punctuated with failure more than success. So, you need to take a three-to-five year view.

That said, when these stocks take off, they do so spectacularly - you only have to look at recent performances of ValiRX (LON:VAL) and Sareum Holdings (LON:SAR), a company we here at Proactive Investors believe is a very interesting play in the biotech space.

It operates in oncology, which is the sexy end of drug discovery. Short of finding a cure for the common cold, a breakthrough discovery for cancer represents the Holy Grail for researchers and investors alike.

Hundreds of companies and thousands of scientists have devoted millions of man-hours to the quest. What we have, however, is a hodge-podge of life extending drugs and a couple of anti-cancer vaccines.

The urbane Jean-Pierre Garnier, the former boss of Glaxo, once said oncology products were progressing so fast that cancer could soon be managed as a chronic ailment rather than a life sentence.

Sadly, the latest wave treatments have failed back up this rather bold assertion.

However such is the interest in this particular area of medicine that any company making progress with a treatment for cancer is deemed hot property.

The performance of shares in Sareum is a graphic illustration of this.

It is in the early stages of developing a treatment for leukemia, a disease which kills over 200,000 people in the developed world each year.

Last week it published some pre-clinical data. Remember this is very, very early stage stuff yet the stock was like a runaway train.

The share price rocketed over 1,600 percent in just three days, rising from 0.275 to 4.79 pence.

Okay, the companys results look very positive. An in-vivo study of Sareum's Aurora+FLT3 Kinase programme, targeting the most common form of adult leukaemia, showed that the leukaemia had regressed to such an extent that no detectable cancer could be found in any of the cases treated - ten in total.

By comparison, leukaemia increased five to fifteen fold in the study examples treated without Sareum's compound.

Here we take a deeper look at the headline grabbing biotech junior. Proactive Investors spoke to Sareums founding director and chief executive Tim Mitchell.

Reinvigorated after weathering the financial storm

Sareum was formed in 2004, after the biotech bubble burst but before the financial crisis ravaged the capital markets.

It was spun out of Millennium Pharmaceutical when the American oncology specialist wrapped up its UK operations.

Mitchell, Millenniums director of structure-based discovery, founded the new business alongside Doctors John and Valerie Reader. Between them, Mitchell and the Readers, are the companys largest shareholders with 3.1 percent each.

Back then Sareum took a two-pronged approach.

It owned its own laboratories where it carried out in-house research on early pre-clinical stage drug compounds. Meanwhile it hired-out its spare capacity to work on other research on behalf of larger pharmaceutical firms.

The in-house research soon took a back seat and over three fairly successful years Sareum built up its service division. By 2007 it had 35 staff and it was turning over 35 million a year. Indeed the service division quickly grew in stature and at its peak it was handling more than 20 programmes for a variety of firms - including industry giants Roche and Johnson & Johnson.

Just before the financial crisis began to bite Sareum was almost breaking even, with its small losses being supported by modest capital raising in the AIM market.

The plan was always to use the service division revenues to support the in-house drug development until it could land a licensing deal and bring its own drug development to the fore.

For Sareum the tough years that ensued amid the recent financial turmoil presented a notable silver-lining, as it ultimately brought forward these plans.

The bottom fell out of the services market for a while, particularly in the US, and the AIM market wasnt in terribly good shape either, Mitchell said.

We were both struggling to earn money and struggling to raise money. We had to undergo a major rethink and restructuring.

Mitchell adds: This essentially brought forward our plans to concentrate solely on our internal research.

As the capital markets dried up and many of its peers went to the wall, Sareum sold of its service division for 720,000 in August 2008. It then striped back its remaining operations, closing its labs as part of the process.

In doing so it has created an efficient virtual organisation that outsources all the research work on its proprietary drugs compounds.

We operate out of an office now (rather than a lab), Mitchell said.

It keeps our costs low if we have to, but it is very flexible as we can turn-on the research as and when we require.

Indeed a quick glance at the stocks chart even before last weeks explosive rally suggests that Sareum has weathered the storm and after a relatively quiet transitional period it has once again burst into life.

The leukaemia study

With its newly restructured, and efficient, operation Sareum has been quietly getting its head down, progressing a number of pre-clinical research programmes into a variety of new drug compounds.

The latest results from the pre-clinical Aurora+FLT3 Kinase programme propelled the stock to more than a 1,600 percent gain last week.

Mitchell surmised that it was a standard pre-clinical test, using model systems where a cancer is induced and the drug compound is then applied to try and get rid of it. The tumour was measured every few days and compared with the untreated cases.

We got a very very good result, Mitchell said.

In the treated cases nothing was able to be found. Although that doesnt mean that the cancer wasnt there it was just too small to be detectable.

The experiment then continued with no further treatment to the tumour, to see whether it grows back.

Mitchell adds: It did grow back in eight of the ten cases, but not in two. This is still a great result.

The best result would be that the cancer never came back in all ten cases. But with another round of treatment we may get that ten out of ten.

Indeed the result was undoubtedly a game-changer, as least as far as investors were concerned.

Mitchell reckons the results stack up well against a number of more advanced drug candidates that are being developed in the clinic by his competitors.

He said that Sareum tries to compare the results as best it can against other similar drugs that are in development, although he notes that not all experimenting conditions are the same.

Against similar compounds that are already in early-stage clinical trials our result is at least as good, and while they might argue in our view theyre better, Mitchell said.

We see an advantage. Our results seem to be forming better than those that are out there in clinical trials, when they were at this stage.

However Mitchell stressed that there is still plenty of follow up work to do.


Full story...http://www.proactiveinvestors.co.uk/companies/news/25583/sareum-holdings-an-early-stage-drug-group-with-a-very-interesting-future

No dirty talk before 9.00 p.m. tonight tobasco, children might be watching. Thanks for posting the above saved me a job, as for a graph, I have not got a clue how to do one!!!!!!!!!! and I can't be a...d even learning how, not a brilliant day on this but early days. G & T time so good night - oh! my friend made a few bob out of LEG today in and out early so she is a happy bunny and she can't do graphs either. Cheers all.

Kim it might be home brew next week hahaha!!!!!!!!

I'll get my kit out of the attic 3M!!! :0)

One of them thar charts like the one above would sit well at the top of this page 3M! I'll tell you how to do it if you aren't sure.

It would be nice to know despite the fact I said I couldn't be a....d! Thank you for the offer of helping me. Could you send your chart up to the top of the page, I am sure it would be easier if you would not mind of course "if that is acceptable to others". Look forward to seeing what a balls I make of trying to work how one does it out. Cheers and hoping for a good learning process and a good day tomorrow.

KIM YOURS IS TO BIG.

Very good, then I shall leave it up to the experts because whatever I did everybody would critise. I hope that Kims bank ballance one day is big enough to not even worry about having to do charts, kindly offering me the chance to learn how to do them and is sunning herself wherever, either being with a chilled Magners or the tipple of the day whichever takes her fancy.

Sorry, I was gramatically wrong 'critisise' - "criticise" was the one. I would really appreciate your knowledge on teaching me how to do a graph - kim, whether it be BIG OR SMALL. Probably trying to teach me on this BB would not be feasible.

Gosh, I would hate to give some of these clever folks the chance to pick me up on the Queens English. Good Night and 'Hic' once again.

Thanks Driver, it's the first time anyone has said that mine is too big! ;o)

Erm, sorry 3m, I'm not a laydeee! Like Driver, I'm a fella. You are not the first to be confused by my pseudonym! It was my daughters who insisted that we should remember our much loved/missed dog Kim by my use of her name like this! My real name is Steve, call me by whichever name you wish (my wife usually does!!).

I wouldn't dream of critisiz.....crittisisin........criticissi......um, saying you are gramatically (or should that be grammatically) wrong ;o)

To be fair, I do have the advantage of spel checkur. :o)

So.....to charts, be they big or small:-

Scroll to the top of this page and you will see "Charts" 4th on the right from "Stockwatch", click on that then enter SAR in the "Stock Symbol" box. If you want a 'big un' simply click on "Draw Chart" on the bottom right hand side of the box and voila, a lovely chart showing SAR's progress (or otherwise!). Scroll to the bottom of the chart and you will see "Paste Chart to Bulletin Board..." click on that and follow the instruction (copy and paste). You can adjust the "Range", "Size" etc of the chart as you wish; have a fiddle about with it and post whichever you like the look of. Let me know if you have a problem.

Unfortunately I am not a 'chartist' so cannot offer any advice on the chart itself other than the "Live Intraday Charts" can often (but not always!) show the likely trend for the day and is useful when run alongside Level 2. Only my opinion that though!

Click on the pencil and paper to the right of the date and time in your header to add a chart.

Off piste....

Could any kind person with neutral views please start an AVCT thread.....the link below profiles CEO Alastair Smith and gives a pretty good snapshot of Company progress...including a terrific partnership deal with American marketing giants...Pall Corporation [$6.3bn market cap] I hold my hands up and admit to being invested...but opinion and debate most welcome...a possible take-over target....Kim..Skinny...3m et al .....Pretty please...


http://www.yorkshirepost.co.uk/business/jobs/profile_alastair_smith_technological_tie_up_opens_up_a_whole_new_world_for_avacta_boss_1_3155677

Two big trades totalling 13,400,000in after hours...1.93 and 1.95p... SPs that were well above todays prices...Interesting to note that was almost the entire registered sells total today?

Two quotes from the CEO that cannot be forgotten...

Mitchell surmised that it was a standard pre-clinical test, using model systems where a cancer is induced and the drug compound is then applied to try and get rid of it.

The tumour was measured every few days and compared with the untreated cases.
We got a very very good result, Mitchell said.

In the treated cases nothing was able to be found. Although that doesnt mean that the cancer wasnt there it was just too small to be detectable.

CEO Tim Mitchell insisted there is the 'potential for a deal that will transform the company' and bring about a 'big positive change.

Patience, Tabby, patience! If this is destined for big things then so be it, it will happen. Do not put the house on it though, not yet. Should be good for a short term gain.

As for AVCT, well the same applies, though they at the sale end of things. Their last Interim Results Notification and Trading Update was a little cautionary ("Whilst continuing to grow substantially, turnover for the current financial year is anticipated to be lower than previously expected with marginally greater pre-tax losses.") and that may well hold the sp back for a while. Good potential however, so long as sales can be maintained, obviously. Definitely worth keeping an eye on, so thanks for bringing it to our attention.

Kim...I am an investor...patience comes with the job....but when you read statements such as
An in-vivo study of Sareum's Aurora+FLT3 Kinase programme, targeting the most common form of adult leukaemia, showed that the leukaemia had regressed to such an extent that no detectable cancer could be found in any of the cases treated - ten in total. Ten out of ten aint a coincidence...I dont think you are going to need patience here Kim...I expect a number of door knockers rapido!...
With Avacta... the exciting news for me was the tie-up with Pall Corporation... $6.3bn market cap along with AVCT orders of Optim this year already doubling last year sales...

ref post no. 94.
yet another after the event, with full descriptive reasons for buying and not selling out that can only be so accurate from hindsight, in my opnion. is it little wonder that those that are past post posted deny it and insist that it is simply luck. try saying that..-)
after all if they got caught out they would be in serious trouble. fortunately not many can be bothered.and anyway even if they could they would probably be shouted down so loudly and bombarded with either abuse or proof as to the contrary that they would most likely give up. bit like me.i surrender.
all just my opinion as always.
good luck to all
regards
jkd

JKD...I can only take it as a compliment that you follow me so closely round these bbs...I have to say your post concerning this stock is correct....I have always kept an eye out since the Millennium days....SAR have always performed terrible!
The announcement made on 7 February 2011 moved the price up many multiples...only to close at half the days highs...I was having a laugh with m3 et al on the 11th after a further decline when I actually read the full announcement...it was actually really good news...stunning!
JKD...I had missed the boat...could have bought for fractions of a penny...ended up paying 1.29p and change...it looked like a mug punt when SAR quickly fell back to a 1p...
I have since loaded again at 1.91p and change...I aint been clever with this stock...never pretended to be...and have placed all my bets after the initial news...
JKD...I could just be a thicko on this one...time will tell if I can add lucky?
To all other posters...apologies if my posts have deceived in the manner JKD is claiming on this thread...good luck holders...

Is this some news on the way....very difficult to buy big?....

Don't know it would be nice if there was.

http://www.iii.co.uk/tv/episode/sareum-sar

So a 4th place finish in todays top list...nice on a down day... no surprise if RNS tomorrow...

Posted on another thread...you can probably take it as a blatant ramp...but carefully worded and an interesting view....


MD...I have been associated with the industry for some time, mostly around post licensing surveillance and partnership facilitation. Just to be clear...I have not heard anything from Tim or anyone who is employed by Sareum directly. What I do know is that Tim and friends value this company very highly (in cash terms) and had no interest in encouraging a t/o...I understand that recent discussions..that I believe are far more than preliminary chat...have led to a change of focus. The fact that the firm interest comes from more than one area will push up the price to a very significant level.

Feel free to speculate about the offer price...but imho it will be very high indeed. The only sticking point will be the IP (and related protection) not yet in the pipeline. I would guess that the press will pick up before too long on the likely t/o...and then we'll get a RNS.

Looks like news is coming....big step up in interest at the minute...

Whooooooooooooooosh!

Second on the top list...the last positive update came on a Friday...a big rumour on another BB... relentless surge from 2-30 right to the bell...what do you reckon folks?

1 SCHE Southern Cross 13.50 40.63% 3.90
2 SAR Sareum 2.48 33.78% 0.63

Don't know what to make of it Tabasco - we will have to wait and see but I am convinced some good things are going to come out of this.

Equally convinced! This just might be one of those companies that makes it through the jungle.

How come it's gone soo quite in here? Am I missing something?

Only that they are going down - from what I can see they are not on their own!!!!! Suppose it is another game of patience.

Very stange how it shot upto around 2.5p and wouldn't go under 1.90 for no apparent reason. Gone back down now though...

Either they are being very cautious who they choose for a licencing partner, or a licencing agreement is not forthcoming. I would like to think that it is the former and they can't make up their minds whether to go for GSK or AZN (or a company of that calibre!).

Perhaps still a little early, but I'm starting to get itchy feet here. Have SAR got a cure? :o)
C'mon SAR, RNS in the morning PLEASE!

I hope they heard me. ;o)

Kim...your wish!...

More leaked news?...A lot of activity all of a sudden?

Lol! Interesting Tabby!

That was quite strange! I think everyone needs to ask for an RNS!

Altogether now......................Where's that RNS???!!! :o)

Did a few test sells late on, my broker consistently offered more than the stated bid price which made me think that they had wind of something positive. I shall be soooo cwoss and stamp my 'ikkle feet if I am wrong!

Kim...Last seven sessions have shown an average of around 15mil shares traded...93mil today?...must be just a coincidence. Bound to go down tomorrow...I dont think!

Also... halfway through the day only 11mil shares traded...so why the afternoon mad rush on no news?...must have been corkscrew carter...straight as a dye?

Time will tell!

Update from their website.

level 2 strong right now http://www.sareum.co.uk/base/images/pdfs/SareumMay20052011.pdf

4.2p fair value

Just sold half at >100%. Should have done so on the last up.

well done - bit early to sell yet - l2 very strong buying but understand why some going too early - gl

could be a 50% + peak

Gibby - I have more than my original stake back and am happy to let the remainder run - a policy I try to adhere to with "tiddlers".

good policy

profit takers about right now

Looks like Sar's running out of steam?

The boilers been stoked!...

Preclinical Development Candidate Selected for Chk1 Inhibitor Programme
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TIDMSAR

(AIM: SAR) 15 August 2011



SAREUM HOLDINGS PLC ("Sareum")

Preclinical Development Candidate Selected for Chk1 Inhibitor Programme

Sareum, the specialist cancer drug discovery business, The Institute of Cancer
Research ("the ICR") and Cancer Research UK's commercial arm, Cancer Research
Technology Limited ("CRT") are pleased to announce the selection of a

preclinical development candidate from their joint research collaboration.

The joint research collaboration targets Chk1 (Checkpoint Kinase 1). Chk1 is
important in controlling a cancer cell's response to DNA damage, which may be a

consequence of the cancer itself, or intentionally caused by chemotherapy or
radiotherapy.

Preclinical model studies carried out at the Cancer Research UK Cancer
Therapeutics Unit at the ICR demonstrate that the Chk1 candidate, dosed via the

oral route, in combination with the chemotherapeutics gemcitabine or irinotecan
significantly reduces cancer growth rates compared to treatment with the same

dose of chemotherapeutic without the Chk1 inhibitor.

Further preclinical studies demonstrate the potential for the collaboration Chk1
development candidate to reduce tumour growth when given as a sole treatment in

models of certain cancer types that are believed to be dependent on Chk1 for
survival.

Sareum's CEO, Dr Tim Mitchell, commented: "The selection of a preclinical
development candidate is a major milestone for the collaboration that will

significantly enhance the licensing package. Our research indicates that the
selectivity and oral dosing properties of this candidate give it a competitive
advantage."

Professor Paul Workman, Director of the Cancer Research UK Cancer Therapeutics

Unit at the ICR, said: "The significant progress made so far is very pleasing
and highlights the value of partnerships between industry and academic drug

discovery groups like ours. There is further important development work to be
done so that patients can one day benefit from these drugs, and we look forward
to the progress of the compound towards the clinic."


Dr Philip Masterson, Associate Director at Cancer Research Technology, said: "We
are working to select the right commercial partner to take the Chk1 programme
into clinical development. Our ultimate aim is that one day, this drug will

become available to treat a range of cancers and save more lives from the

disease.

Our scientists have shown that this drug is promising in preclinical studies,
and we hope further research will prove that it can be used on its own or
alongside chemotherapy and radiotherapy to destroy cancer cells in patients."


For Further Information:

Sareum Holdings pl

No 1 on the LSE top listhot enough?

Certainly a step in the right direction Tabby. "One small step.........." etc!

Sareum Holdings plc

("Sareum" or "the Company")

Final Results

Sareum Holdings plc (AIM: SAR), the specialist cancer drug discovery business,
is pleased to announce its final results for the year ended 30 June 2011.

Operational Highlights
* Significant progress on the two most advanced cancer programmes including
positive in-vivo efficacy data from Chk1 and Aurora+FLT3 programmes
* Nomination of preclinical development candidate for Chk1 in August 2011

Financial Highlights
* GBP950,000 (before expenses) raised by way of three share placings
* Cash at bank and in hand of GBP871,000; sufficient cash resources for
foreseeable future, based on current spending levels
* Loss on ordinary activities (after taxation) GBP568,000 (2010: GBP569,000 loss)
in line with expectations

Tim Mitchell, Chief Executive Officer of the Company, said: "The announcement of
two successful in-vivo efficacy studies, and the selection of a preclinical
development candidate, bring Sareum closer to the commercialisation of drug
candidates from our in-house development pipeline. We are currently actively
seeking to license these programmes in order to allow us to drive forward other
programmes that have been generated from our SKIL platform.

The placings during the course of the year, which raised a total of GBP950,000,
have provided us with sufficient working capital for the foreseeable future to
continue the current level of development of our in-house programmes."

Thanks SkinnyThere are four statements by SAR that convince me this investment is sound :-

Significant progress on the two most advanced cancer programmes including positive in-vivo efficacy data from Chk1 and Aurora+FLT3

Sufficient cash resources for foreseeable future

Two successful in-vivo efficacy studies, and the selection of a preclinical
development candidate

We are now actively engaged in talks over potential licensing and co-development agreements with interested parties.

With the present state of market confidenceI would suggest this a great stock pick!

well no bad news really but only problem with pharmas is they can take an age to get anywhere due to the nature of their business - looks good for the future perhaps

Good news from Sar, hopefully more to come... Certainly seems like it!

On the move up again.
News coming??

Have not posted on MoneyAm for ages. This is the first share I have bought to hold in 10 years. Have been buying SAR since May 2011.

Anyone else currently in SAR?

@Howard0181 yes there certainly was a lot of movement around that time.

Shareprice has been very quiet, needs another RNS to liven it up I think..

Good luck Howard!

Rns out tomorrow, expecting good things for SAR!

Can't wait. Are you still around Tabasco? If so hope you are well.

Research Update.

Half Yearly Report.

Financial highlights

The Company has traded in line with the Board's expectations

Loss on ordinary activities (after taxation) of £327,000 (2010: Loss of £258,000)

Cash at bank at period end was £530,000 (2010: £621,000)

Operational highlights

Programme research and commercialisation making good progress

Pre-clinical development candidate nominated in Chk1 programme

Chk1 programme presented at major international cancer conferences

3m your post 192
if price rallies from here he will probly still be around .if not, he probly wont.at least not in that guise.
good luck to you.
regards
jkd

Good luck to you to jkd whomever you are.

Well, well then, up 0.95 on todays news - it was flying before the news came out so how come everyone knows before we do as to what is happening??? A vicious circle. However looks like if they get a partner it may do well.

Clear as mud :- Drug Discovery – Cancer & Auto-Immune Disease Drug Programmes

It has taken a long time to find a partner, they started looking in March last year, they are either very picky or what they have is not too tempting. Perhaps they are simply asking for too much in return. Time will tell, let's hope it is a short time not another 17 months!

SAR having a good day today, recouped y'days' profit takers. only need it to reach 2.14p to break even!!

Just over 3p for me I am afraid, at least it is on the move.

some life here.

3M could you put a chart in the header.....please.,.

cracking today

A small chart as a temporary measure whilst 3m is away on her hols soaking up the sunshine!

Final Results

Operational Highlights

Significant progress on its drug research programmes including:

nomination of a pre-clinical development candidate from its Chk1 programme
positive in vivo results from its TYK2 programme

Presentations of research data at high profile international scientific and business conferences

Financial Highlights

£252,500 (before expenses) raised through two share placings

Cash at bank and in hand of £511,000 (2011: £871,000)

Loss on ordinary activities (after taxation) £651,000 (2011: £568,000 loss) in line with
expectations and reflecting planned increase in R&D spend

Since the year-end, agreement on a £4m SEDA financing facility from Yorkville Associates (announced 10 September 2012)

Thanks kim for putting up the chart - I still haven't mastered how to do it.

Everything quiet on the Western Front.

I was lucky, sold yesterday.
Negotiations continue, so we should see something early next year.

What is going on with SAR? i am finally breaking even!

Haven't a clue what is going on, glad you are breaking even, I have quite away to go yet. Maybe some news is due and if it is let us hope it is good.

Good news expected very soon that should have been completed by 31/12/12

The company put out an RNS on the 4th saying that it will announce its Interim Results for the six months ended 31 December 2012 "on or before 18 February 2013."

Today's RNS states that the U.S. Patent and Trademark Office has issued notification that a patent will be granted for one of Sareum's key drug discovery inventions on 19 February 2013. The granting of this patent means that Sareum has approved patent protection in the US for key elements of its SKIL platform and many of its drug discovery programmes. It goes on to say that the Company expects to receive similar protection in Europe and other major markets in due course.

It's all about timing with SAR! ;o)

Been wondering should I buy some more to get my spread down or just hold what I have??

Well I sold a chunk yesterday, hence today's RNS and rise in sp! :o)

A little too soon kim but as we know that is my luck - I have to wait until over 3p, that is why I am wondering whether to get my spread down or will it be another load of dead money!!!!!! Decisions, decisions. May be it is better left in the bank who knows as we don't have the crystal ball.

Nothing surprises me with this company anymore so I wouldn't like to guess either way 3m!

Me neither, thanks kim.

Well I did it and got the spread to 2.7673 obviously did not buy a lot but thought the spread would have been less, just hope for the best now and gl to other holders and the people who this company may help (health wise).

Good for you 3m. I hope you manage to get a decent return. I also hope that SAR are not a company who are all noise and no substance. They have been making the right noises for a while now but it seems to fall on deaf ears, though all Biotechs take a lifetime (sometimes literally) to bring something new to the fore. For obvious reasons I hope that they really can make a difference. My son-in-law has been doing various things to raise money for Breakthrough Breast Cancer in honour of his late mother who championed the cause. Another cause she championed was AIDS charities. Tomorrow my son-in-law, who hates the feel and sight (and taste) of any sort of fish, is going to jump into a tankful of sharks, small ones, but sharks nevertheless, to raise funds for AIDS charities. I hope shareholders in SAR will not turn out to be victims of sharks!!

I hope it is not going to take a life time kim and we are not victims of sharks, there are enough walking around, surely something good must come out of this, and as I said at the beginning if I do make anything I shall give it or some of it to a Cancer Charity of my choice. Well done to your son-in-law and hope that he does well.

Good for you and thanks 3m, I'll be filming every minute....he is terrified!!

I think I would need incontinent knickers, he is very brave. Ah! well g and t time, have a good day filming and say good luck to your son-in-law from me.

Will do, thanks! Enjoy the g and t!