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Sphere Medical (SPHR)     

Ruthbaby - 06 May 2012 08:06

Chart.aspx?Provider=EODIntra&Code=SPHR&SChart.aspx?Provider=Intra&Code=SPHR&SizeSphere Medical has 141,757,872 Ordinary Shares of nominal value £0.01 each in issue.


The Wales Life Sciences Investment Fund 25,000,000 17.64%

Woodford Patient Capital Trust Plc 23,125,000 16.31%

LSP Life Sciences Fund 10,904,000 7.69%

Ortho-Clinical Diagnostics 8,141,250 5.74%

Fidelity Worldwide Investments 6,264,649 4.42%

Octopus Investments 6,250,000 4.41%

Ruffer LLP 5,653,895 3.99%

Royal London Asset Management 5,624,185 3.97%

Herald Investment Management 4,711,965 3.32%


Chart.aspx?Provider=EODIntra&Code=SPHR&S


Should be an exciting year ahead with developments.
Anybody had a look at this company?

Ruthbaby - 15 Sep 2012 18:37 - 2 of 71

Interim results due this Thursday 20th September.
Keep an eye out for update on the Proxima 3 device.
This could be a very big money spinner with CE approval..

Ruthbaby - 20 Sep 2012 12:00 - 3 of 71


Sphere Medical CEO Stuart Hendry

Sphere Medical, the Cambridge UK diagnostic device business, saw its first half losses double to £4.2 million after generating zero revenues in the six months to June 30.
But CEO Stuart Hendry and the team insist they have the technology armoury and the strategy to ensure the company doesn’t find itself in a commercial cul-de-sac.

Sphere has a strong pipeline of innovative monitoring and diagnostic devices for the critical care industry.

Dr Hendry said the priority was to secure a commercial partnering deal for its Proxima system – a patient-dedicated arterial blood analyser for use in the intensive care unit and operating room.

He said the partnering proposal had attracted strong interest from a number of leading medical device companies with global distribution capabilities. “Discussions are ongoing and securing a commercial partner remains a core objective for 2012,” he said.

Sphere’s Proxima development programme is progressing across a number of projects – disposable, monitor, software and calibration solutions. Dialogue is underway with the FDA on Proxima including a recent meeting to formulate the regulatory route for full market release of the system.

Despite a revenue-barren six months, the company retains cash and equivalents and money on treasury deposit of £8.3 million (2011: £0.7 million). Operating expenses more than doubled to £4.4m.

Dr Hendry said: “The company’s focus over the first six months of 2012 has been on the continued advancement of the development and commercialisation of our products.

“The process of identifying and concluding a deal for Proxima has been intensive and we are confident of delivering a long term partnership that maximises the potential of this product. We are focused on executing our key deliverables for the second half of 2012.”

Ruthbaby - 24 Sep 2012 08:31 - 4 of 71

Investor presentation this Thursday evening....

**SPHERE MEDICAL INVESTOR FORUM - LONDON - 27TH SEPTEMBER **

The directors of Sphere (AIM:SPHR) will be presenting in London on Thursday 27th September 2012

Venue: Chesterfield Mayfair Hotel, 35 Charles Street, Mayfair, W1J 5EB

The presentations will start at 6:00pm and finish at approx 8:00pm. After the presentations are complete the directors will also be available to take questions during a free canapé and wine reception.

Free to attend.

REGISTER HERE: http://www.proactiveinvestors.co.uk/register/event_details/160

Ruthbaby - 24 Sep 2012 08:33 - 5 of 71

SP has fallen since flotation last November '11.
But some very big medical backers involved here...

Ruthbaby - 25 Sep 2012 17:51 - 6 of 71

Anybody going on Thursday??

Ruthbaby - 27 Sep 2012 20:18 - 7 of 71

Hope some good news reported tonight!!!

Ruthbaby - 23 Nov 2012 10:39 - 8 of 71

http://www.shareprice.co.uk/SPHR/SPHERE-MEDICAL-ORD-1P
Good progress...

Ruthbaby - 23 Nov 2012 13:36 - 9 of 71

Cambridge boost for bypass surgery patients

Technology from medical device business Sphere Medical Holding has achieved positive results in trials with anaesthetists involved in bypass surgery at Papworth Hospital in Cambridge UK.
The results will be presented at the Society for Intravenous Anaesthesia Annual Scientific Meeting in Edinburgh on November 29 and 30 and Sphere hopes it will soon be able to drive the product to market in the UK and Japan.

The Cambridge company reports that Pelorus 1500, the world’s first in-vitro diagnostic medical device for the rapid measurement of the intravenous anaesthetic propofol at the point of care, has met its primary end point in the clinical study. It has demonstrated equivalent performance to a gold standard method of analysis, Sphere says.

A total of 111 whole blood samples from 32 patients undergoing cardiopulmonary bypass surgery at Papworth Hospital were analysed. Each sample was tested using both Sphere Medical’s Pelorus 1500 and the current gold standard High Performance Liquid Chromatography (HPLC) reference test. The results from the Pelorus 1500 were said “to show excellent agreement with the reference method.”

Sphere Medical is working with a number of the UK’s leading anaesthetists to investigate novel approaches to take propofol measurements during infusion with the aim of allowing anaesthetists to know the actual – rather than predicted – concentration of propofol thereby creating the personalisation of dosing to the patient.

Ruthbaby - 04 Dec 2012 14:56 - 10 of 71

Have purchased another 400,000 shares to add to their holding..
Holding was 1,331,081 shares......
Now 1,799,363 shares......

Ruthbaby - 01 Jul 2013 13:33 - 11 of 71

Looks a good tie up...

Ruthbaby - 16 Oct 2013 14:30 - 12 of 71

Starting to create some attention and buying..at last......

Ruthbaby - 17 Oct 2013 12:08 - 13 of 71

There is an awful lot of buying in those trades..even my trades are marked as sells?????

Ruthbaby - 21 Oct 2013 15:02 - 14 of 71

Some blue coming through now...seller seems to have cleared....

Ruthbaby - 22 Oct 2013 08:18 - 15 of 71

Shareprophet has tipped this stock recently....large seller has now cleared.......

Ruthbaby - 17 Sep 2014 16:45 - 16 of 71

Got ce approval for Proxima device....Launching device tomorrow.....
Looks interesting now for a punt...imho....:-)

Ruthbaby - 24 Apr 2015 07:34 - 17 of 71

Woodford's first fund investment.....

Proposed Placing and Open Offer



Cambridge, UK, 13 April 2015: Sphere Medical Holding plc (AIM: SPHR.L), a leading provider of innovative monitoring and diagnostic devices for the critical care setting, today announces that it is planning to raise, subject to certain conditions, approximately £12 million (before expenses), by way a Placing pursuant to which 75,000,000 New Ordinary Shares will be issued at 16 pence each to new and existing investors.

Woodford Investment Management, on behalf of its clients, has given a non-binding intent to invest up to £4 million in the Placing and the Wales Fund (being a fund raising up to £100 million focused on life sciences and managed by Arthurian), has given a conditional commitment to invest £4 million in the Placing. The Placing Shares have been conditionally placed by the Joint Brokers with new and existing institutional investors other than those which may be subscribed for by Woodford Investment Management, on behalf of its clients.

Could be finally turning a corner...

aldwickk - 24 Apr 2015 07:59 - 18 of 71

You haven't added a EPIC to your thread

Ruthbaby - 24 Apr 2015 10:04 - 19 of 71

Where do I do that or is it to late?

skinny - 24 Apr 2015 10:07 - 20 of 71

It's not something that we mere mortals can do, but it may be worth asking Ian to do it on this thread.

Ruthbaby - 24 Apr 2015 10:30 - 21 of 71

Thank you guys!!

Ruthbaby - 24 Apr 2015 14:48 - 22 of 71

Ah...still no epic....:-(

Ruthbaby - 29 Apr 2015 08:06 - 23 of 71


29 April 2015

Sphere Medical Holding plc

Result of Open Offer

Cambridge, UK, 29 April 2015: Sphere Medical Holding plc (AIM: SPHR.L), ("Sphere Medical" or the "Company") a leading provider of innovative monitoring and diagnostic devices for the critical care setting, announced on 13 April 2015 details of the Company's proposed fundraising through a Placing and Open Offer at 16 pence per share.

The last time and date for receipt of completed application forms and payment in full under the Open Offer was 11.00 a.m. on 28 April 2015. The Company announces that at that time that it had received valid acceptances in respect of 7,352,582 Open Offer Shares from Qualifying Shareholders with a value of some GBP1,176,413. This represents approximately 99% of the 7,425,661 Open Offer Shares offered. As a consequence, the Company has conditionally raised GBP13.2 million (before expenses) through the Placing and Open Offer.

The Placing and Open Offer are all subject to the approval of Shareholders at a General Meeting to be held at 10.00 a.m. on 30 April 2015.

Application has been made to AIM, a market of the London Stock Exchange plc, for the admission of 82,352,582 New Ordinary Shares to be issued pursuant to the Placing and Open Offer. It is expected that Admission will become effective on 1 May 2015. Following Admission, the Company will have 141,757,872 Ordinary Shares in issue.

The New Ordinary Shares, when issued and fully paid will rank equally in all respects with the Existing Ordinary Shares.

Commenting on today's announcement, Dr. Wolfgang Rencken, Chief Executive Officer of Sphere Medical, said:

"We are very appreciative of the continued support from a significant number of our long-term shareholders that have taken part in this Open Offer. The proceeds from the fundraising will further strengthen the Company's balance sheet as we accelerate the commercialisation of Proxima in Europe."

Unless otherwise defined, terms in this announcement shall have the same meanings as those defined in the shareholder circular dated 13 April 2015.

CC - 28 May 2015 19:54 - 24 of 71

I have today bought a very small holding in this stock. It's not my typical type of play as I prefer stocks with a track record and something I can latch onto.

My rationale is as follows:
1. After a number of years the product is moving to the point of real sales. The market would appear to be huge but it is difficult to quantify how fast sales will increase. I suspect it will be slower than most would like but I am patient.

2. Neil Woodford took up £4m shares at 16p and if 16p is good enough for him I'm happy to take my chances at 16.8p

3. After the placing the shares inevitably fell but I am surprised they have come all the way back to the placing price. I guess someone took up the placing but didn't really want the shares and is selling the placing shares at a profit.

4. There is a daily flow of buys which sooner or later will soak up whoever is selling. Dont' be confused by the trade pattern - all those sells reported at 16.8p are buys.

5. The directors took part in the open offer and put their own money in.

black bird - 29 May 2015 10:52 - 25 of 71

diagnostic devices , have a poor track record, buy after the next loss a/c 12pence ?

Ruthbaby - 31 May 2015 21:26 - 26 of 71

16.80p have all been buys as I have added but it was marked down as red....
No issues as I believe this will move quickly when it turns....

Ruthbaby - 01 Jun 2015 15:30 - 27 of 71

RNS...

Sphere Medical confirms that its Annual General Meeting will be held at 11.00am on Thursday, 25 June 2015 at Harston Mill, Harston, Cambridge CB22 7GG. The Notice of Annual General Meeting is set out in the Annual Report and Accounts.

Ruthbaby - 01 Jun 2015 15:31 - 28 of 71

RNS...

Sphere Medical confirms that its Annual General Meeting will be held at 11.00am on Thursday, 25 June 2015 at Harston Mill, Harston, Cambridge CB22 7GG. The Notice of Annual General Meeting is set out in the Annual Report and Accounts.

Ruthbaby - 25 Jun 2015 07:32 - 29 of 71

First Sales and Appointment of New Chairman



Cambridge, UK, 25 June 2015: Sphere Medical Holding plc (AIM: SPHR.L), ("Sphere Medical" or the "Company") a leading provider of innovative monitoring and diagnostic devices for the critical care setting, announces that, at its Annual General Meeting, which will take place at 11:00 am today at Harston Mill, Harston, Cambridge, Dr Anthony Martin, Non-Executive Chairman, will provide the following update:

The two major objectives for Sphere Medical since the beginning of the year have been: the continued commercialisation of Proxima 3 into the UK market and more latterly, into the German, Dutch and Belgium markets; and the finalisation of the development of Proxima 4 alongside Ortho-Clinical Diagnostics as well as fulfilling our obligations under the Collaboration Agreement.

I am pleased to report that the Company has delivered its first commercial order of Proxima 3 product, which represents an important milestone for the Company. Furthermore, we are continuing to grow the number of hospitals showing interest in Proxima 3 and work is continuing with these hospitals for the sale of Proxima into their intensive care settings. The evaluations Sphere has undertaken this year within hospitals have shown that Proxima can reduce the time from ordering a blood gas test to receiving the result by 40% to 60% in a typical clinical environment as well as eliminating the time the nurse is required to spend away from the patient.

Under the terms of the Collaboration Agreement with Ortho-Clinical Diagnostics, Sphere Medical has granted an option to Ortho-Clinical Diagnostics to enter into good faith negotiations for the exclusive rights to commercialise Proxima 4. In connection with this option, Sphere Medical has certain obligations to compile and deliver a data package of reports detailing key product attributes and commercial observations related to Proxima 3 and Proxima 4. Sphere Medical is on schedule to deliver all of these reports.

Work is also on schedule for the submission of the technical and design dossier files necessary for the approval of Proxima 4's CE marks. We currently expect to release these files to our Notified Body during Q3 2015.

On 30 April we announced a successful £13.2 million (gross of costs) fundraise from new and existing shareholders to further strengthen the Company's balance sheet and to enable the achievement of near-term operational and commercial value drivers which we are confident will create substantial value for our shareholders.

On 7 January we announced David Martyr's and Meinhard Schmidt's appointments to the Board as Non-Executive Directors. I indicated at that time that I would be reviewing our succession plan for the Chairmanship of Sphere Medical. I have been Chairman of Sphere Medical for ten years and over that time the Company has developed from a private company engaged in research and development to a commercially-focused public company selling its CE-marked medical device into Europe. I now believe it is time to for me to stand down from my role and therefore I am very pleased to announce that David has agreed to replace me as Chairman. I have every confidence that David's extensive experience within the medical device industry will be of significant benefit to Sphere Medical in the coming years.

Ruthbaby - 08 Jul 2015 15:49 - 30 of 71

WOW!
Big trades gone through today @ 17p......

CC - 08 Jul 2015 20:21 - 31 of 71

Trades large enough that we may well get an RNS tomorrow explaining who's been selling and therefore whether the overhang is done or there may be more to go.

black bird - 09 Jul 2015 16:12 - 32 of 71

CFO leaves legal & gen reduce more money to keep going wanted, 2m at time sold
another holder not a very good picture its a no for me BB willlook again as
previous bb 12p

Ruthbaby - 14 Jul 2015 09:08 - 33 of 71

Woodford just bought another few million shares @ 17p

http://www.moneyam.com/action/news/showArticle?id=5075334

CC - 22 Jul 2015 21:28 - 34 of 71

For those that follow Proxima 4 Data Package milestone reached today as planned on time.

SHOC have finally moved off the offer after being there for the last 3-4 weeks. WNTS the only market maker stubbornly sitting there at 19p although you can quite happily buy at 17.6p in reasonable quantity.

Ruthbaby - 23 Jul 2015 08:15 - 35 of 71

I saw that...and on time.
We should hear from OCD quite soon as to weather they wish to negotiate to take up global distributions rights for P4...
Interim results next month....good news hopefully...

CC - 08 Sep 2015 19:39 - 36 of 71

Quick update. Price has fallen with rest of general market. Interims on 22nd September where there may or may not be news on sales generation.

More interesting we had 2.8m of buys and sells yesterday which I'm betting is Woodford topping up again. No idea why he keeps topping up but assume he must be assured on it's future. He currently has 18.8% of the shares so this would take it over 20% if it's WPCT fund.

The seller is just as intrigued as there aren't many players with a chunk of shares that large to sell. I'll be glad when whoever it is finished as it appears to be holding the price back. Doesn't really matter though in a way as if Woodford keeps buying eventually the seller will run out.

Look for the RNS as confirmation in the next couple of days

Ruthbaby - 08 Sep 2015 20:13 - 37 of 71

Thanks CC.
But there are quite a few big investors in here and a few didn't take up their recent entitlements in the open offer so the seller could be from any number of holders....
Ortho recently declined to take up the world wide distribution rights which is fair enough as they are under new management and perhaps no longer interested in it.

I do recall Matthew Hall mentioning at the AGM, that there was one or two holders who expressed a willingness to exit as the company no longer met their investment criteria....
But like you, I am intrigued by the recent big trades.....
Hopefully more shall be revealed soon enough....

CC - 08 Sep 2015 21:07 - 38 of 71

You may find this useful Ruth. Since I put this together about a month ago Woodford are now at 26,664,500 before yesterday's trades. It requires a little interpretation on some of the smaller holdings as these are only ever reported at particular points in time.
I've never seen an AIM stock like this so tightly held and bit by bit becoming more so.

9i72wo.jpg

CC - 10 Sep 2015 19:26 - 39 of 71

Woodford RNS out today picking up another 3m shares. Now at 20.9%

Don't know where he got the shares from yet but the "free float" is getting smaller and smaller.

Price picked up a tiny bit today. Would be nice to think it's a permanent rise rather than the MM's taking advantage of PI's after the RNS

Ruthbaby - 11 Sep 2015 18:40 - 40 of 71

Peel Hunt have held close to 1 million shares and perhaps even more after the open offer.
He may have taken their position as they seem more freed up to make a market now...
Still no reflection in the share performance so far....
Have a good weekend...

Ruthbaby - 13 Feb 2016 08:17 - 41 of 71

New Welsh facility opened up........
Contract win in German teaching hospital.
Proxima 4 CE approval under current re view
Update at the end of this month.....full year 2015 results out.
Could be of interest...

Ruthbaby - 04 Mar 2016 16:33 - 42 of 71

Woodford still buying, I see....:-)

Ruthbaby - 11 Mar 2016 07:30 - 43 of 71

25% jump in SPHR..yesterday......
Woodford up to 26.5% now.....
Worth watching......

Ruthbaby - 11 Mar 2016 16:37 - 44 of 71

Woodford still buying...27% now..
Nice rise again today.....

CC - 11 Mar 2016 17:43 - 45 of 71

I think there's only you and me on this one Ruth. Can't say it's my best trade at least my loss is now in the recoverable area.

Rumors circulating of a bid to which I give no credibility whatsoever.

To my mind the rise is something more to do with all the sellers who didn't believe in the product have now managed to sell their shares and are no longer competing with each other day after day pushing the price down endlessly.

Whoever sold 3.2m shares at 4.5p on the day of the Finals now looks a bit foolish

Ruthbaby - 11 Mar 2016 18:06 - 46 of 71

I agree.....
I have noted that some large trades went through late this afternoon....
I believe this has finally turned a corner.....I am grateful to Woodford fund coming on board, when they did...
Have a good weekend...and hopefully a better next week.

skinny - 12 Mar 2016 10:18 - 47 of 71

CC - some are watching :-)

kimoldfield - 12 Mar 2016 14:10 - 48 of 71

😎👀 😀

Ruthbaby - 13 Mar 2016 20:59 - 49 of 71

Well my own feelings on the sudden rise is probably a speedier approval for the Proxima 4. I feel that would trigger an announcement on the WW distribution deal...which could be a good deal...if our main shareholders have any say in the matter now...
Good luck for the week a head...as well as those watching...
;-)

CC - 14 Mar 2016 13:05 - 50 of 71

It's still going vertical - I guess there must be something driving it as we have buyers at these levels who seem more than willing to soak up the short term traders stock

CC - 14 Mar 2016 13:13 - 51 of 71

Apparently an article running tomorrow in the Cambridge news. I'd be surprised if it says anything that's not already known

Ruthbaby - 15 Mar 2016 07:50 - 52 of 71

Are we due profit taking today after near 100% increase from recent lows?
Or will we continue on our merry way to 16p and last year's open offer price?

CC - 23 Mar 2016 20:01 - 53 of 71

Woodford now up to 28%, which is interesting as he bought the last lot at 9.5p and therefore this lot must have been between 10 and 15. I'd suggest mostly 12.5 as we had alot of volume at this price yesterday.

The fact he's buying at 12.5p suggests... well based on today's trades and the price the MM are willing to give me for a volume hugely over NMS, suggests he's still collecting.

Top few holdings are:
Woodford 28.0%
Wales LS 17.6%
LSP 7.7%
OCD 5.7%
Octopus 4.4%
Ruffer 4.0%
RLAM 4.0%
Directors 0.8%

So that's 72.5%

According to recent records TDW,HL,Share Centre,Barclays most representing PI's have another 6.1%

I can name a few more below 3% but perhaps they've sold in the last few weeks. Parkway Tech had 2.4% as of 25.02, Opportunities EIS had 2.3% and City Financial 2.3%.

My point? The free float is becoming incredible tight and sooner the only shareholders left will be those too stubborn to sell as they are interested to see how this plays out.

Ruthbaby - 26 Mar 2016 18:33 - 54 of 71

Well I can be included in that group....
I noticed on another BB, that the CEO of SPHR is holding a presentation this week..organized by Share Magazine... We may begin to get some press.....
I have followed Woodford's investment strategy over the years and it would seem he positions himself to be the king maker......
So in that regard I view his buying as most positive indeed. He will not bid (himself) for the company but will be in prime position to decide the future as when he feels the time is right to sell.
I would imagine he may have had talks about the next evolutionary step of the company with other parties already.......

Ruthbaby - 08 Jun 2016 20:56 - 55 of 71

Nothing new there....

Ruthbaby - 05 Sep 2016 15:28 - 56 of 71

Company awaiting CE approval for Proxima 4. Major teaching hospital in Belgium now a customer along with a distributorship for Italy....Sp looking up....

CC - 06 Sep 2016 13:44 - 57 of 71

Price turned post Brexit and then big rise as an order for P3 came through. MM's have been squeezed for stock for over a week. Now around resistance and a few sellers appearing.

MACD's look interesting

Chart.aspx?Provider=EODIntra&Code=SPHR&S

Ruthbaby - 06 Sep 2016 22:05 - 58 of 71

All indicators have turned positive and the company seems to "different" now.
Liquidity is a problem at the moment......This CE marking surely can not be far off now?

Ruthbaby - 01 Oct 2016 07:41 - 59 of 71

Proxima 4 has received CE approval.
Launching before 2016 end......
Great news!!!!

Bullshare - 14 Oct 2016 10:59 - 60 of 71

Shares Investor Evenings showcase presentations from leading companies bringing them together in one room.

 - Directors present their latest plans regarding development and growth

 - An opportunity to talk directly to the companies and personally put forward your questions

 - The chance to network with other attendees over drinks and canapés - private investors, wealth managers, fund managers and financial institutions

Who Should Attend?

The evening exposes investors to companies across various sectors. Perfect for existing investors as well as those looking for new investment opportunities.

Date:

Thursday 27th October 2016

Venue:

Novotel Tower Bridge, London EC3N, 10 Pepys Street, London, EC3N 2NR

Event Timings:
18.00 
Registration and coffee
18.30 
Presentations
• Paul Atherley, MD - Berkeley Energia (BKY)
• Michael Hunt, CFO - ReNeuron Group (RENE)
• Dr Wolfgang Rencken, CEO - Sphere Medical (SPHR)
+ More to be announced
20.30 
Drinks reception and canapés
21.30 
Close
Attendance is free, but spaces are limited. Register now to secure your place!
Berkeley Energia (BKY)
Berkeley Energia (BKY) 

Berkeley Energia Limited (BKY AIM/ASX) is a high impact, clean energy company focussed on bringing its wholly owned Salamanca project into production, commencing initial development in mid-2016.

The world class uranium project is being developed in an historic mining area in western Spain, about three hours west of Madrid. Following recent ministerial approval, the Company has now received all the European Union and National level approvals required for the initial development.

The project will generate measurable social and environmental benefits in the form jobs and skills training in a depressed rural community. It will also make a significant contribution to the security of supply of Europe’s zero carbon energy needs, where Euratom recently rated “lack of investment in new mines” as the number one risk facing European utilities.”

ReNeuron Group (RENE)
ReNeuron Group (RENE) 

ReNeuron is a leading, clinical-stage cell therapy development business.  Based in the UK, its primary objective is the development of novel cell-based therapies targeting areas of significant unmet or poorly met medical need.  

ReNeuron has used its unique stem cell technologies to develop cell-based therapies for significant disease conditions where the cells can be readily administered “off-the-shelf” to any eligible patient without the need for additional immunosuppressive drug treatments.  The Company’s therapeutic candidates for stroke disability and critical limb ischaemia are in clinical development and its cell-based treatment for blindness-causing diseases of the retina is currently in pre-clinical development. 

ReNeuron is also advancing a proprietary platform technology to exploit nanoparticles (exosomes) secreted by stem cells as potential new drug candidates targeting indications in tissue repair, fibrosis and cancer.

Sphere Medical (SPHR)
Sphere Medical (SPHR) 

Sphere Medical is a dynamic and growing company specialising in the development of innovative medical monitoring and diagnostic equipment. Their products are used in a wide range of medical applications, enabling faster clinical decision-making and improved patient outcomes, whilst providing efficiencies that result in reduced healthcare costs.

Sponsored by:
AJ Bell Youinvest
Shares

Bullshare - 01 Mar 2017 10:20 - 61 of 71

Come along to one of our well know Shares Investor Evenings where you will have the chance to listen and talk to directors of dynamic listed companies. At this event  on 23 March we have Directors from Sound Energy, Sphere Medical and Valirx.

 - Listen to Directors present their latest plans regarding development and growth of their business

 - Talk directly to the companies, get to know the Directors and personally put forward your questions

 - Network with other attendees including private investors, wealth managers, fund managers and financial institutions over drinks and canapés

Who Should Attend?

The evening exposes investors to companies and funds across various sectors. Perfect for existing investors as well as those looking for new investment opportunities.

Date:

Thursday 23rd March 2017

Venue:

Novotel Tower Bridge, London EC3N, 10 Pepys Street, London, EC3N 2NR

Event Timings:
18.00 
Registration and coffee
18.30 
Presentations
• James Parsons, CEO - Sound Energy (SOU)
• Dr Wolfgang Rencken, CEO - Sphere Medical (SPHR)
• Dr. George Morris, Chief Operations Officer - Valirx (VAL)
+ More to be announced
20.30 
Drinks reception and canapés
21.30 
Close
Sound Energy (SOU)
Sound Energy (SOU) 

Sound Energy is a well-funded African and European upstream gas company, listed on AIM, with a recent significant discovery in Morocco, a cornerstone investor, a strategic partnership with Schlumberger (one of the largest companies in our sector) and a potentially transformational drill programme.

We are pursuing an onshore gas strategy underpinned by strong European gas fundamentals, which is proving very robust to the current oil price environment and to an increasingly carbon-conscious world (where gas is, rightly, seen as a cleaner alternative to coal and oil).

Sphere Medical (SPHR)
Sphere Medical (SPHR) 

Sphere Medical is a dynamic and growing company specialising in the development of innovative medical monitoring and diagnostic equipment. Their products are used in a wide range of medical applications, enabling faster clinical decision-making and improved patient outcomes, whilst providing efficiencies that result in reduced healthcare costs.

Valirx (VAL)
Valirx (VAL) 

Valirx Plc is an oncology-focussed Biopharmaceutical Company, developing treatments and diagnostics. Technologies are selected by using rigorous clinical and commercial processes to address unmet market needs.

Clinical lead product is VAL201, a peptide for prostate cancer with follow-on indications in ovarian and breast cancers and endometriosis. Product VAL401, is a small molecule reformulation for lung cancers.

The Company’s proprietary technology platform, GeneICE, enables selective silencing of rebellious genes’ inappropriate activity. VAL101, the first GeneICE therapeutic, targets and reduces expression of Bcl-2, implicated in about half of cancers. GeneICE extension to neurology and inflammatory diseases will follow.

A novel diagnostic, the Nav3 system, detects pre-cancerous, cancerous and metastatic cells in tissue samples even before a tumour forms; indicating potential malignant formation.

Sponsored by:
AJ Bell Youinvest
PrimaryBid

Ruthbaby - 16 Mar 2017 21:17 - 62 of 71

I really am not sure if anything new will be mentioned at this presentation. However there is an improved appetite for the latest Proxima device. Blood saving alone make it an interesting device to have at least one on an ICU unit for very sick patients....

Ruthbaby - 29 Mar 2017 08:10 - 63 of 71

Someone posted the presentation on another bb
https://www.sharesmagazine.co.uk/video/dr-wolfgang-rencken-ceo-of-sphere-medical-sphr-2

Ruthbaby - 02 May 2017 22:03 - 64 of 71

First children's hospital to take up Proxima.....Manchester....
This is very good news...

CC - 03 May 2017 20:20 - 65 of 71

Good news Ruth. Pro's and con's to this story.

For the first time we now have evidence the product will sell in a commercial way. Orders from 6 hospitals in the last 4 months.

They are going to need more cash in the next 6 months, possibly sooner. Whether that comes from their existing lender SVB or shareholders or a combination of both remains to be seen.

I suggest the balance between sales growth and therefore reduction in cash burn vs funding required is finely balanced. If they can get to 10 orders by June then I think all concerns over future funding will disappear.

Ruthbaby - 04 May 2017 19:39 - 66 of 71

But the much sought after traction in sales......looks finally to be beginning.
I will most certainly be adding to my holding if another open offer comes round...which is not 100% certain yet.
I believe that most forecasts on potential sales has never included pediatric customers.
Very strange as they are the ones at most risk from hospital anemia... Manchester is a big contract win. There network in the North Western area is very respected. I expect other orders to flow from this validation alone. Italy now open and doing business and Spain about to launch this week. The technology is fantastic. Remember all these units going out to customers will build up the data base for applying for USA license in a year or so....I think this is where SVB are looking....hence the £3 million loan...
Great contact profile....

Ruthbaby - 06 Jun 2017 11:31 - 67 of 71

Beginning to gain sales...recent update....

Sphere Medical Holding plc

Commercialisation Update
~ Proxima building European sales traction in adult and paediatrics ~



Sphere Medical Holding plc (AIM: SPHR.L), an innovative point-of-care monitoring and diagnostic devices company, today provides a commercialisation update for its wholly-owned Proxima platform product.



Proxima 4 was launched into the European market in December 2016 and a positive reaction to the product has been received with forward visibility of an expanding sales pipeline. Over 40 hospital departments have engaged with Sphere Medical on Proxima 4 and have requested evaluations, of which more than 30 have undergone a product demonstration. Evaluations, in which the system is connected to patients, have been conducted at 14 hospital departments and to date six hospital departments across three countries have placed orders for Proxima 4, more than doubling the key metrics over the two months from the announcement of our Full Year Results on 28 February 2017. Follow-up discussions are underway with the other hospitals which have conducted evaluations.



One of the advantages of Proxima 4 over the previously available product, Proxima 3, is the paediatric application, where a patient's blood conservation during procedures is typically even more critical than in adults. Since the launch of Proxima 4, the system has been connected to children for the first time and the Royal Manchester Children's Hospital has already placed an order, becoming the first paediatric unit to purchase Proxima product.



In continental Europe, the list of product distributors continues to expand and now includes Eumedics Medizintechnik GmbH in Austria. Training, marketing and monitoring of patients in hospitals are now underway via Burke and Burke in Italy and Prhoinsa is on track to commence marketing in Spain imminently.



Production processes have now been fully converted to Proxima 4 from the earlier product iteration, Proxima 3, and the establishment of Sphere's manufacturing facility in Wales has continued to progress according to plan. As is normal in the ramp up of wafer based technologies, a key focus remains on increasing product yield. We have been experiencing occasional limitations on the supply of Proxima 4 sensors. However, whilst supply is currently low, the Board is confident that yields will improve and there will be sufficient supply in place to meet the sales targets for the current full year and beyond.



Commenting on the commercial traction of Proxima, Wolfgang Rencken, CEO of Sphere Medical, said: "We are very pleased with the market reaction to Proxima 4 and encouraged by the early response from customers. We look forward to building on this through 2017."

Bullshare - 29 Jun 2017 11:38 - 68 of 71

Come and celebrate 6 years of investor evenings with Shares on July 11 and receive a Shares goody bag worth over £150!.

We can’t believe that 6 years have passed since we started our investor evenings, in that time many 1000’s of private investors, fund managers, brokers and analysts have come along and heard from 100’s of listed companies present their investment opportunity.

To celebrate our next investor evening on 11 July in London, we will give all attendees a free goody bag containing:

1)            a one year  subscription to Shares magazine digital. Each week you will receive the latest Shares digital weekly magazine where our team of experts will give you a multitude of investment ideas. You will also gain access to the Shares investor toolkit with live news, LIVE share prices, portfolio and research tools (value £120)

2)            a bottle of champagne (value £20)

3)            The DIY Investor book written by Andy Bell, CEO of AJ Bell (RRP £17.99)

 

On the evening hear from:

MetalNRG (NEX.MNRG) MetalNRG is an NEX Exchange quoted natural resource investing company seeking investments in precious and strategic metals. Metal NRG is reviewing opportunities in various commodities and jurisdictions and anticipates updating the market shortly with regard to its initial target investments. It recently announced its first investing step with the creation of the Palomino Cobalt Project in Western Australia. MetalNRG’s CEO, the well-known resources entrepreneur Paul Johnson (ex-CEO of Metal Tiger), will provide an update on the company’s investment strategy.

Midatech Pharma (MTPH) -  Midatech has a balanced portfolio of fast-growth marketed oncology products and development programmes for its own products, using its proprietary platform technologies to target diseases with unmet medical need.  Midatech offers the potential for rapid revenue growth through its differentiated product portfolio and exciting development pipeline, supported by strong IP and, an ambitious and highly experienced leadership team.

Sphere Medical (SPHR) - Sphere Medical’s vision is to become a leading solution provider to the critical care market offering innovative, frequent on demand, point of care diagnostic and monitoring products to enable closer control of therapeutic response, improve patient outcomes and reduce the overall cost of care. The Company’s strategy is focused on the Proxima platform for measuring blood gases, electrolytes and metabolites. The latest generation of the product, Proxima 4, was launched in December 2016 and is being marketed directly to the critical care market in the UK, Germany, The Netherlands and Belgium, and by distributors in Italy and Spain. 

Xpediator -  Xpediator Plc is expected to IPO on the London Stock Exchange’s AIM market in July 2017. It is a well-established international provider of freight management services operating across the UK and Europe with a particular focus on, and expertise in, the CEE markets. The Group currently employs over 600 people with its operational headquarters in Braintree, England, and country offices in Bulgaria, Lithuania, Estonia, Macedonia, Montenegro, Moldova, Romania and Serbia operating from 22 sites in total.

 

Places at this event are very limited, so register now for your free ticket.

 

Who Should Attend?

The evening is a perfect opportunity for existing shareholders or potential investors to hear from those that matter, the directors running the companies and fund managers managing their fund. Who better to explain the future potential and strategy. 

Date:

Tuesday 11 July 2017

Venue:

Novotel Tower Bridge, London EC3N 2NR, 10 Pepys Street, London, EC3N 2NR

Event Timings:
18.00 
Registration and coffee
18.30 
Presentations
• Paul Johnson, CEO - Metal NRG (MNRG)
• Dr Jim Phillips, CEO - Midatech Pharma (MTPH)
• Dr Wolfgang Rencken, CEO - Sphere Medical (SPHR)
• Stephen Blyth, CEO - Xpediator
+ More to be announced
20.30 
Drinks reception and canapés
21.30 
Close
Metal NRG (MNRG)
Metal NRG (MNRG) Metal NRG is an NEX Exchange quoted natural resource investing company seeking investments in precious and strategic metals.  Metal NRG is reviewing opportunities in various commodities and jurisdictions and anticipates updating the market shortly with regard to its initial target investments.

 

 

Midatech Pharma (MTPH)
Midatech Pharma (MTPH) 

Midatech is a nanomedicine company focused on the development and commercialisation of multiple, high-value, targeted therapies for major diseases with unmet medical need. It is advancing a pipeline of novel clinical and pre-clinical product candidates based on its proprietary drug conjugate and sustained release delivery platforms with a clear focus on the key therapeutic areas of diabetes, cancer and neuroscience/ophthalmology. Midatech’s strategy is to develop its products in-house in rare cancers and with partners in other indications, and to accelerate growth of its business through strategic acquisition of complementary products and technologies.

Sphere Medical (SPHR)
Sphere Medical (SPHR) 

Sphere Medical is a dynamic and growing company specialising in the development of innovative medical monitoring and diagnostic equipment. Their products are used in a wide range of medical applications, enabling faster clinical decision-making and improved patient outcomes, whilst providing efficiencies that result in reduced healthcare costs.

Xpediator
Xpediator 

Xpediator is the holding company for the Group, a well-established international provider of freight management services operating across the UK and Europe with a particular focus on, and expertise in, the CEE markets.

 
he Group currently employs over 600 people with its operational headquarters in Braintree, England, and country offices in Bulgaria, Lithuania, Estonia, Macedonia, Montenegro, Moldova, Romania and Serbia operating from 22 sites in total.
 
The Group has three main business areas which are managed autonomously on a day-to-day basis but directed centrally to cross-sell services to the Group’s customer base:
 
- Freight forwarding, trading under the Delamode brand.
- Logistics and warehousing, trading under the Delamode brand and EMT; and pallet distribution services, trading under the Pall-Ex brand.
- Transport services, trading under the Affinity brand.

 

Sponsored by:
AJ Bell Youinvest
PrimaryBid

Ruthbaby - 30 Jun 2017 12:06 - 69 of 71

Philips link 'a huge step forward' for Sphere Medical - CEO Wolfgang Rencken
10:19 30 Jun 2017

Wolfgang Rencken, chief executive of Sphere Medical Holding PLC (LON:SPHR) tells Proactive he's hugely excited their Proxima 4 critical care blood gas monitoring system can now work with electronics giant Philips' IntelliVue Patient Monitoring Systems.
The combination with Philips’ equipment means that Proxima's results can be recorded and displayed alongside other critical monitoring information, such as blood pressure, ECG, EEG, respiratory rate, cardiac output and temperature.
http://tinyurl.com/yafff2gm

Ruthbaby - 10 Jul 2017 20:18 - 70 of 71

I read elsewhere....SPHR not now attending....

hangon - 07 Sep 2017 15:02 - 71 of 71

Recent reading (DYOR) suggests Sphere Medical has been soliciting for investment as late as 2017, perhaps they ducked-out of the July 2017 Exhibition, dunno. for any one of many reasons.
Yet records since 2012 show sp has declined from ~£1 (DYOR) to c.1p today. That is a massive loss by any imagination and Directors should be held to account over what they propose doing to restore the money entrusted to them by investors, who relied on the Company's outpourings of "Prospects" - which includes each and every Director, if I'm not mistaken ( Otherwise, what useful function are they performing?)....DYOR.
RNS:- What I read today( Sept 2017)- suggests Sphere Medical are cancelling their AIM-listing and going private....
well let's hope the good-ship has enough lifeboats.
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