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Hutchison China Meditech (HCM)     

dreamcatcher - 07 Aug 2012 21:04




Hutchison China MediTech Limited ("Chi-Med") is a China-based globally-focused healthcare group which researches, develops, manufactures and sells pharmaceuticals and health-related consumer products.

Its Innovation Platform focuses on discovering and developing innovative therapeutics in oncology and autoimmune diseases for the global market. Its Commercial Platform manufactures, markets and distributes prescription drugs and consumer health products in China.

Chi-Med is listed on the London Stock Exchange’s AIM market (AIM: HCM). It is majority owned by CK Hutchison Holdings Limited (SEHK: 0001), a leading international conglomerate committed to innovation and technology with over a quarter of a million employees in more than 50 countries and annual sales of over US$50 billion.

http://www.chi-med.com/eng/global/home.php


free counters
Chart.aspx?Provider=EODIntra&Code=HCM&SiChart.aspx?Provider=EODIntra&Code=HCM&Si

dreamcatcher - 19 May 2014 19:01 - 67 of 190

Hutchison China MediTech: UBS upgrades from neutral to buy with a target price of 1000p.

dreamcatcher - 22 May 2014 07:08 - 68 of 190


Phase I data to be presented at ASCO

RNS


RNS Number : 6785H

Hutchison China Meditech Limited

22 May 2014






Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)



Phase I clinical data for selective VEGFR, c-Met and VEGFR/FGFR inhibitors to be presented at the 2014 ASCO Annual Meeting



London: Thursday, 22 May 2014: Chi-Med today announces that data from recent Phase I and Phase Ib clinical studies by Hutchison MediPharma Limited ("HMP"), its majority owned R&D company, will be presented at the 50th Annual Meeting of the American Society of Clinical Oncology ("ASCO") to be held in Chicago, Illinois, USA from 30 May to 3 June 2014. These presentations will include additional data on fruquintinib (HMPL-013), AZD6094 (HMPL-504/volitinib) and sulfatinib (HMPL-012), three novel and highly selective small molecule drugs discovered by HMP. Presentations on AZD6094 were prepared jointly with HMP's collaboration partner AstraZeneca AB (publ) ("AstraZeneca").



ASCO is a non-profit organisation founded in 1964 with the goals of improving cancer care and prevention. Nearly 30,000 oncology practitioners belong to ASCO, representing all oncology disciplines and subspecialties. Members include physicians and health-care professionals in all levels of the practice of oncology. The ASCO Annual Meeting brings these people together to find cutting-edge scientific presentations and comprehensive educational content.



HMP will have one presentation on each of the three novel kinase inhibitors, as follows:




Title:

A Phase Ib study of VEGFR inhibitor fruquintinib in patients with pre-treated advanced colorectal cancer


Abstract:

#3548


Track:

Gastrointestinal (Colorectal) Cancer


Date & Time:

Saturday, 31 May 2014, 8:00 AM







Title:

First-in-human Phase I study of a selective c-Met inhibitor AZD6094 (HMPL-504/volitinib) in patients with advanced solid tumours


Abstract:

#11111


Track:

Tumour Biology


Date & Time:

Saturday, 31 May 2014, 1:15 PM







Title:

First-in-human (FIH) Phase I study of a selective VEGFR/FGFR dual inhibitor sulfatinib with milled formulation in patients with advanced solid tumours


Abstract:

#2615


Track:

Developmental Therapeutics


Date & Time:

Sunday, 1 June 2014, 8:00 AM




Presentations will be made available at http://chi-med.com/eng/irinfo/presentations.htm. Further information about the 2014 ASCO Annual Meeting and the abstracts are available in Notes to Editors and at am.asco.org.



Ends

dreamcatcher - 23 May 2014 07:21 - 69 of 190


Initiation of Phase II Study in Renal Cancer

RNS


RNS Number : 8477H

Hutchison China Meditech Limited

23 May 2014






Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)



Initiation of AZD6094 (HMPL-504/volitinib) Global Phase II Study in Papillary Renal Cell Carcinoma



London: Friday, 23 May 2014: Chi-Med today announces that Hutchison MediPharma Limited ("HMP"), Chi-Med's majority owned R&D company, and AstraZeneca AB (publ) ("AstraZeneca") have initiated a global Phase II study to evaluate the efficacy and safety of AZD6094 (HMPL-504/volitinib) ("AZD6094"), HMP's potent and highly selective c-Met inhibitor, in patients with papillary renal cell carcinoma ("PRCC"). Under the terms of the global licence granted to AstraZeneca by HMP in 2011, AstraZeneca will now make a milestone payment to HMP, and will lead and fund this development outside of China.



PRCC represents about 10 to 15% of all new cases of kidney cancer and advanced disease has no approved therapy today. Molecular alterations leading to aberrant activation of the c-Met signalling pathway have been well documented in PRCC and effective inhibition of c-Met has been considered a potential treatment pathway for PRCC.



AZD6094 has been demonstrated to inhibit the growth of tumours in a series of preclinical disease models, selectively for those tumours with aberrant c-Met signalling. Phase I dose escalation studies were initiated in Australia and China in 2012 and 2013 respectively. AZD6094 has demonstrated good safety and tolerability and favourable pharmacokinetic properties in late stage cancer patients, and has shown encouraging anti-tumour activity in several tumour-types, in particular for metastatic PRCC. The results from the Phase I studies are planned to be released at the 50th annual meeting of the American Society of Clinical Oncology which will be held from 30 May to 3 June 2014 in Chicago, Illinois, USA.



This trial is an open-label, single-arm, multicentre, Phase II, study designed to evaluate the efficacy and safety of AZD6094 in patients with locally advanced or metastatic PRCC. Approximately 20 centres in the United States, Canada, and Europe will participate in the study. The primary objective of this study is to assess the anti-tumour activity of AZD6094 in patients with PRCC as measured by overall response rate according to Response Evaluation Criteria in Solid Tumours ("RECIST") (version 1.1). The secondary objectives for this study are to: assess the progression free survival and duration of response in patients with PRCC according to RECIST (version 1.1); assess the safety and tolerability of AZD6094 in the treatment of patients with PRCC; characterise the pharmacokinetics and pharmacodynamics of AZD6094 and metabolites following administration to steady state after multiple dosing when given orally; and obtain a preliminary assessment of AZD6094 activity in blood and tumour by evaluation of biomarker changes which may include, but not limited to, phosphorylated c-Met. Exploratory objectives include an investigation of predictive markers and acquired resistance to AZD6094 that may be observed in blood and tumour from patients treated with AZD6094.



"It is pretty exciting to see trials being developed in this rare histology. PRCC is an unmet medical need in the field of kidney cancer and targeting MET is a very reasonable strategy," said Toni Choueiri, MD, of the Dana-Farber Cancer Institute and Head of the Steering Committee of the Phase II trial.



Christian Hogg, Chief Executive Officer of Chi-Med said, "We are delighted to see the initiation of this Phase II trial for AZD6094 in PRCC as this represents a major milestone for both the compound and for HMP. The data which has driven this decision to invest in a PRCC study is compelling and shows the quality of both the compound itself and the joint development team which has been built between HMP and AstraZeneca. There are enormous opportunities for AZD6094 in other cancer types and we are particularly excited by the potential to combine with other compounds."



"Through this great collaboration we are able to increase our understanding of the genetic changes which drive different cancers to grow and to develop medicines designed to address and overcome those genetic drivers. This is a core part of our oncology strategy to deliver personalised healthcare to patients," said Susan Galbraith, Vice President, Head of Oncology Innovative Medicines, AstraZeneca.

dreamcatcher - 30 May 2014 15:40 - 70 of 190


Gains rights to six prescription drug products

RNS


RNS Number : 4440I

Hutchison China Meditech Limited

30 May 2014












Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)





Chi-Med and Shanghai Traditional Chinese Medicine expand commercial cooperation





London: Friday, 30 May 2014: Chi-Med, the pharmaceutical and healthcare company based primarily in China, today announces that its long-term joint venture partner, Shanghai Traditional Chinese Medicine Co. Ltd. ("STCM"), through its affiliates, have agreed to grant Shanghai Hutchison Pharmaceuticals Limited ("SHPL", a joint venture between Chi-Med and STCM) exclusive rights to sell six prescription drug products in China.



Chi-Med, through its SHPL joint venture, will exclusively commercialise these six products in China for an initial ten-year term. The six prescription drug products, which had aggregate sales in 2013 of RMB45 million (US$7.3 million), cover multiple therapeutic areas including cerebrovascular disease, prostate health, bronchitis, cancer pain and kidney disease. The grant of these rights comes as part of a broader commercial restructuring of the SHPL joint venture, which although having no impact on equity structure or day-to-day operations, will allow for the expansion of its business scope.



Christian Hogg, Chief Executive Officer of Chi-Med said: "Chi-Med's partnership with STCM has enjoyed great success over the past thirteen years and has built a considerable commercial presence, with over 1,600 medical sales representatives operating in about 600 towns and cities covering over 13,000 hospitals throughout China. We appreciate the faith that STCM is entrusting in us to commercialise these important products. We expect this to build material value for our SHPL joint venture over the coming years."





Ends

dreamcatcher - 04 Jun 2014 14:28 - 71 of 190


Director's Shareholding

RNS


RNS Number : 8479I

Hutchison China Meditech Limited

04 June 2014












Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)





Director's Shareholding





London: Wednesday, 4 June 2014: Chi-Med received notification on 3 June 2014 that Mr Christopher Nash, Independent Non-executive Director of Chi-Med, purchased 4,036 ordinary shares of US$1.00 each in Chi-Med (the "Shares") at a price of GBP8.42 each on
3 June 2014.



Following this purchase, Mr Nash is beneficially interested in 30,542 Shares, representing approximately 0.06% of the current issued share capital of Chi-Med.

dreamcatcher - 05 Jun 2014 07:20 - 72 of 190


Initiation of fruquintinib Phase II study

RNS


RNS Number : 9070I

Hutchison China Meditech Limited

05 June 2014






Hutchison China MediTech Limited ("Chi-Med")
(AIM: HCM)

Initiation of fruquintinib Phase II study in non-small cell lung cancer



London: Thursday, 5 June 2014: Chi-Med today announces that Hutchison MediPharma Limited ("HMP"), its majority owned R&D company, has initiated a Phase II clinical trial in non-small cell lung cancer ("NSCLC") patients in China for fruquintinib (HMPL-013), its investigational small molecule agent that is designed to selectively inhibit vascular endothelial growth factor receptors ("VEGFR"). Preparations and patient screening began earlier this year, with the first patient dosed on 4 June 2014.



This randomised, double-blind, placebo-controlled, multi-centre, proof-of-concept ("POC") Phase II study is targeted at treating non-squamous NSCLC patients who have failed second-line standard chemotherapy. This trial is to evaluate the efficacy and safety of fruquintinib versus placebo in NSCLC patients. All patients will receive best supportive care. The primary endpoint is progression free survival, with secondary endpoints including disease control rate, overall response rate, overall survival and safety. Approximately 90 patients will be enrolled, with top-line results expected in 2015.



Fruquintinib is designed to selectively inhibit VEGF receptors, including VEGFR1, 2, and 3. In the first-in-human Phase I clinical trial, 40 late-stage cancer patients were treated with fruquintinib. Detailed results of the Phase I clinical trial were presented at the annual meeting of the American Association for Cancer Research in April 2013, and are available at http://chi-med.com/eng/irinfo/presentations.htm. Based on the Phase I data, the first POC Phase II study was initiated on 2 April 2014, which was a randomized, double-blind, placebo-controlled, multi-centre Phase II clinical trial targeted at treating patients with locally advanced or metastatic colorectal cancer.



In October 2013, HMP entered into a licensing, co-development and commercialisation agreement in China with Eli Lilly and Company for fruquintinib.





Ends

dreamcatcher - 18 Jun 2014 07:13 - 73 of 190


Start of Phase I clinical trial with HMPL-523

RNS


RNS Number : 8004J

Hutchison China Meditech Limited

18 June 2014






Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)



Initiation of Phase I clinical trial of novel Syk Inhibitor HMPL-523 for autoimmune diseases



London: Wednesday, 18 June 2014: Chi-Med today announces that Hutchison MediPharma Limited ("HMP"), the majority owned R&D company of Chi-Med, has initiated the first-in-human Phase I clinical trial of HMPL-523 in Australia. HMPL-523 is a novel, highly selective and potent small molecule inhibitor targeting spleen tyrosine kinase, also known as Syk, a key component in B-cell receptor signalling. HMPL-523 is HMP's second active immunology programme in clinical development. The first drug dose was administered on 17 June 2014.



As one of the major cellular components of the immune system, B-cells play pivotal roles in autoimmune diseases. Targeted B-cell receptor signalling therapy has been proven to be clinically effective for the treatment of rheumatoid arthritis ("RA") and B-cell malignancies, leading to scientific and commercial success. Syk is an essential enzyme involved in B-cell receptor signalling pathway and a novel target for investigational therapies in immunology and oncology.



HMPL-523 is being developed as an oral formulation for the treatment of autoimmune diseases such as RA and lupus. In preclinical studies, HMPL-523 demonstrated superior potency and kinase selectivity, a reversal of the progression of joint inflammation and bone erosion along with a reduced production of multiple pro-inflammatory cytokines, as well as a favourable safety margin in both rodent and non-rodent toxicology studies.



The first-in-human trial aims to establish the safety profile of HMPL-523. This randomised, double blind, placebo-controlled, dose-escalating study of the safety, tolerability and pharmacokinetics of single and repeat doses of HMPL-523 will be conducted in healthy volunteers. Initial results are expected around the end of this year.



"For these chronic inflammatory conditions, it is critically important to understand if the high Syk selectivity and very good pharmacokinetic properties of HMPL-523 in preclinical studies bear out into a good human safety profile," said Christian Hogg, CEO of Chi-Med. "Should this be proven in this Phase I trial, this drug candidate will have potential as an effective oral treatment for patients with debilitating autoimmune diseases, for whom many existing treatments are limited or only modestly efficacious at safe doses," he added.



Ends

dreamcatcher - 15 Jul 2014 17:12 - 74 of 190

Chart.aspx?Provider=EODIntra&Code=HCM&Si

dreamcatcher - 16 Jul 2014 17:44 - 75 of 190

Interim Result
29 Jul 14 Hutchison China Meditech Ltd [HCM]

dreamcatcher - 29 Jul 2014 07:28 - 76 of 190


Interim Results

RNS


RNS Number : 5395N

Hutchison China Meditech Limited

29 July 2014












Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)



Interim Results for the Six Months Ended 30 June 2014



China Healthcare Division profit up 20%. Drug R&D Division progressing 10 clinical trials.

Strong outlook.





London: Tuesday, 29 July 2014: Chi-Med, the China-based healthcare and consumer products group, today announces its unaudited financial results for the six months ended 30 June 2014.

Chi-Med Group results are reported under International Financial Reporting Standard, IFRS 11 "Joint Arrangements" ("IFRS11"), which requires the equity accounting principle for the reporting of joint ventures ("JVs") which means that the income statements and statements of financial position of JVs are not proportionately consolidated as they have been in the past. However, total revenues of the JVs will continue to be disclosed on a voluntary basis under the divisional summaries below.

Results are reported in US dollar currency unless otherwise stated.



Group Results

· Revenue, under IFRS11, on continuing operations up 73% to $30.3 million (H1 2013: $17.6m).

· Net profit attributable to Chi-Med equity holdersup 97% to$6.4 million (H1 2013: $3.3m).

· Stable cash position: cash and cash equivalents at the Chi-Med Group level of $59.4 million (31 December2013: $46.9m); in addition, and not included at Chi-Med Group level, cash and cash equivalents held at the JV level of $91.6 million (31 December 2013: $99.0m).



China Healthcare Division

· Total sales of subsidiaries and JVs up 15% to $261.7 million (H1 2013: $227.5m).

· Net profit attributable to Chi-Med equity holders up 20% to $17.3 million (H1 2013: $14.4m).

· Commercial restructure complete - Good Supply Practice ("GSP") distribution companies now in place to enable the 2,700-person commercial team to sell third party/related party products.

· China low-price drug policy and key raw material price declines providing profitability tailwind.



Drug R&D Division

· Revenue of $9.9 million (H1 2013: $10.5m) from an AZD6094 (HMPL-504/volitinib) development milestone and service income from Nutrition Science Partners Limited ("NSP") and Janssen Pharmaceuticals Inc. (part of the Johnson & Johnson group of companies) ("Janssen").

· Net loss attributable to Chi-Med equity holders up 31% to $6.3 million (H1 2013: -$4.8m) due to continuing NSP investment in HMPL-004 global Phase III registration trials.

· 10 clinical trials progressing rapidly and building value. 2 Phase III registration studies on HMPL-004 in ulcerative colitis (NATRUL-3 and NATRUL-4); 3 Phase II proof-of-concept studies (AZD6094 in papillary renal cell carcinoma and fruquintinib in third-line colorectal and non-small cell lung cancer); 3 Phase Ib expansion studies (AZD6094 non-small cell lung cancer, sulfatinib in neuroendocrine tumours, and epitinib in non-small cell lung cancer with brain metastasis); and 2 Phase I studies (HMPL-523/Syk inhibitor for inflammation and theliatinib in solid tumours).

· Spending of $19.8 million (H1 2013: $15.2m) on clinical trials balanced by aggregate $20.1 million (H1 2013: $38.1m) cash and equity injections and contractual obligations from partners received by Drug R&D Division subsidiaries and JVs.



Consumer Products Division

· Sales from continuing operations up 16% to $6.4 million (H1 2013: $5.5m) from expansion of the broad organic and natural product line of Hutchison Hain Organic Holdings Limited ("Hutchison Hain Organic").

· Breakeven net profit on continuing operations attributable to Chi-Med equity holders of $0.0 million (H1 2013: -$0.4m).



Christian Hogg, CEO of Chi-Med, said:

"Chi-Med has significantly increased its net profit at a time when it is managing 10 clinical trial programmes and maintaining a deep and active discovery research programme, which together is adding substantial shareholder value. This is an achievement which is testimony to the balance of our businesses, our common sense approach to financing and our strategy of collaboration with powerful industry partners to help accelerate and enhance our own programmes.

We expect to continue adding significant shareholder value in the second half and beyond."

dreamcatcher - 29 Jul 2014 16:20 - 77 of 190

Hutchison China Meditech: Panmure Gordon raises target price from 950p to 1200p keeping a buy recommendation.

dreamcatcher - 30 Jul 2014 18:56 - 78 of 190

Hutchison China MediTech: UBS raises target price from 1000p to 1250p keeping a buy recommendation.

dreamcatcher - 09 Aug 2014 22:45 - 79 of 190

MIDAS SHARE TIPS: Chinese drugs firm MediTech looks healthy after doubling in three years

By Joanne Hart, Financial Mail On Sunday

Published: 22:18, 9 August 2014 | Updated: 22:18, 9 August 2014

The Chinese spend an average £160 per head a year on healthcare compared with more than £5,000 in the US.

The figure is so low because for decades Chinese communism did not involve state healthcare. If people fell ill, they paid for treatment or went without.


However, government spending on healthcare rose tenfold from 2005 to 2013, hitting £80billion last year and further expansion is scheduled for years to come.


Good prognosis: Chinese spending on healthcare is rising



Fast-growing drugs firm Hutchison China MediTech is well-positioned to reap the benefits. Midas recommended the shares in May 2011, when they were 447½p.


After struggling during that year, they have progressed in leaps and bounds and are now trading at 1032½p.

City brokers believe they have further to run, but investors who have more than doubled their money in the past three years may be wondering if they should hedge their bets and sell some stock now.


Founded in 2000, Hutchison China MediTech was set up as a subsidiary of the giant Hong Kong conglomerate Hutchison Whampoa. Focused on developing, manufacturing and selling drugs and wellbeing products in China, the business, known as Chi-Med, listed on Aim in 2006.


The group has grown fast since then, running three main divisions: a consumer products arm selling wellbeing items such as organic tea and healthy snacks; a healthcare arm selling prescription and overthe- counter drugs; and a research and development arm working on new drugs.

It is this last division which is expected to deliver the most exciting growth over the next few years. The firm has set up joint ventures with international players such as AstraZeneca, Johnson & Johnson and Lilly, and is in advanced trials on a number of cancer treatments.

Chi-Med is also working with Nestle on a drug based on traditional Chinese herbal remedies for Crohn’s disease and related conditions.


News on the latest trial of this product is expected later this month and could trigger further investment by Nestle if results are good or a winding down of the trial if results are poor.

The healthcare business used to focus on traditional Chinese medicine – still the first option for many Chinese. Increasingly, however, consumers take conventional drugs alongside herbal remedies, so Chi-Med has broadened its offer.


The group sells more than 200 drugs, mainly for colds, flu and heart disease, and runs a sales force of more than 2,500 across 600 Chinese cities.


Until recently, Chi-Med sold only its own products, including two household brands, but it now sells other manufacturers’ drugs too, which should boost profits.

The consumer business has been slow to take off, as many Chinese are as yet uninterested in designer teas and upmarket organic crisps. Looking further ahead however, this subsidiary has serious potential. In the first six months of this year, group profits after tax doubled to $6.4million (£3.8million) compared with the same period last year.


Analysts forecast a 45 per cent increase in full-year figures to $17.5million, rising to $25million next year.


Midas verdict: Chi-Med has made good progress and should continue to deliver. Investors who bought in 2011 should hedge their bets and sell 50 to 60 per cent of their stock. New investors should buy on any short-term weakness.


Traded on: Aim


Ticker: HCM


dreamcatcher - 13 Aug 2014 18:57 - 80 of 190


HMPL-004 Interim Analysis

RNS


RNS Number : 9920O

Hutchison China Meditech Limited

13 August 2014






Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)



HMPL-004 NATRUL-3 interim analysis result



London: Wednesday, 13 August 2014: Nutrition Science Partners Limited ("NSP"), a 50/50 joint venture between Chi-Med and Nestlé Health Science SA, today announces that a planned interim analysis was conducted on NATRUL-3, the global Phase III induction trial of HMPL-004 vs. placebo in ulcerative colitis. An independent Data Safety and Monitoring Committee ("DSMC") evaluated the unblinded data of two doses of HMPL-004 vs. placebo, and has recommended that NSP terminate the study. No meaningful safety signals or risks for patients were identified, and further analysis and review of the data will be conducted. The NSP Board will continue to evaluate the potential opportunities of HMPL-004 in new indication areas and alternative regulatory pathways.

dreamcatcher - 21 Aug 2014 20:03 - 81 of 190


Patient enrolment in Phase II study completed

RNS


RNS Number : 6607P

Hutchison China Meditech Limited

21 August 2014












Hutchison China MediTech Limited ("Chi-Med")
(AIM: HCM)



Patient enrolment completed ahead of schedule for fruquintinib's Phase II study in colorectal cancer



London: Thursday, 21 August 2014: Chi-Med, today announces that Hutchison MediPharma Limited ("HMP"), its majority owned drug R&D company, has completed patient enrolment in a Phase II clinical trial of fruquintinib (HMPL-013) in colorectal cancer ("CRC") in China. The proof-of-concept study is investigating the efficacy and safety of fruquintinib, HMP's investigational small molecule inhibitor of vascular endothelial growth factor receptors ("VEGFR").



This randomised, double-blind, placebo-controlled, multi-centre, proof-of-concept Phase II study is targeted at treating patients with metastatic CRC, who have failed at least two prior chemotherapies, including fluoropyrimidine, oxaliplatin and irinotecan. A total of 71 patients have now been randomised to receive fruquintinib plus best supportive care ("BSC") or placebo plus BSC at a 2:1 ratio. The primary endpoint is progression free survival, with secondary endpoints including disease control rate, overall response rate, overall survival and safety. As a result of the rapid patient enrolment, data from this trial is expected in early 2015.



Fruquintinib is designed to selectively inhibit VEGF receptors, namely VEGFR1, VEGFR2, and VEGFR3. In the first-in-human Phase I clinical trial 40 patients were treated with fruquintinib. Detailed results of the Phase I clinical trial are available at http://chi-med.com/eng/irinfo/presentations.htm, and were presented at the annual meeting of the American Association for Cancer Research in April 2013. Based on the Phase I data in CRC, a Phase Ib study was initiated which treated a further 62 CRC patients. Detailed results of the Phase Ib clinical trial were presented at the annual meeting of the American Society of Clinical Oncology in May 2014, and also can be found at http://chi-med.com/eng/irinfo/presentations.htm.



In October 2013, HMP entered into a licensing, co-development and commercialisation agreement in China with Eli Lilly and Company for fruquintinib.





Ends



dreamcatcher - 01 Oct 2014 15:37 - 82 of 190


Co-promotion agreement with Merck Serono

RNS


RNS Number : 0157T

Hutchison China Meditech Limited

01 October 2014








Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)



Press Release

Chi-Med and Merck Serono sign co-promotion agreement



London: Wednesday, 1 October 2014: Chi-Med, the pharmaceutical and healthcare company based primarily in China, today announces that Chi-Med, through its subsidiary Hutchison Whampoa Sinopharm Pharmaceuticals (Shanghai) Company Limited ("Hutchison Sinopharm"), has signed a co-promotion agreement with Merck Serono Co., Ltd. ("Merck Serono") a subsidiary of Merck in China to market certain cardiovascular prescription drug products in China.



Hutchison Sinopharm will exclusively co-promote Merck Serono's Bisoprolol Fumarate tablets, under the Concor® trademark, in several provinces in China. Concor® is a major brand in the beta-blocker sub-segment of the cardiovascular prescription drug market in China.



Chi-Med today operates a commercial network in China of approximately 1,600 cardiovascular market focused medical sales representatives, covering more than 13,000 hospitals, through its joint ventures, Shanghai Hutchison Pharmaceuticals Limited and Hutchison Sinopharm.

Ends

Enquiries

dreamcatcher - 12 Nov 2014 21:24 - 83 of 190

Signal Update

Our system’s recommendation today is to BUY. The BULLISH STOP LOSS pattern finally received a confirmation because the prices crossed above the Stop Loss level which was at 1,229.4000, and our valid average buying price stands now at 1,246.5000. The previous SELL signal was issued on 10/11/2014, 2 days ago, when the stock price was 1,198.7500. Since then HCM.L has risen by +3.98%.

Market Outlook

A rally after a bear setup can occasionally turn into an explosive long trade. We may be on the verge of catching one of them. There is now a strong positive sentiment in the market despite the absence of a bullish pattern. The bullish stop loss is finally confirmed and a BUY signal is generated. Market wants to reward the bulls. It may be now the right time to be part of this boost and bullish market sentiment by joining the growing bullish crowd.



http://www.britishbulls.com/SignalPage.aspx?lang=en&Ticker=HCM.L

dreamcatcher - 18 Nov 2014 21:47 - 84 of 190

Signal Update

Our system’s recommendation today is to STAY LONG. The previous BUY signal was issued on 12/11/2014, 6 days ago, when the stock price was 1,246.5000. Since then HCM.L has risen by +6.70%.

Market Outlook

The bulls are in full control. The negative sentiment that led to the last bearish pattern has evaporated. Besides, the signal is suggesting to STAY LONG. It is best to follow the signal and continue to hold this security


http://www.britishbulls.com/SignalPage.aspx?lang=en&Ticker=HCM.L

dreamcatcher - 19 Nov 2014 15:33 - 85 of 190

Hutchison China Meditech: Panmure Gordon raises target price from 1200p to 1500p and keeps a 'buy' recommendation.

dreamcatcher - 20 Nov 2014 16:13 - 86 of 190


Director's Shareholding

RNS


RNS Number : 5784X

Hutchison China Meditech Limited

20 November 2014












Hutchison China MediTech Limited ("Chi-Med")

(AIM: HCM)





Director's Shareholding





London: Thursday, 20 November 2014: Chi-Med received notification on 20 November 2014 that Mr Simon To, Executive Chairman and Director of Chi-Med, purchased 41,000 ordinary shares of US$1.00 each in Chi-Med (the "Shares") at a price of GBP13.50 per share on 18 November 2014.



Following this purchase, Mr To is beneficially interested in 41,000 Shares, representing approximately 0.08% of the current issued share capital of Chi-Med.

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