apple
- 25 Mar 2004 20:47
PARKIN
- 04 Sep 2006 17:11
- 907 of 1451
from what I remeber it was also on the news on Channel 4 on Friday evening.
Oakapples142
- 04 Sep 2006 19:19
- 908 of 1451
I think you will find that there has/is/will be a presentation in USA although no RNS as yet
robstuff
- 04 Sep 2006 21:56
- 909 of 1451
they used OXBs technology to deliver the protein to the cells, this is the reason for the news to affect OXB
hangon
- 06 Sep 2006 15:46
- 910 of 1451
I don't think there was any use of "Oxford's technology" - where did you gleen this, robstuff?
Certainly it was "Gene therapy" but OXB doesn't own the whole lot, there are plenty of competing alternatives within the range of gene therapy... almost as many as there are genes.
The point of OXB's therapy is that the cell is one that mankind has lived with, without any recorded side-effects. Nevertheless OXB has to go through the full phase-trials, like anyone else.
The American trials whilst newsworthy (I presume) were over a year ago and it is curious that the story should come out just a few days before OXB is about to report (early Sept06, so I understand) - and is in the process of negotiating a partner that is likely to be US-based.
This (news item) couldn't have come at a better time, despite it's wholly disconnected from OXB, other than it used Gene therapy.
( I understand the story was reported on SKY, Ch5 and maybe Ch4., but it all went quiet within a short time....)
+Good luck to OXB but I would prefer my investment to be judged on PhIII trial facts rather than media excitement.
Please DYOR, this area is very complicated and the rewards are (we understand) considerable.
Oakapples142
- 01 Dec 2006 10:40
- 911 of 1451
Anyone know what has stirred this one up this morning
Red Underwing
- 01 Dec 2006 12:43
- 912 of 1451
Do you mean apart from the buy of 8,301,417? (9:54)
That's a fairly big spoon.
Others will follow in case they miss out!
Red
Oakapples142
- 01 Dec 2006 13:14
- 913 of 1451
Hi Red - sorry yes it was the large buy (and a very odd amount) that caught me interest.
GrasperJasper
- 11 Dec 2006 10:40
- 914 of 1451
Ou est tout le monde?
Oakapples142
- 11 Dec 2006 10:43
- 915 of 1451
Ya what mate
GrasperJasper
- 12 Dec 2006 10:18
- 916 of 1451
Vous etes fantome?
potatohead
- 12 Dec 2006 12:03
- 917 of 1451
get in ERX now news out before RNS... no brainer
OzzMosiz - 12 Dec'06 - 11:44 - 14943 of 14945
Presenting it like this would've helped - nice find though.- I believe this is worthy of RNS
http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-11-2006/0004488564&EDATE=
ABOUT LY2181308 AND SURVIVIN
LY2181308 targets survivin, a molecule that supports the survival of
cells that would normally die through programmed cell death or apoptosis.
Survivin helps in the abnormal growth of cancer cells, and is abundant in
many types of cancers, including colon, brain, lung, skin and others, but
nearly nonexistent in normal cells and tissues.
-------------------------------------------------------------------------------------------------------------
http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/12-11-2006/0004488564&EDATE=
7 SURVIVIN in my patents list
Inventor: HAYES IAN (IE); COTTER TOM (IE); (+5) Applicant: EIRX THERAPEUTICS LTD (IE); HAYES IAN (IE); (+6)
EC: C07K14/47A1A; C07K14/47A33 IPC: C07K14/47; A61K38/00; C07K14/435 (+2)
Publication info: WO03091384 - 2003-11-06
-------------------------------------------------------------------------------------------------------------
CARLSBAD, Calif., Dec. 11 /PRNewswire-FirstCall/ -- Isis
Pharmaceuticals, Inc. (Nasdaq: ISIS) announced today that Eli Lilly and
Company (NYSE: LLY) highlighted two antisense oligonucleotide (ASO) drugs
in its "Update to Wall Street on Strategic Priorities and Pipeline
Progress" on Thursday. Advances with both survivin ASO (LY2181308) and
eIF-4E ASO (LY2275796) drugs were singled out among Select Early- to
Mid-Stage Pipeline Developments. Based on promising activity in early
studies, Lilly said that it is initiating Phase 2 trials for survivin ASO
in a broad range of cancers including liver cancer, prostate cancer, acute
myelogenous leukemia, ovarian cancer and non-small cell lung cancer; the
first of these trials is planned to begin this month. Lilly also said that
the Phase 1 development program for eIF-4E ASO is progressing well.
"We are pleased that Lilly includes our collaboration drugs among its
selected strategic priorities," commented C. Frank Bennett, Ph.D., Isis'
Senior Vice President of Research. "These drugs resulted from our
productive collaboration and Lilly's broad investment in antisense
technologies. We continue to work together and hope that additional drugs
will arise from our collective efforts. Lilly's progress with these
anti-cancer drugs emphasizes the broad therapeutic potential of Isis'
platform antisense technologies, and underscores our strategy of working
with partners to expand the scope of our development pipeline.
GrasperJasper
- 12 Dec 2006 13:02
- 918 of 1451
Ma foi! Un idiot-pomme de terre arrive.
robstuff
- 21 Dec 2006 11:19
- 919 of 1451
OXB is now doing deals with the big boys, see news today about a deal with Glaxo!! This is great news and endorses Oxb technology as leading edge. This should just be the beginning although if they've got something big, Glaxo will probably swallow them up before that, anyone know what percentage Kingsman or the other major shareholders own?
queen1
- 21 Dec 2006 12:43
- 920 of 1451
I totally agree robstuff. But where's the sp movement (or have the last couple of week's worth of rises been due to the imminent announcement of this news?)?
robstuff
- 22 Dec 2006 12:51
- 921 of 1451
I've seen this before with OXB, the rise normally comes a few days later so lets see. Anyway, great news and 2007 should be a blinder for OXB
queen1
- 22 Dec 2006 18:03
- 922 of 1451
Let's hope so
robstuff
- 28 Dec 2006 23:15
- 923 of 1451
In the Biotech sector, 2007 will be a year of larger Pharmaceuticals such as AstraZeneca and Glaxo SK taking over smaller companies with developments in Phase III in the areas of oncology and neurotherapy - OXB being a prime candidate
queen1
- 29 Dec 2006 09:45
- 924 of 1451
At what take-out price? OXB has an awful lot going on at present which will be of interest to the majors.
robstuff
- 29 Dec 2006 11:42
- 925 of 1451
It would have to be over double it's current price today, but next yr news and interest in the sector should take it towards a pound anyway I would think.
rayrac
- 30 Dec 2006 15:15
- 926 of 1451
Patrick Evershed
Manager of New Star Select Opportunities Fund
FTSE 100 5,250 (5,500). I fear the very large Government budget deficits, record levels of personal indebtedness and dangerously large trade deficits in the USA and UK will undermine the prolonged period of economic growth and high profit margins.
If the rate of economic growth does slow and profit margins come under pressure at least some of the exceptionally highly geared private equity funds could find themselves in trouble.
Top share Oxford BioMedica could complete value enhancing deals during the year. The first could be for its lead cancer drug TroVax. The second could be for its Parkinson's treatment, which is reputed to have gone exceptionally well in pre-clinical trials, and the last is for its LentiVector drug delivery system which is in demand from other pharmaceutical companies.