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PureTech Health’s Vedanta Biosciences boasts ‘promising’ results

ALN

PureTech Health PLC on Monday said that its founded entity, Vedanta Biosciences, has seen positive results for its lead programme, VE303.

The Boston-based clinical-stage biotherapeutics company said the phase two study data confirmed that VE303 prevented recurrent Clostridioides difficile infection, compared with placebo.

Clostridioides difficile is a type of bacteria that can cause diarrhoea. VE303 is a defined bacterial consortium therapeutic candidate designed for the prevention of recurrent Clostridioides difficile infection, PureTech said.

Vedanta Biosciences is a clinical-stage company that is developing a potential new category of oral therapies based on defined bacterial consortia. It is based in Cambridge, Massachusetts.

Darrell Pardi, chair of the Division of Gastroenterology & Hepatology at the Mayo Clinic in Rochester, Minnesota, said: ‘The notorious difficulty of preventing recurrent CDI creates a large population of patients struggling with the condition, with few therapeutic options. VE303 provides an approach that is designed to address the underlying biology in a novel way. The clinical data to-date have been extremely promising, and we are eager to see future updates on this program as it progresses through the clinic.’

Shares in the FTSE 250-listed firm were up 1.8% at 221.50 pence on Monday morning in London.

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