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The following stocks are the leading risers and fallers on AIM on Monday. ---------- AIM - WINNERS ---------- N4 Pharma PLC, up 58% at 0.79 pence, 12-month range 0.35p-1.00p. The Derbyshire, England-based pharmaceutical company focused on the development of nanoparticle technology says its Nuvec gene delivery system has successfully demonstrated targeted delivery of RNA to lung cancer cells in collaboration with US research institute SRI. The company says Nuvec particles, combined with SRI’s targeting molecules, delivered therapeutic RNA payloads specifically to non-small cell lung cancer cells. Precision targeting was achieved by functionalising Nuvec with a molecule binding to a protein which is highly expressed in epithelial cancers such as lung, breast, prostate and pancreatic cancers.T he targeted Nuvec particles confirmed selective uptake, with RNA payloads delivered only by functionalised particles. N4 Pharma said this validates Nuvec as a differentiated delivery system for RNA therapies, with applications across cancers of high unmet need. N4 added that it has also shown Nuvec can target immune cells through mannose modification in its N4 101 programme, designed as an orally delivered therapy for inflammatory bowel disease. ---------- AIM - LOSERS ---------- WH Ireland Group PLC, down 73% at 0.63p, 12-month range 0.30p-3.49p. The London-based wealth-management firm agrees a conditional disposal of its wealth management business to Oberon Investments for £1 million, with the assumption of specific contractual liabilities by Oberon. WH Ireland says its wealth management business continues to make losses, despite the implementation of further cost-saving measures, with it requiring ‘substantial investment’ to reach sustainable profitability. It adds that a capital raise to fund investment would be ‘highly dilutive’, with the transaction representing ‘the best available outcome for stakeholders’. ‘The group continues to be loss-making on an underlying basis,’ says WH Ireland, as it noted expectations for a further decline in annual revenue to around £8 million for the financial year to March 31, 2026. It ties this to the company’s inabilty to advance the top line by ‘attracting new teams and clients and retain its existing major revenue generating staff’. Following the completion of the sale, WH Ireland will become a cash shell, and the board intends to begin a wind-down of the company. As a result, WH Ireland proposes a delisting from London’s AIM. WH Ireland anticipates distributing a dividend of around 0.5p per share within 12 months of the sale completing, but notes it will be ‘impossible’ to guarantee a timescale for the distribution as a result of the wind-down. The company expects to hold a general meeting on the proposed transaction and AIM cancellation on October 9. ---------- OPG Power Ventures PLC, down 19% at 5.80p, 12-month range 4.00p-11.17p. The Isle of Man-based developer and operator of power plants in India says the goods and services tax on coal in India has been increased to 18% from 5%. At the same time, the ₹400 per tonne compensation cess previously levied on coal is expected to be abolished and subsumed within the new goods and services tax rate. Following the abolishment of the cess, companies will remain unable to claim input credits due to electricity being outside GST under the new regulations. OPG’s Indian power plants rely on coal as a primary fuel source and, based on the current coal procurement mix, the company expects an annual cost increase of around £2.5 million as a result of the tax changes. OPG says the overall impact on the tax burden for coal is dependent on its specific import and domestic and domestic procurement mix. ---------- Copyright 2025 Alliance News Ltd. All Rights Reserved.
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